BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 20153822)

  • 41. Human mitochondrial DNA polymerase holoenzyme: reconstitution and characterization.
    Johnson AA; Tsai Yc; Graves SW; Johnson KA
    Biochemistry; 2000 Feb; 39(7):1702-8. PubMed ID: 10677218
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Increased dNTP pools rescue mtDNA depletion in human POLG-deficient fibroblasts.
    Blázquez-Bermejo C; Carreño-Gago L; Molina-Granada D; Aguirre J; Ramón J; Torres-Torronteras J; Cabrera-Pérez R; Martín MÁ; Domínguez-González C; de la Cruz X; Lombès A; García-Arumí E; Martí R; Cámara Y
    FASEB J; 2019 Jun; 33(6):7168-7179. PubMed ID: 30848931
    [TBL] [Abstract][Full Text] [Related]  

  • 43. POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity.
    Young MJ; Humble MM; DeBalsi KL; Sun KY; Copeland WC
    Hum Mol Genet; 2015 Sep; 24(18):5184-97. PubMed ID: 26123486
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa.
    Sassa A; Niimi N; Fujimoto H; Katafuchi A; Grúz P; Yasui M; Gupta RC; Johnson F; Ohta T; Nohmi T
    Mutat Res; 2011 Jan; 718(1-2):10-7. PubMed ID: 21078407
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Distal myopathy with cachexia: an unrecognised phenotype caused by dominantly-inherited mitochondrial polymerase γ mutations.
    Pitceathly RD; Tomlinson SE; Hargreaves I; Bhardwaj N; Holton JL; Morrow JM; Evans J; Smith C; Fratter C; Woodward CE; Sweeney MG; Rahman S; Hanna MG
    J Neurol Neurosurg Psychiatry; 2013 Jan; 84(1):107-10. PubMed ID: 22933815
    [TBL] [Abstract][Full Text] [Related]  

  • 46. POLG exon 22 skipping induced by different mechanisms in two unrelated cases of Alpers syndrome.
    Mousson de Camaret B; Chassagne M; Mayençon M; Padet S; Crehalet H; Clerc-Renaud P; Rouvet I; Zabot MT; Rivier F; Sarda P; des Portes V; Bozon D
    Mitochondrion; 2011 Jan; 11(1):223-7. PubMed ID: 20691285
    [TBL] [Abstract][Full Text] [Related]  

  • 47. A single mutation in human mitochondrial DNA polymerase Pol gammaA affects both polymerization and proofreading activities of only the holoenzyme.
    Lee YS; Johnson KA; Molineux IJ; Yin YW
    J Biol Chem; 2010 Sep; 285(36):28105-16. PubMed ID: 20513922
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Zebrafish lacking functional DNA polymerase gamma survive to juvenile stage, despite rapid and sustained mitochondrial DNA depletion, altered energetics and growth.
    Rahn JJ; Bestman JE; Stackley KD; Chan SS
    Nucleic Acids Res; 2015 Dec; 43(21):10338-52. PubMed ID: 26519465
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Consequences of the pathogenic T9176C mutation of human mitochondrial DNA on yeast mitochondrial ATP synthase.
    Kucharczyk R; Ezkurdia N; Couplan E; Procaccio V; Ackerman SH; Blondel M; di Rago JP
    Biochim Biophys Acta; 2010; 1797(6-7):1105-12. PubMed ID: 20056103
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis.
    Randell JC; Komazin G; Jiang C; Hwang CB; Coen DM
    J Virol; 2005 Sep; 79(18):12025-34. PubMed ID: 16140778
    [TBL] [Abstract][Full Text] [Related]  

  • 51. POLG mutations causing ophthalmoplegia, sensorimotor polyneuropathy, ataxia, and deafness.
    Mancuso M; Filosto M; Bellan M; Liguori R; Montagna P; Baruzzi A; DiMauro S; Carelli V
    Neurology; 2004 Jan; 62(2):316-8. PubMed ID: 14745080
    [TBL] [Abstract][Full Text] [Related]  

  • 52. DNA polymerase gamma, the mitochondrial replicase.
    Kaguni LS
    Annu Rev Biochem; 2004; 73():293-320. PubMed ID: 15189144
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Yeast model analysis of novel polymerase gamma variants found in patients with autosomal recessive mitochondrial disease.
    Kaliszewska M; Kruszewski J; Kierdaszuk B; Kostera-Pruszczyk A; Nojszewska M; Łusakowska A; Vizueta J; Sabat D; Lutyk D; Lower M; Piekutowska-Abramczuk D; Kaniak-Golik A; Pronicka E; Kamińska A; Bartnik E; Golik P; Tońska K
    Hum Genet; 2015 Sep; 134(9):951-66. PubMed ID: 26077851
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Patient homozygous for a recessive POLG mutation presents with features of MERRF.
    Van Goethem G; Mercelis R; Löfgren A; Seneca S; Ceuterick C; Martin JJ; Van Broeckhoven C
    Neurology; 2003 Dec; 61(12):1811-3. PubMed ID: 14694057
    [TBL] [Abstract][Full Text] [Related]  

  • 55. The A467T and W748S POLG substitutions are a rare cause of adult-onset ataxia in Europe.
    Craig K; Ferrari G; Tiangyou W; Hudson G; Gellera C; Zeviani M; Chinnery PF
    Brain; 2007 Apr; 130(Pt 4):E69; author reply E70. PubMed ID: 17438011
    [No Abstract]   [Full Text] [Related]  

  • 56. Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity.
    Longley MJ; Ropp PA; Lim SE; Copeland WC
    Biochemistry; 1998 Jul; 37(29):10529-39. PubMed ID: 9671525
    [TBL] [Abstract][Full Text] [Related]  

  • 57. The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit.
    Longley MJ; Nguyen D; Kunkel TA; Copeland WC
    J Biol Chem; 2001 Oct; 276(42):38555-62. PubMed ID: 11504725
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis.
    Ponamarev MV; Longley MJ; Nguyen D; Kunkel TA; Copeland WC
    J Biol Chem; 2002 May; 277(18):15225-8. PubMed ID: 11897778
    [TBL] [Abstract][Full Text] [Related]  

  • 59. phi29 DNA polymerase active site: role of residue Val250 as metal-dNTP complex ligand and in protein-primed initiation.
    Pérez-Arnaiz P; Lázaro JM; Salas M; de Vega M
    J Mol Biol; 2010 Jan; 395(2):223-33. PubMed ID: 19883660
    [TBL] [Abstract][Full Text] [Related]  

  • 60. POLG mutations in Alpers syndrome.
    Nguyen KV; Østergaard E; Ravn SH; Balslev T; Danielsen ER; Vardag A; McKiernan PJ; Gray G; Naviaux RK
    Neurology; 2005 Nov; 65(9):1493-5. PubMed ID: 16177225
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.