214 related articles for article (PubMed ID: 2014216)
1. Oral absorption of peptides: influence of pH and inhibitors on the intestinal hydrolysis of leu-enkephalin and analogues.
Friedman DI; Amidon GL
Pharm Res; 1991 Jan; 8(1):93-6. PubMed ID: 2014216
[TBL] [Abstract][Full Text] [Related]
2. Transdermal delivery of bioactive peptides: the effect of n-decylmethyl sulfoxide, pH, and inhibitors on enkephalin metabolism and transport.
Choi HK; Flynn GL; Amidon GL
Pharm Res; 1990 Nov; 7(11):1099-106. PubMed ID: 2293206
[TBL] [Abstract][Full Text] [Related]
3. An in vitro evaluation of metabolism and poor membrane permeation impeding intestinal absorption of leucine enkephalin, and methods to increase absorption.
Aungst BJ; Blake JA; Hussain MA
J Pharmacol Exp Ther; 1991 Oct; 259(1):139-45. PubMed ID: 1920113
[TBL] [Abstract][Full Text] [Related]
4. Effects of three peptidase inhibitors, amastatin, captopril and phosphoramidon, on the hydrolysis of [Met5]-enkephalin-Arg6-Phe7 and other opioid peptides.
Hiranuma T; Kitamura K; Taniguchi T; Kobayashi T; Tamaki R; Kanai M; Akahori K; Iwao K; Oka T
Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar; 357(3):276-82. PubMed ID: 9550299
[TBL] [Abstract][Full Text] [Related]
5. Identification and characterization of aminopeptidases from Aplysia californica.
Bawab W; Querido E; Crine P; DesGroseillers L
Biochem J; 1992 Sep; 286 ( Pt 3)(Pt 3):967-75. PubMed ID: 1417757
[TBL] [Abstract][Full Text] [Related]
6. Effects of various protease inhibitors on the stability and permeability of [D-Ala2,D-Leu5]enkephalin in the rat intestine: comparison with leucine enkephalin.
Uchiyama T; Kotani A; Kishida T; Tatsumi H; Okamoto A; Fujita T; Murakami M; Muranishi S; Yamamoto A
J Pharm Sci; 1998 Apr; 87(4):448-52. PubMed ID: 9548897
[TBL] [Abstract][Full Text] [Related]
7. Rat jejunal permeability and metabolism of mu-selective tetrapeptides in gastrointestinal fluids from humans and rats.
Krondahl E; Orzechowski A; Ekström G; Lennernäs H
Pharm Res; 1997 Dec; 14(12):1780-5. PubMed ID: 9453068
[TBL] [Abstract][Full Text] [Related]
8. Intestinal assimilation of a tetrapeptide in the rat. Obligate function of brush border aminopeptidase.
Smithson KW; Gray GM
J Clin Invest; 1977 Sep; 60(3):665-74. PubMed ID: 893670
[TBL] [Abstract][Full Text] [Related]
9. Effects of peptidase inhibitors on the [Met5]-enkephalin hydrolysis in ileal and striatal preparations of guinea-pig: almost complete protection of degradation by the combination of amastatin, captopril and thiorphan.
Hiranuma T; Oka T
Jpn J Pharmacol; 1986 Aug; 41(4):437-46. PubMed ID: 3534399
[TBL] [Abstract][Full Text] [Related]
10. Hepatic inactivation of Leu-enkephalin.
MacKinnon KL; Zuzel KA; Billington D
Regul Pept; 1996 Dec; 67(2):85-92. PubMed ID: 8958578
[TBL] [Abstract][Full Text] [Related]
11. Further characterization of the in vitro hydrolysis of [Leu]- and [Met]enkephalin in rat plasma: HPLC-ECD measurement of substrate and metabolite concentrations.
Shibanoki S; Weinberger SB; Ishikawa K; Martinez JL
Regul Pept; 1991 Feb; 32(3):267-78. PubMed ID: 1678195
[TBL] [Abstract][Full Text] [Related]
12. Development of novel lipophilic derivatives of DADLE (leucine enkephalin analogue): intestinal permeability characateristics of DADLE derivatives in rats.
Uchiyama T; Kotani A; Tatsumi H; Kishida T; Okamoto A; Okada N; Murakami M; Fujita T; Fujiwara Y; Kiso Y; Muranishi S; Yamamoto A
Pharm Res; 2000 Dec; 17(12):1461-7. PubMed ID: 11303954
[TBL] [Abstract][Full Text] [Related]
13. Hydrolysis of leucine enkephalin in the nasal cavity of the rat--a possible factor in the low bioavailability of nasally administered peptides.
Hussain A; Faraj J; Aramaki Y; Truelove JE
Biochem Biophys Res Commun; 1985 Dec; 133(3):923-8. PubMed ID: 4084310
[TBL] [Abstract][Full Text] [Related]
14. Degradation of low-molecular-weight opioid peptides by vascular plasma membrane aminopeptidase M.
Bausback HH; Ward PE
Biochim Biophys Acta; 1986 Jul; 882(3):437-44. PubMed ID: 2873842
[TBL] [Abstract][Full Text] [Related]
15. Protection against dynorphin-(1-8) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon.
Hiranuma T; Kitamura K; Taniguchi T; Kanai M; Arai Y; Iwao K; Oka T
J Pharmacol Exp Ther; 1998 Aug; 286(2):863-9. PubMed ID: 9694943
[TBL] [Abstract][Full Text] [Related]
16. Pulmonary metabolism of exogenous enkephalins in isolated perfused rat lungs.
Gillespie MN; Krechniak JW; Crooks PA; Altiere RJ; Olson JW
J Pharmacol Exp Ther; 1985 Mar; 232(3):675-81. PubMed ID: 2983067
[TBL] [Abstract][Full Text] [Related]
17. Metabolism of enkephalins in head membranes of the leech Theromyzon tessulatum by peptidases: isolation of an enkephalin-degrading aminopeptidase.
Laurent V; Salzet M
Regul Pept; 1996 Sep; 65(2):123-31. PubMed ID: 8884979
[TBL] [Abstract][Full Text] [Related]
18. Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli.
Matsas R; Fulcher IS; Kenny AJ; Turner AJ
Proc Natl Acad Sci U S A; 1983 May; 80(10):3111-5. PubMed ID: 6190172
[TBL] [Abstract][Full Text] [Related]
19. Transport kinetics of leucine enkephalin across Caco-2 monolayers: quantitative analysis for contribution of enzymatic and transport barrier.
Quan YS; Fujita T; Tohara D; Tsuji M; Kohyama M; Yamamoto A
Life Sci; 1999; 64(14):1243-52. PubMed ID: 10210267
[TBL] [Abstract][Full Text] [Related]
20. Intestinal metabolism and absorption of cholecystokinin analogs in rats.
Su SF; Amidon GL; Lee HJ
Biochem Biophys Res Commun; 2002 Apr; 292(3):632-8. PubMed ID: 11922613
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
