316 related articles for article (PubMed ID: 20138760)
1. Novel 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one derivatives as potential anti-cancer agents.
Devegowda VN; Kim JH; Han KC; Yang EG; Choo H; Pae AN; Nam G; Choi KI
Bioorg Med Chem Lett; 2010 Mar; 20(5):1630-3. PubMed ID: 20138760
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and anti-tumor activities of novel pyrazolo[1,5-a]pyrimidines.
Li J; Zhao YF; Zhao XL; Yuan XY; Gong P
Arch Pharm (Weinheim); 2006 Nov; 339(11):593-7. PubMed ID: 17036367
[TBL] [Abstract][Full Text] [Related]
3. Anti-cancer activities of 5-acyl-6-[2-hydroxy/benzyloxy-3-(amino)-propylamino]-1,3-dialkyl-1H-pyrimidin-2,4-diones.
Singh P; Paul K
Bioorg Med Chem; 2006 Dec; 14(24):8622-5. PubMed ID: 16949293
[TBL] [Abstract][Full Text] [Related]
4. Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.
Carraro F; Pucci A; Naldini A; Schenone S; Bruno O; Ranise A; Bondavalli F; Brullo C; Fossa P; Menozzi G; Mosti L; Manetti F; Botta M
J Med Chem; 2004 Mar; 47(7):1595-8. PubMed ID: 15027847
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and anti-tumor activities of some new pyridines and pyrazolo[1,5-a]pyrimidines.
Ahmed OM; Mohamed MA; Ahmed RR; Ahmed SA
Eur J Med Chem; 2009 Sep; 44(9):3519-23. PubMed ID: 19398146
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of novel pyrazoles and pyrazolo[3,4-d]pyrimidines incorporating a benzenesulfonamide moiety.
Ashour HM; Wahab AE
Arch Pharm (Weinheim); 2009 Apr; 342(4):238-52. PubMed ID: 19340837
[TBL] [Abstract][Full Text] [Related]
7. One pot synthesis of thiazolodihydropyrimidinones and evaluation of their anticancer activity.
Holla BS; Rao BS; Sarojini BK; Akberali PM
Eur J Med Chem; 2004 Sep; 39(9):777-83. PubMed ID: 15337290
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, docking and antitumor activity of quinazolino [3, 4-a] thieno [3, 2-d] pyrimidin-8-one derivatives.
Zheng Y; Wu X; Xue B; Li M; Ji M
Chem Biol Drug Des; 2010 Sep; 76(3):285-90. PubMed ID: 20604799
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and antitumor activity of novel 6-aryl and 6-alkylpyrazolo[3,4-d]pyrimidin-4-one derivatives.
el-Enany MM; Kamel MM; Khalil OM; el-Nassan HB
Eur J Med Chem; 2010 Nov; 45(11):5286-91. PubMed ID: 20846758
[TBL] [Abstract][Full Text] [Related]
10. Pyrimidines. Part II: Synthesis of novel pyrimidines, 1,2,4-triazolo[4,3-a]pyrimidin-7-ones and pyrimidino[2,1-c][1,2,4]triazin-8-ones for their antimicrobial and anticancer activities.
Habib NS; Soliman R; Ismail K; Hassan AM; Sarg MT
Boll Chim Farm; 2003 Nov; 142(9):396-405. PubMed ID: 14971308
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and antitumor activity of novel pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-one derivatives.
El-Nassan HB
Eur J Med Chem; 2011 Jun; 46(6):2031-6. PubMed ID: 21429629
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of N-{4-[(2,4-diamino-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid and N-{4-[(2-amino-4-oxo-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid as dual inhibitors of dihydrofolate reductase and thymidylate synthase and as potential antitumor agents.
Gangjee A; Lin X; Kisliuk RL; McGuire JJ
J Med Chem; 2005 Nov; 48(23):7215-22. PubMed ID: 16279780
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of novel 2,4,5-substituted pyrimidine derivatives for anticancer activity.
Xie F; Zhao H; Zhao L; Lou L; Hu Y
Bioorg Med Chem Lett; 2009 Jan; 19(1):275-8. PubMed ID: 19028425
[TBL] [Abstract][Full Text] [Related]
14. Rational design, synthesis, and biological evaluation of bis(pyrimido[5,6,1-de]acridines) and bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as new anticancer agents.
Antonini I; Polucci P; Magnano A; Sparapani S; Martelli S
J Med Chem; 2004 Oct; 47(21):5244-50. PubMed ID: 15456268
[TBL] [Abstract][Full Text] [Related]
15. Preparation of 3-substituted-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amines as RET kinase inhibitors.
Dinér P; Alao JP; Söderlund J; Sunnerhagen P; Grøtli M
J Med Chem; 2012 May; 55(10):4872-6. PubMed ID: 22559926
[TBL] [Abstract][Full Text] [Related]
16. Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines.
Manetti F; Brullo C; Magnani M; Mosci F; Chelli B; Crespan E; Schenone S; Naldini A; Bruno O; Trincavelli ML; Maga G; Carraro F; Martini C; Bondavalli F; Botta M
J Med Chem; 2008 Mar; 51(5):1252-9. PubMed ID: 18257513
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of some pyrazolines and pyrimidines derived from polymethoxy chalcones as anticancer and antimicrobial agents.
Rostom SA; Badr MH; Abd El Razik HA; Ashour HM; Abdel Wahab AE
Arch Pharm (Weinheim); 2011 Sep; 344(9):572-87. PubMed ID: 21755528
[TBL] [Abstract][Full Text] [Related]
18. 2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity.
Klutchko SR; Hamby JM; Boschelli DH; Wu Z; Kraker AJ; Amar AM; Hartl BG; Shen C; Klohs WD; Steinkampf RW; Driscoll DL; Nelson JM; Elliott WL; Roberts BJ; Stoner CL; Vincent PW; Dykes DJ; Panek RL; Lu GH; Major TC; Dahring TK; Hallak H; Bradford LA; Showalter HD; Doherty AM
J Med Chem; 1998 Aug; 41(17):3276-92. PubMed ID: 9703473
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of 2,4,6-functionalized derivatives of pyrido[2,3-d]pyrimidines as cytotoxic agents and apoptosis inducers.
Sanmartín C; Domínguez MV; Cordeu L; Cubedo E; García-Foncillas J; Font M; Palop JA
Arch Pharm (Weinheim); 2008 Jan; 341(1):28-41. PubMed ID: 18161903
[TBL] [Abstract][Full Text] [Related]
20. Synthesis, anticancer and radioprotective activities of some new pyrazolo[3,4-d]pyrimidines containing amino acid moieties.
Ghorab MM; Ragab FA; Noaman E; Heiba HI; Aboulmagd SA
Arzneimittelforschung; 2009; 59(2):96-103. PubMed ID: 19338140
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
