These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1011 related articles for article (PubMed ID: 20142433)

  • 21. The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.
    Bleeker FE; Atai NA; Lamba S; Jonker A; Rijkeboer D; Bosch KS; Tigchelaar W; Troost D; Vandertop WP; Bardelli A; Van Noorden CJ
    Acta Neuropathol; 2010 Apr; 119(4):487-94. PubMed ID: 20127344
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Isocitrate dehydrogenase mutations in gliomas.
    Waitkus MS; Diplas BH; Yan H
    Neuro Oncol; 2016 Jan; 18(1):16-26. PubMed ID: 26188014
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Preclinical Drug Metabolism, Pharmacokinetic, and Pharmacodynamic Profiles of Ivosidenib, an Inhibitor of Mutant Isocitrate Dehydrogenase 1 for Treatment of Isocitrate Dehydrogenase 1-Mutant Malignancies.
    Chen Y; Nagaraja NV; Fan B; Utley L; Lemieux RM; Popovici-Muller J; Dang L; Kim H; Yan L; Su SM; Biller SA; Yang H
    Drug Metab Dispos; 2021 Oct; 49(10):870-881. PubMed ID: 34321251
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism.
    Wen H; Cho HR; Yun T; Kim H; Park CK; Lee SH; Choi SH; Park S
    J Neurochem; 2015 Jan; 132(2):183-93. PubMed ID: 25251602
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Establishment of a multi-specific monoclonal antibody MsMab-1 recognizing both IDH1 and IDH2 mutations.
    Kato Kaneko M; Ogasawara S; Kato Y
    Tohoku J Exp Med; 2013 Jun; 230(2):103-9. PubMed ID: 23782684
    [TBL] [Abstract][Full Text] [Related]  

  • 26. IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain.
    Lopez GY; Reitman ZJ; Solomon D; Waldman T; Bigner DD; McLendon RE; Rosenberg SA; Samuels Y; Yan H
    Biochem Biophys Res Commun; 2010 Jul; 398(3):585-7. PubMed ID: 20603105
    [TBL] [Abstract][Full Text] [Related]  

  • 27. IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma.
    Lu J; Xu L; Zou Y; Yang RX; Fan Y; Zhang W; Yu D; Yao YG
    Med Sci Monit; 2014 Feb; 20():247-54. PubMed ID: 24531386
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Isocitrate dehydrogenase variants in cancer - Cellular consequences and therapeutic opportunities.
    Liu S; Cadoux-Hudson T; Schofield CJ
    Curr Opin Chem Biol; 2020 Aug; 57():122-134. PubMed ID: 32777735
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Gaining Insight into the Catalytic Mechanism of the R132H IDH1 Mutant: A Synergistic DFT Cluster and Experimental Investigation.
    Broome JA; Nguyen NP; Baumung CRE; Chen VC; Bushnell EAC
    Biochemistry; 2024 Oct; 63(20):2682-2691. PubMed ID: 39318042
    [TBL] [Abstract][Full Text] [Related]  

  • 30. IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication.
    Paschka P; Schlenk RF; Gaidzik VI; Habdank M; Krönke J; Bullinger L; Späth D; Kayser S; Zucknick M; Götze K; Horst HA; Germing U; Döhner H; Döhner K
    J Clin Oncol; 2010 Aug; 28(22):3636-43. PubMed ID: 20567020
    [TBL] [Abstract][Full Text] [Related]  

  • 31. IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives.
    Yang H; Ye D; Guan KL; Xiong Y
    Clin Cancer Res; 2012 Oct; 18(20):5562-71. PubMed ID: 23071358
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Biological Significance of Mutant Isocitrate Dehydrogenase 1 and 2 in Gliomagenesis.
    Ohba S; Hirose Y
    Neurol Med Chir (Tokyo); 2016; 56(4):170-9. PubMed ID: 26960449
    [TBL] [Abstract][Full Text] [Related]  

  • 33. IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders.
    Zou Y; Zeng Y; Zhang DF; Zou SH; Cheng YF; Yao YG
    Biochem Biophys Res Commun; 2010 Nov; 402(2):378-83. PubMed ID: 20946881
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.
    Navis AC; Niclou SP; Fack F; Stieber D; van Lith S; Verrijp K; Wright A; Stauber J; Tops B; Otte-Holler I; Wevers RA; van Rooij A; Pusch S; von Deimling A; Tigchelaar W; van Noorden CJ; Wesseling P; Leenders WP
    Acta Neuropathol Commun; 2013 May; 1():18. PubMed ID: 24252742
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China.
    Wang JH; Chen WL; Li JM; Wu SF; Chen TL; Zhu YM; Zhang WN; Li Y; Qiu YP; Zhao AH; Mi JQ; Jin J; Wang YG; Ma QL; Huang H; Wu DP; Wang QR; Li Y; Yan XJ; Yan JS; Li JY; Wang S; Huang XJ; Wang BS; Jia W; Shen Y; Chen Z; Chen SJ
    Proc Natl Acad Sci U S A; 2013 Oct; 110(42):17017-22. PubMed ID: 24082129
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency.
    Avellaneda Matteo D; Grunseth AJ; Gonzalez ER; Anselmo SL; Kennedy MA; Moman P; Scott DA; Hoang A; Sohl CD
    J Biol Chem; 2017 May; 292(19):7971-7983. PubMed ID: 28330869
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Aberrant HIF1- α and SIX-1 Expression is Associated with Poor Prognosis in Acute Myeloid Leukemia Patients with Isocitrate Dehydrogenase 1 Mutations.
    Ali T; Usman R; Shah SA; Parvez A; Anwar S; Muneer Z; Saeed M
    Cancer Control; 2024; 31():10732748241271714. PubMed ID: 39110525
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Development of Novel Therapeutics Targeting Isocitrate Dehydrogenase Mutations in Cancer.
    Sharma H
    Curr Top Med Chem; 2018; 18(6):505-524. PubMed ID: 29773061
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Water Networks and Correlated Motions in Mutant Isocitrate Dehydrogenase 1 (IDH1) Are Critical for Allosteric Inhibitor Binding and Activity.
    Chambers JM; Miller W; Quichocho G; Upadhye V; Matteo DA; Bobkov AA; Sohl CD; Schiffer JM
    Biochemistry; 2020 Feb; 59(4):479-490. PubMed ID: 31869219
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.
    Seltzer MJ; Bennett BD; Joshi AD; Gao P; Thomas AG; Ferraris DV; Tsukamoto T; Rojas CJ; Slusher BS; Rabinowitz JD; Dang CV; Riggins GJ
    Cancer Res; 2010 Nov; 70(22):8981-7. PubMed ID: 21045145
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 51.