302 related articles for article (PubMed ID: 20154090)
1. Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS).
Hanson KA; Kim SH; Wassarman DA; Tibbetts RS
J Biol Chem; 2010 Apr; 285(15):11068-72. PubMed ID: 20154090
[TBL] [Abstract][Full Text] [Related]
2. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.
Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC
Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911
[TBL] [Abstract][Full Text] [Related]
3. Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1.
Kim SH; Shi Y; Hanson KA; Williams LM; Sakasai R; Bowler MJ; Tibbetts RS
J Biol Chem; 2009 Mar; 284(12):8083-92. PubMed ID: 19112176
[TBL] [Abstract][Full Text] [Related]
4. Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis.
Tashiro Y; Urushitani M; Inoue H; Koike M; Uchiyama Y; Komatsu M; Tanaka K; Yamazaki M; Abe M; Misawa H; Sakimura K; Ito H; Takahashi R
J Biol Chem; 2012 Dec; 287(51):42984-94. PubMed ID: 23095749
[TBL] [Abstract][Full Text] [Related]
5. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
Xiao S; Sanelli T; Chiang H; Sun Y; Chakrabartty A; Keith J; Rogaeva E; Zinman L; Robertson J
Acta Neuropathol; 2015 Jul; 130(1):49-61. PubMed ID: 25788357
[TBL] [Abstract][Full Text] [Related]
6. Neuronal function and dysfunction of Drosophila dTDP.
Lin MJ; Cheng CW; Shen CK
PLoS One; 2011; 6(6):e20371. PubMed ID: 21673800
[TBL] [Abstract][Full Text] [Related]
7. Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS.
Chang JC; Hazelett DJ; Stewart JA; Morton DB
Brain Res; 2014 Oct; 1584():39-51. PubMed ID: 24275199
[TBL] [Abstract][Full Text] [Related]
8. The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis.
Chen HJ; Mitchell JC; Novoselov S; Miller J; Nishimura AL; Scotter EL; Vance CA; Cheetham ME; Shaw CE
Brain; 2016 May; 139(Pt 5):1417-32. PubMed ID: 26936937
[TBL] [Abstract][Full Text] [Related]
9. Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies.
Miguel L; Frébourg T; Campion D; Lecourtois M
Neurobiol Dis; 2011 Feb; 41(2):398-406. PubMed ID: 20951205
[TBL] [Abstract][Full Text] [Related]
10. Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.
Matsukawa K; Hashimoto T; Matsumoto T; Ihara R; Chihara T; Miura M; Wakabayashi T; Iwatsubo T
J Biol Chem; 2016 Nov; 291(45):23464-23476. PubMed ID: 27634045
[TBL] [Abstract][Full Text] [Related]
11. PABPN1 suppresses TDP-43 toxicity in ALS disease models.
Chou CC; Alexeeva OM; Yamada S; Pribadi A; Zhang Y; Mo B; Williams KR; Zarnescu DC; Rossoll W
Hum Mol Genet; 2015 Sep; 24(18):5154-73. PubMed ID: 26130692
[TBL] [Abstract][Full Text] [Related]
12. Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Riku Y; Watanabe H; Yoshida M; Tatsumi S; Mimuro M; Iwasaki Y; Katsuno M; Iguchi Y; Masuda M; Senda J; Ishigaki S; Udagawa T; Sobue G
JAMA Neurol; 2014 Feb; 71(2):172-9. PubMed ID: 24378564
[TBL] [Abstract][Full Text] [Related]
13. Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS.
Estes PS; Boehringer A; Zwick R; Tang JE; Grigsby B; Zarnescu DC
Hum Mol Genet; 2011 Jun; 20(12):2308-21. PubMed ID: 21441568
[TBL] [Abstract][Full Text] [Related]
14. Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.
Cheng CW; Lin MJ; Shen CK
J Neurogenet; 2015; 29(2-3):59-68. PubMed ID: 26219309
[TBL] [Abstract][Full Text] [Related]
15. The Overexpression of TDP-43 Protein in the Neuron and Oligodendrocyte Cells Causes the Progressive Motor Neuron Degeneration in the SOD1 G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.
Lu Y; Tang C; Zhu L; Li J; Liang H; Zhang J; Xu R
Int J Biol Sci; 2016; 12(9):1140-9. PubMed ID: 27570488
[TBL] [Abstract][Full Text] [Related]
16. RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
Ihara R; Matsukawa K; Nagata Y; Kunugi H; Tsuji S; Chihara T; Kuranaga E; Miura M; Wakabayashi T; Hashimoto T; Iwatsubo T
Hum Mol Genet; 2013 Nov; 22(22):4474-84. PubMed ID: 23804749
[TBL] [Abstract][Full Text] [Related]
17. Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD.
Diaper DC; Adachi Y; Lazarou L; Greenstein M; Simoes FA; Di Domenico A; Solomon DA; Lowe S; Alsubaie R; Cheng D; Buckley S; Humphrey DM; Shaw CE; Hirth F
Hum Mol Genet; 2013 Oct; 22(19):3883-93. PubMed ID: 23727833
[TBL] [Abstract][Full Text] [Related]
18. A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects.
Langellotti S; Romano V; Romano G; Klima R; Feiguin F; Cragnaz L; Romano M; Baralle FE
Dis Model Mech; 2016 Jun; 9(6):659-69. PubMed ID: 27101846
[TBL] [Abstract][Full Text] [Related]
19. Neuronal Expression of UBQLN2
Picher-Martel V; Renaud L; Bareil C; Julien JP
Mol Neurobiol; 2019 Jul; 56(7):4680-4696. PubMed ID: 30377984
[TBL] [Abstract][Full Text] [Related]
20. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]