136 related articles for article (PubMed ID: 20135291)
1. Neoepitope antibodies against MMP-cleaved and aggrecanase-cleaved aggrecan.
Fosang AJ; Last K; Stanton H; Golub SB; Little CB; Brown L; Jackson DC
Methods Mol Biol; 2010; 622():312-47. PubMed ID: 20135291
[TBL] [Abstract][Full Text] [Related]
2. Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent.
Fosang AJ; Last K; Maciewicz RA
J Clin Invest; 1996 Nov; 98(10):2292-9. PubMed ID: 8941646
[TBL] [Abstract][Full Text] [Related]
3. Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.
Little CB; Flannery CR; Hughes CE; Mort JS; Roughley PJ; Dent C; Caterson B
Biochem J; 1999 Nov; 344 Pt 1(Pt 1):61-8. PubMed ID: 10548534
[TBL] [Abstract][Full Text] [Related]
4. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints.
Lark MW; Bayne EK; Flanagan J; Harper CF; Hoerrner LA; Hutchinson NI; Singer II; Donatelli SA; Weidner JR; Williams HR; Mumford RA; Lohmander LS
J Clin Invest; 1997 Jul; 100(1):93-106. PubMed ID: 9202061
[TBL] [Abstract][Full Text] [Related]
5. Matrix metalloproteinases and aggrecanases cleave aggrecan in different zones of normal cartilage but colocalize in the development of osteoarthritic lesions in STR/ort mice.
Chambers MG; Cox L; Chong L; Suri N; Cover P; Bayliss MT; Mason RM
Arthritis Rheum; 2001 Jun; 44(6):1455-65. PubMed ID: 11407708
[TBL] [Abstract][Full Text] [Related]
6. Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro.
Hughes CE; Caterson B; Fosang AJ; Roughley PJ; Mort JS
Biochem J; 1995 Feb; 305 ( Pt 3)(Pt 3):799-804. PubMed ID: 7531436
[TBL] [Abstract][Full Text] [Related]
7. Calpain is involved in C-terminal truncation of human aggrecan.
Struglics A; Hansson M
Biochem J; 2010 Sep; 430(3):531-8. PubMed ID: 20618160
[TBL] [Abstract][Full Text] [Related]
8. Enzymes active in the areas undergoing cartilage resorption during the development of the secondary ossification center in the tibiae of rats ages 0-21 days: I. Two groups of proteinases cleave the core protein of aggrecan.
Lee ER; Lamplugh L; Davoli MA; Beauchemin A; Chan K; Mort JS; Leblond CP
Dev Dyn; 2001 Sep; 222(1):52-70. PubMed ID: 11507769
[TBL] [Abstract][Full Text] [Related]
9. A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs.
Swearingen CA; Chambers MG; Lin C; Marimuthu J; Rito CJ; Carter QL; Dotzlaf J; Liu C; Chandrasekhar S; Duffin KL; Mitchell PG; Durham TB; Wiley MR; Thirunavukkarasu K
Osteoarthritis Cartilage; 2010 Sep; 18(9):1159-66. PubMed ID: 20633676
[TBL] [Abstract][Full Text] [Related]
10. Mutations in the interglobular domain of aggrecan alter matrix metalloproteinase and aggrecanase cleavage patterns. Evidence that matrix metalloproteinase cleavage interferes with aggrecanase activity.
Mercuri FA; Maciewicz RA; Tart J; Last K; Fosang AJ
J Biol Chem; 2000 Oct; 275(42):33038-45. PubMed ID: 11032846
[TBL] [Abstract][Full Text] [Related]
11. Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair.
Little CB; Meeker CT; Golub SB; Lawlor KE; Farmer PJ; Smith SM; Fosang AJ
J Clin Invest; 2007 Jun; 117(6):1627-36. PubMed ID: 17510707
[TBL] [Abstract][Full Text] [Related]
12. The interglobular domain of cartilage aggrecan is cleaved by hemorrhagic metalloproteinase HT-d (atrolysin C) at the matrix metalloproteinase and aggrecanase sites.
Tortorella MD; Pratta MA; Fox JW; Arner EC
J Biol Chem; 1998 Mar; 273(10):5846-50. PubMed ID: 9488721
[TBL] [Abstract][Full Text] [Related]
13. Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration.
Janusz MJ; Little CB; King LE; Hookfin EB; Brown KK; Heitmeyer SA; Caterson B; Poole AR; Taiwo YO
Osteoarthritis Cartilage; 2004 Sep; 12(9):720-8. PubMed ID: 15325638
[TBL] [Abstract][Full Text] [Related]
14. Generation and novel distribution of matrix metalloproteinase-derived aggrecan fragments in porcine cartilage explants.
Fosang AJ; Last K; Stanton H; Weeks DB; Campbell IK; Hardingham TE; Hembry RM
J Biol Chem; 2000 Oct; 275(42):33027-37. PubMed ID: 10882746
[TBL] [Abstract][Full Text] [Related]
15. Effects of ceramide on aggrecanase activity in rabbit articular cartilage.
Sabatini M; Thomas M; Deschamps C; Lesur C; Rolland G; de Nanteuil G; Bonnet J
Biochem Biophys Res Commun; 2001 May; 283(5):1105-10. PubMed ID: 11355886
[TBL] [Abstract][Full Text] [Related]
16. Analysis of Aggrecanase Activity Using Neoepitope Antibodies.
Santamaria S; Yamamoto K
Methods Mol Biol; 2020; 2043():125-136. PubMed ID: 31463908
[TBL] [Abstract][Full Text] [Related]
17. Development and characterization of a novel ELISA based assay for the quantitation of sub-nanomolar levels of neoepitope exposed NITEGE-containing aggrecan fragments.
Carter QL; Dotzlaf J; Swearingen C; Brittain I; Chambers M; Duffin K; Mitchell P; Thirunavukkarasu K
J Immunol Methods; 2007 Dec; 328(1-2):162-8. PubMed ID: 17942111
[TBL] [Abstract][Full Text] [Related]
18. Kinetics of aggrecanase- and metalloproteinase-induced neoepitopes in various stages of cartilage destruction in murine arthritis.
van Meurs JB; van Lent PL; Holthuysen AE; Singer II; Bayne EK; van den Berg WB
Arthritis Rheum; 1999 Jun; 42(6):1128-39. PubMed ID: 10366105
[TBL] [Abstract][Full Text] [Related]
19. Recombinant human aggrecan G1-G2 exhibits native binding properties and substrate specificity for matrix metalloproteinases and aggrecanase.
Mercuri FA; Doege KJ; Arner EC; Pratta MA; Last K; Fosang AJ
J Biol Chem; 1999 Nov; 274(45):32387-95. PubMed ID: 10542281
[TBL] [Abstract][Full Text] [Related]
20. Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.
Boeuf S; Graf F; Fischer J; Moradi B; Little CB; Richter W
Eur Cell Mater; 2012 May; 23():320-32. PubMed ID: 22562232
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
