254 related articles for article (PubMed ID: 20149667)
1. Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases.
Alptüzün V; Prinz M; Hörr V; Scheiber J; Radacki K; Fallarero A; Vuorela P; Engels B; Braunschweig H; Erciyas E; Holzgrabe U
Bioorg Med Chem; 2010 Mar; 18(5):2049-59. PubMed ID: 20149667
[TBL] [Abstract][Full Text] [Related]
2. Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation.
Belluti F; Rampa A; Piazzi L; Bisi A; Gobbi S; Bartolini M; Andrisano V; Cavalli A; Recanatini M; Valenti P
J Med Chem; 2005 Jun; 48(13):4444-56. PubMed ID: 15974596
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase.
Huang L; Luo Z; He F; Lu J; Li X
Bioorg Med Chem; 2010 Jun; 18(12):4475-84. PubMed ID: 20471843
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and evaluation of flavonoid derivatives as potent AChE inhibitors.
Sheng R; Lin X; Zhang J; Chol KS; Huang W; Yang B; He Q; Hu Y
Bioorg Med Chem; 2009 Sep; 17(18):6692-8. PubMed ID: 19692250
[TBL] [Abstract][Full Text] [Related]
5. Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity.
Rizzo S; Rivière C; Piazzi L; Bisi A; Gobbi S; Bartolini M; Andrisano V; Morroni F; Tarozzi A; Monti JP; Rampa A
J Med Chem; 2008 May; 51(10):2883-6. PubMed ID: 18419109
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
Kwon YE; Park JY; No KT; Shin JH; Lee SK; Eun JS; Yang JH; Shin TY; Kim DK; Chae BS; Leem JY; Kim KH
Bioorg Med Chem; 2007 Oct; 15(20):6596-607. PubMed ID: 17681794
[TBL] [Abstract][Full Text] [Related]
7. Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Marco-Contelles J; León R; de los Ríos C; Samadi A; Bartolini M; Andrisano V; Huertas O; Barril X; Luque FJ; Rodríguez-Franco MI; López B; López MG; García AG; Carreiras Mdo C; Villarroya M
J Med Chem; 2009 May; 52(9):2724-32. PubMed ID: 19374444
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.
Muñoz-Ruiz P; Rubio L; García-Palomero E; Dorronsoro I; del Monte-Millán M; Valenzuela R; Usán P; de Austria C; Bartolini M; Andrisano V; Bidon-Chanal A; Orozco M; Luque FJ; Medina M; Martínez A
J Med Chem; 2005 Nov; 48(23):7223-33. PubMed ID: 16279781
[TBL] [Abstract][Full Text] [Related]
9. 1,4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood-brain barrier.
Prinz M; Parlar S; Bayraktar G; Alptüzün V; Erciyas E; Fallarero A; Karlsson D; Vuorela P; Burek M; Förster C; Turunc E; Armagan G; Yalcin A; Schiller C; Leuner K; Krug M; Sotriffer CA; Holzgrabe U
Eur J Pharm Sci; 2013 Jul; 49(4):603-13. PubMed ID: 23643737
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Bolea I; Juárez-Jiménez J; de Los Ríos C; Chioua M; Pouplana R; Luque FJ; Unzeta M; Marco-Contelles J; Samadi A
J Med Chem; 2011 Dec; 54(24):8251-70. PubMed ID: 22023459
[TBL] [Abstract][Full Text] [Related]
11. Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library.
Dickerson TJ; Beuscher AE; Rogers CJ; Hixon MS; Yamamoto N; Xu Y; Olson AJ; Janda KD
Biochemistry; 2005 Nov; 44(45):14845-53. PubMed ID: 16274232
[TBL] [Abstract][Full Text] [Related]
12. Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Camps P; Formosa X; Galdeano C; Gómez T; Muñoz-Torrero D; Scarpellini M; Viayna E; Badia A; Clos MV; Camins A; Pallàs M; Bartolini M; Mancini F; Andrisano V; Estelrich J; Lizondo M; Bidon-Chanal A; Luque FJ
J Med Chem; 2008 Jun; 51(12):3588-98. PubMed ID: 18517184
[TBL] [Abstract][Full Text] [Related]
13. 3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy.
Piazzi L; Rampa A; Bisi A; Gobbi S; Belluti F; Cavalli A; Bartolini M; Andrisano V; Valenti P; Recanatini M
J Med Chem; 2003 Jun; 46(12):2279-82. PubMed ID: 12773032
[TBL] [Abstract][Full Text] [Related]
14. Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Camps P; Formosa X; Galdeano C; Muñoz-Torrero D; Ramírez L; Gómez E; Isambert N; Lavilla R; Badia A; Clos MV; Bartolini M; Mancini F; Andrisano V; Arce MP; Rodríguez-Franco MI; Huertas O; Dafni T; Luque FJ
J Med Chem; 2009 Sep; 52(17):5365-79. PubMed ID: 19663388
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties.
Tumiatti V; Andrisano V; Banzi R; Bartolini M; Minarini A; Rosini M; Melchiorre C
J Med Chem; 2004 Dec; 47(26):6490-8. PubMed ID: 15588084
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors.
Huang L; Shi A; He F; Li X
Bioorg Med Chem; 2010 Feb; 18(3):1244-51. PubMed ID: 20056426
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues.
Bolognesi ML; Bartolini M; Cavalli A; Andrisano V; Rosini M; Minarini A; Melchiorre C
J Med Chem; 2004 Nov; 47(24):5945-52. PubMed ID: 15537349
[TBL] [Abstract][Full Text] [Related]
18. Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Brunhofer G; Fallarero A; Karlsson D; Batista-Gonzalez A; Shinde P; Gopi Mohan C; Vuorela P
Bioorg Med Chem; 2012 Nov; 20(22):6669-79. PubMed ID: 23062825
[TBL] [Abstract][Full Text] [Related]
19. Acetylcholinesterase inhibitors: synthesis and structure-activity relationships of omega-[N-methyl-N-(3-alkylcarbamoyloxyphenyl)- methyl]aminoalkoxyheteroaryl derivatives.
Rampa A; Bisi A; Valenti P; Recanatini M; Cavalli A; Andrisano V; Cavrini V; Fin L; Buriani A; Giusti P
J Med Chem; 1998 Oct; 41(21):3976-86. PubMed ID: 9767635
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush.
Rosini M; Simoni E; Bartolini M; Cavalli A; Ceccarini L; Pascu N; McClymont DW; Tarozzi A; Bolognesi ML; Minarini A; Tumiatti V; Andrisano V; Mellor IR; Melchiorre C
J Med Chem; 2008 Aug; 51(15):4381-4. PubMed ID: 18605718
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
