BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

71 related articles for article (PubMed ID: 20145262)

  • 1. Pharmacokinetics, pharmacodynamics, and metabolism of triethylenetetramine in healthy human participants: an open-label trial.
    Lu J; Poppitt SD; Othman AA; Sunderland T; Ruggiero K; Willett MS; Diamond LE; Garcia WD; Roesch BG; Cooper GJ
    J Clin Pharmacol; 2010 Jun; 50(6):647-58. PubMed ID: 20145262
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Triethylenetetramine and metabolites: levels in relation to copper and zinc excretion in urine of healthy volunteers and type 2 diabetic patients.
    Lu J; Chan YK; Gamble GD; Poppitt SD; Othman AA; Cooper GJ
    Drug Metab Dispos; 2007 Feb; 35(2):221-7. PubMed ID: 17108057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetic and pharmacodynamic modeling of a copper-selective chelator (TETA) in healthy adults.
    Cho HY; Blum RA; Sunderland T; Cooper GJ; Jusko WJ
    J Clin Pharmacol; 2009 Aug; 49(8):916-28. PubMed ID: 19602718
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS).
    Lu J; Chan YK; Poppitt SD; Cooper GJ
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Nov; 859(1):62-8. PubMed ID: 17901001
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development and validation of a rapid HPLC method for the simultaneous determination of triethylenetetramine and its two main metabolites in human serum.
    Othman A; Lu J; Sunderland T; Cooper GJ
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Dec; 860(1):42-8. PubMed ID: 17980682
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Urinary acetylated metabolites and N-acetyltransferase-2 genotype in human subjects treated with a para-phenylenediamine-containing oxidative hair dye.
    Nohynek GJ; Skare JA; Meuling WJ; Hein DW; De Bie AT; Toutain H
    Food Chem Toxicol; 2004 Nov; 42(11):1885-91. PubMed ID: 15350687
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Complex formation equilibria of Cu(II) and Zn(II) with triethylenetetramine and its mono- and di-acetyl metabolites.
    Nurchi VM; Crisponi G; Crespo-Alonso M; Lachowicz JI; Szewczuk Z; Cooper GJ
    Dalton Trans; 2013 May; 42(17):6161-70. PubMed ID: 23202417
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantitative proteomic profiling identifies new renal targets of copper(II)-selective chelation in the reversal of diabetic nephropathy in rats.
    Gong D; Chen X; Middleditch M; Huang L; Vazhoor Amarsingh G; Reddy S; Lu J; Zhang S; Ruggiero K; Phillips AR; Cooper GJ
    Proteomics; 2009 Sep; 9(18):4309-20. PubMed ID: 19634143
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tetramine cupruretic agents: a comparison in dogs.
    Allen KG; Twedt DC; Hunsaker HA
    Am J Vet Res; 1987 Jan; 48(1):28-30. PubMed ID: 3826839
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triethylenetetramine pharmacology and its clinical applications.
    Lu J
    Mol Cancer Ther; 2010 Sep; 9(9):2458-67. PubMed ID: 20660601
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolism of triethylenetetramine and 1,12-diamino-3,6,9-triazadodecane by the spermidine/spermine-N(1)-acetyltransferase and thialysine acetyltransferase.
    Hyvönen MT; Weisell J; Khomutov AR; Alhonen L; Vepsäläinen J; Keinänen TA
    Drug Metab Dispos; 2013 Jan; 41(1):30-2. PubMed ID: 23024204
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Colorectal adenomatous and hyperplastic polyps: smoking and N-acetyltransferase 2 polymorphisms.
    Potter JD; Bigler J; Fosdick L; Bostick RM; Kampman E; Chen C; Louis TA; Grambsch P
    Cancer Epidemiol Biomarkers Prev; 1999 Jan; 8(1):69-75. PubMed ID: 9950242
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-acetyltransferase 2 polymorphism in patients with diabetes mellitus.
    Yalin S; Hatungil R; Tamer L; Ates NA; Dogruer N; Yildirim H; Karakas S; Atik U
    Cell Biochem Funct; 2007; 25(4):407-11. PubMed ID: 16397907
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities.
    McQuilkin SH; Nierenberg DW; Bresnick E
    Cancer Epidemiol Biomarkers Prev; 1995 Mar; 4(2):139-46. PubMed ID: 7742721
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats.
    Gong D; Lu J; Chen X; Choong SY; Zhang S; Chan YK; Glyn-Jones S; Gamble GD; Phillips AR; Cooper GJ
    Mol Pharmacol; 2006 Dec; 70(6):2045-51. PubMed ID: 16973718
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-acetylation among HIV-positive patients and patients with AIDS: when is fast, fast and slow, slow?
    O'Neil WM; Gilfix BM; DiGirolamo A; Tsoukas CM; Wainer IW
    Clin Pharmacol Ther; 1997 Sep; 62(3):261-71. PubMed ID: 9333101
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Urinary copper excretion from rats following administration of aliphatic and alicyclic polyamines (author's transl)].
    Harders H; Armah B; Cohnen E; Führ J; Heinz N; Schröder HF
    Arzneimittelforschung; 1980; 30(2):254-8. PubMed ID: 7378100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Copper(II)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments.
    Lu J; Gong D; Choong SY; Xu H; Chan YK; Chen X; Fitzpatrick S; Glyn-Jones S; Zhang S; Nakamura T; Ruggiero K; Obolonkin V; Poppitt SD; Phillips AR; Cooper GJ
    Diabetologia; 2010 Jun; 53(6):1217-26. PubMed ID: 20221822
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk.
    Le Marchand L; Hankin JH; Wilkens LR; Pierce LM; Franke A; Kolonel LN; Seifried A; Custer LJ; Chang W; Lum-Jones A; Donlon T
    Cancer Epidemiol Biomarkers Prev; 2001 Dec; 10(12):1259-66. PubMed ID: 11751443
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutic potential of copper chelation with triethylenetetramine in managing diabetes mellitus and Alzheimer's disease.
    Cooper GJ
    Drugs; 2011 Jul; 71(10):1281-320. PubMed ID: 21770477
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.