BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 20151404)

  • 1. The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
    Löffek S; Wöll S; Höhfeld J; Leube RE; Has C; Bruckner-Tuderman L; Magin TM
    Hum Mutat; 2010 Apr; 31(4):466-76. PubMed ID: 20151404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases.
    Chamcheu JC; Navsaria H; Pihl-Lundin I; Liovic M; Vahlquist A; Törmä H
    J Invest Dermatol; 2011 Aug; 131(8):1684-91. PubMed ID: 21490615
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex.
    Sørensen CB; Andresen BS; Jensen UB; Jensen TG; Jensen PK; Gregersen N; Bolund L
    Exp Dermatol; 2003 Aug; 12(4):472-9. PubMed ID: 12930305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of immortalized human epidermolysis bullosa simplex (KRT5) cell lines: trimethylamine N-oxide protects the keratin cytoskeleton against disruptive stress condition.
    Chamcheu JC; Lorié EP; Akgul B; Bannbers E; Virtanen M; Gammon L; Moustakas A; Navsaria H; Vahlquist A; Törmä H
    J Dermatol Sci; 2009 Mar; 53(3):198-206. PubMed ID: 19157792
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An autocrine/paracrine loop linking keratin 14 aggregates to tumor necrosis factor alpha-mediated cytotoxicity in a keratinocyte model of epidermolysis bullosa simplex.
    Yoneda K; Furukawa T; Zheng YJ; Momoi T; Izawa I; Inagaki M; Manabe M; Inagaki N
    J Biol Chem; 2004 Feb; 279(8):7296-303. PubMed ID: 14660619
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasome-mediated degradation of keratins 7, 8, 17 and 18 by mutant KLHL24 in a foetal keratinocyte model: Novel insight in congenital skin defects and fragility of epidermolysis bullosa simplex with cardiomyopathy.
    Logli E; Marzuolo E; D'Agostino M; Conti LA; Lena AM; Diociaiuti A; Dellambra E; Has C; Cianfanelli V; Zambruno G; El Hachem M; Magenta A; Candi E; Condorelli AG
    Hum Mol Genet; 2022 Apr; 31(8):1308-1324. PubMed ID: 34740256
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Generation and characterization of epidermolysis bullosa simplex cell lines: scratch assays show faster migration with disruptive keratin mutations.
    Morley SM; D'Alessandro M; Sexton C; Rugg EL; Navsaria H; Shemanko CS; Huber M; Hohl D; Heagerty AI; Leigh IM; Lane EB
    Br J Dermatol; 2003 Jul; 149(1):46-58. PubMed ID: 12890194
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Drosophila Model of Epidermolysis Bullosa Simplex.
    Bohnekamp J; Cryderman DE; Paululat A; Baccam GC; Wallrath LL; Magin TM
    J Invest Dermatol; 2015 Aug; 135(8):2031-2039. PubMed ID: 25830653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel and recurrent mutations in keratin KRT5 and KRT14 genes in epidermolysis bullosa simplex: implications for disease phenotype and keratin filament assembly.
    Müller FB; Küster W; Wodecki K; Almeida H; Bruckner-Tuderman L; Krieg T; Korge BP; Arin MJ
    Hum Mutat; 2006 Jul; 27(7):719-20. PubMed ID: 16786515
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein.
    Chan Y; Anton-Lamprecht I; Yu QC; Jäckel A; Zabel B; Ernst JP; Fuchs E
    Genes Dev; 1994 Nov; 8(21):2574-87. PubMed ID: 7525408
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Co-chaperone CHIP associates with mutant Cu/Zn-superoxide dismutase proteins linked to familial amyotrophic lateral sclerosis and promotes their degradation by proteasomes.
    Choi JS; Cho S; Park SG; Park BC; Lee DH
    Biochem Biophys Res Commun; 2004 Aug; 321(3):574-83. PubMed ID: 15358145
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A cell-based drug discovery assay identifies inhibition of cell stress responses as a new approach to treatment of epidermolysis bullosa simplex.
    Tan TS; Common JEA; Lim JSY; Badowski C; Firdaus MJ; Leonardi SS; Lane EB
    J Cell Sci; 2021 Oct; 134(19):. PubMed ID: 34643242
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase.
    Xia T; Dimitropoulou C; Zeng J; Antonova GN; Snead C; Venema RC; Fulton D; Qian S; Patterson C; Papapetropoulos A; Catravas JD
    Am J Physiol Heart Circ Physiol; 2007 Nov; 293(5):H3080-7. PubMed ID: 17873020
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Keratin mutations in patients with epidermolysis bullosa simplex: correlations between phenotype severity and disturbance of intermediate filament molecular structure.
    Jerábková B; Marek J; Bucková H; Kopecková L; Veselý K; Valícková J; Fajkus J; Fajkusová L
    Br J Dermatol; 2010 May; 162(5):1004-13. PubMed ID: 20030639
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination.
    Hirayama S; Yamazaki Y; Kitamura A; Oda Y; Morito D; Okawa K; Kimura H; Cyr DM; Kubota H; Nagata K
    Mol Biol Cell; 2008 Mar; 19(3):899-911. PubMed ID: 18094050
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling.
    Demand J; Alberti S; Patterson C; Höhfeld J
    Curr Biol; 2001 Oct; 11(20):1569-77. PubMed ID: 11676916
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha.
    Fan M; Park A; Nephew KP
    Mol Endocrinol; 2005 Dec; 19(12):2901-14. PubMed ID: 16037132
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Purification and assay of the chaperone-dependent ubiquitin ligase of the carboxyl terminus of Hsc70-interacting protein.
    Murata S; Minami M; Minami Y
    Methods Enzymol; 2005; 398():271-9. PubMed ID: 16275335
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Defining the properties of the nonhelical tail domain in type II keratin 5: insight from a bullous disease-causing mutation.
    Gu LH; Coulombe PA
    Mol Biol Cell; 2005 Mar; 16(3):1427-38. PubMed ID: 15647384
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hsp40 regulates the amount of keratin proteins via ubiquitin-proteasome pathway in cultured human cells.
    Yamazaki S; Uchiumi A; Katagata Y
    Int J Mol Med; 2012 Feb; 29(2):165-8. PubMed ID: 22075554
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.