BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

95 related articles for article (PubMed ID: 20137929)

  • 1. Exploration of a new series of PAR1 antagonists.
    Planty B; Pujol C; Lamothe M; Maraval C; Horn C; Le Grand B; Perez M
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1735-9. PubMed ID: 20137929
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and synthesis of a novel series of quinoline-based thrombin receptor (PAR-1) antagonists.
    Clasby MC; Chackalamannil S; Czarniecki M; Doller D; Eagen K; Greenlee WJ; Lin Y; Tsai H; Xia Y; Ahn HS; Agans-Fantuzzi J; Boykow G; Chintala M; Foster C; Bryant M; Lau J
    Bioorg Med Chem Lett; 2006 Mar; 16(6):1544-8. PubMed ID: 16380251
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Part II: piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.
    Parlow JJ; Burney MW; Case BL; Girard TJ; Hall KA; Harris PK; Hiebsch RR; Huff RM; Lachance RM; Mischke DA; Rapp SR; Woerndle RS; Ennis MD
    Bioorg Med Chem Lett; 2010 Feb; 20(4):1388-94. PubMed ID: 20097563
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of potent orally active thrombin receptor (protease activated receptor 1) antagonists as novel antithrombotic agents.
    Chackalamannil S; Xia Y; Greenlee WJ; Clasby M; Doller D; Tsai H; Asberom T; Czarniecki M; Ahn HS; Boykow G; Foster C; Agans-Fantuzzi J; Bryant M; Lau J; Chintala M
    J Med Chem; 2005 Sep; 48(19):5884-7. PubMed ID: 16161991
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring.
    Ueno H; Yokota K; Hoshi J; Yasue K; Hayashi M; Hase Y; Uchida I; Aisaka K; Katoh S; Cho H
    J Med Chem; 2005 May; 48(10):3586-604. PubMed ID: 15887966
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel protease activated receptors 1 antagonists with potent antithrombotic activity in vivo.
    Perez M; Lamothe M; Maraval C; Mirabel E; Loubat C; Planty B; Horn C; Michaux J; Marrot S; Letienne R; Pignier C; Bocquet A; Nadal-Wollbold F; Cussac D; de Vries L; Le Grand B
    J Med Chem; 2009 Oct; 52(19):5826-36. PubMed ID: 19791800
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antithrombotic activity of F 16618, a new PAR1 antagonist evaluated in extracorporeal arterio-venous shunt in the rat.
    Létienne R; Leparq-Panissié A; Calmettes Y; Nadal-Wollbold F; Perez M; Le Grand B
    Biochem Pharmacol; 2010 Jun; 79(11):1616-21. PubMed ID: 20188709
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thrombin receptor (protease activated receptor-1) antagonists as potent antithrombotic agents with strong antiplatelet effects.
    Chackalamannil S
    J Med Chem; 2006 Sep; 49(18):5389-403. PubMed ID: 16942011
    [No Abstract]   [Full Text] [Related]  

  • 9. Discovery and SAR of small molecule PAR1 antagonists.
    Rilatt I; Mirabel E; Le Grand B; Perez M
    Bioorg Med Chem Lett; 2010 Feb; 20(3):903-6. PubMed ID: 20042334
    [TBL] [Abstract][Full Text] [Related]  

  • 10. II. SAR studies of pyridyl-piperazinyl-piperidine derivatives as CXCR3 chemokine antagonists.
    Shao Y; Anilkumar GN; Carroll CD; Dong G; Hall JW; Hobbs DW; Jiang Y; Jenh CH; Kim SH; Kozlowski JA; McGuinness BF; Rosenblum SB; Schulman I; Shih NY; Shu Y; Wong MK; Yu W; Zawacki LG; Zeng Q
    Bioorg Med Chem Lett; 2011 Mar; 21(5):1527-31. PubMed ID: 21277198
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PAR1 antagonist mediated antithrombotic activity in extracorporeal arterio-venous shunt in the rat.
    Létienne R; Leparq-Panissié A; Bocquet A; Calmettes Y; Culié C; Le Grand B
    Thromb Res; 2010 Mar; 125(3):257-61. PubMed ID: 19476974
    [No Abstract]   [Full Text] [Related]  

  • 12. Guanidine derivatives as combined thromboxane A2 receptor antagonists and synthase inhibitors.
    Soyka R; Guth BD; Weisenberger HM; Luger P; Müller TH
    J Med Chem; 1999 Apr; 42(7):1235-49. PubMed ID: 10197967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as a potent and long-acting antithrombotic agent.
    Badorc A; Bordes MF; de Cointet P; Savi P; Bernat A; Lalé A; Petitou M; Maffrand JP; Herbert JM
    J Med Chem; 1997 Oct; 40(21):3393-401. PubMed ID: 9341914
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heterotricyclic himbacine analogs as potent, orally active thrombin receptor (protease activated receptor-1) antagonists.
    Chelliah MV; Chackalamannil S; Xia Y; Eagen K; Clasby MC; Gao X; Greenlee W; Ahn HS; Agans-Fantuzzi J; Boykow G; Hsieh Y; Bryant M; Palamanda J; Chan TM; Hesk D; Chintala M
    J Med Chem; 2007 Oct; 50(21):5147-60. PubMed ID: 17854166
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel derivatives of 2-pyridinemethylamine as selective, potent, and orally active agonists at 5-HT1A receptors.
    Vacher B; Bonnaud B; Funes P; Jubault N; Koek W; Assié MB; Cosi C; Kleven M
    J Med Chem; 1999 May; 42(9):1648-60. PubMed ID: 10229633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of 2-(phenoxypyridine)-3-phenylureas as small molecule P2Y1 antagonists.
    Chao H; Turdi H; Herpin TF; Roberge JY; Liu Y; Schnur DM; Poss MA; Rehfuss R; Hua J; Wu Q; Price LA; Abell LM; Schumacher WA; Bostwick JS; Steinbacher TE; Stewart AB; Ogletree ML; Huang CS; Chang M; Cacace AM; Arcuri MJ; Celani D; Wexler RR; Lawrence RM
    J Med Chem; 2013 Feb; 56(4):1704-14. PubMed ID: 23368907
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation.
    Parlow JJ; Burney MW; Case BL; Girard TJ; Hall KA; Hiebsch RR; Huff RM; Lachance RM; Mischke DA; Rapp SR; Woerndle RS; Ennis MD
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6148-56. PubMed ID: 19796941
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xa inhibitors.
    Phillips G; Davey DD; Eagen KA; Koovakkat SK; Liang A; Ng HP; Pinkerton M; Trinh L; Whitlow M; Beatty AM; Morrissey MM
    J Med Chem; 1999 May; 42(10):1749-56. PubMed ID: 10346927
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of diarylurea P2Y(1) antagonists with improved aqueous solubility.
    Wang TC; Qiao JX; Clark CG; Jua J; Price LA; Wu Q; Chang M; Zheng J; Huang CS; Everlof G; Schumacher WA; Wong PC; Seiffert DA; Stewart AB; Bostwick JS; Crain EJ; Watson CA; Rehfuss R; Wexler RR; Lam PY
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3239-43. PubMed ID: 23602442
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex.
    Kohrt JT; Filipski KJ; Cody WL; Cai C; Dudley DA; Van Huis CA; Willardsen JA; Rapundalo ST; Saiya-Cork K; Leadley RJ; Narasimhan L; Zhang E; Whitlow M; Adler M; McLean K; Chou YL; McKnight C; Arnaiz DO; Shaw KJ; Light DR; Edmunds JJ
    Bioorg Med Chem Lett; 2005 Nov; 15(21):4752-6. PubMed ID: 16125385
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.