269 related articles for article (PubMed ID: 20154219)
1. CLEC-2 activates Syk through dimerization.
Hughes CE; Pollitt AY; Mori J; Eble JA; Tomlinson MG; Hartwig JH; O'Callaghan CA; Fütterer K; Watson SP
Blood; 2010 Apr; 115(14):2947-55. PubMed ID: 20154219
[TBL] [Abstract][Full Text] [Related]
2. The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade.
Fuller GL; Williams JA; Tomlinson MG; Eble JA; Hanna SL; Pöhlmann S; Suzuki-Inoue K; Ozaki Y; Watson SP; Pearce AC
J Biol Chem; 2007 Apr; 282(17):12397-409. PubMed ID: 17339324
[TBL] [Abstract][Full Text] [Related]
3. G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2.
Mori J; Pearce AC; Spalton JC; Grygielska B; Eble JA; Tomlinson MG; Senis YA; Watson SP
J Biol Chem; 2008 Dec; 283(51):35419-27. PubMed ID: 18955485
[TBL] [Abstract][Full Text] [Related]
4. Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.
Manne BK; Badolia R; Dangelmaier C; Eble JA; Ellmeier W; Kahn M; Kunapuli SP
J Biol Chem; 2015 May; 290(18):11557-68. PubMed ID: 25767114
[TBL] [Abstract][Full Text] [Related]
5. Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling.
Séverin S; Pollitt AY; Navarro-Nuñez L; Nash CA; Mourão-Sá D; Eble JA; Senis YA; Watson SP
J Biol Chem; 2011 Feb; 286(6):4107-16. PubMed ID: 21098033
[TBL] [Abstract][Full Text] [Related]
6. Critical Role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type lectin receptor-2).
Hughes CE; Sinha U; Pandey A; Eble JA; O'Callaghan CA; Watson SP
J Biol Chem; 2013 Feb; 288(7):5127-35. PubMed ID: 23264619
[TBL] [Abstract][Full Text] [Related]
7. A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.
Suzuki-Inoue K; Fuller GL; García A; Eble JA; Pöhlmann S; Inoue O; Gartner TK; Hughan SC; Pearce AC; Laing GD; Theakston RD; Schweighoffer E; Zitzmann N; Morita T; Tybulewicz VL; Ozaki Y; Watson SP
Blood; 2006 Jan; 107(2):542-9. PubMed ID: 16174766
[TBL] [Abstract][Full Text] [Related]
8. The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signaling in platelets.
Spalton JC; Mori J; Pollitt AY; Hughes CE; Eble JA; Watson SP
J Thromb Haemost; 2009 Jul; 7(7):1192-9. PubMed ID: 19422460
[TBL] [Abstract][Full Text] [Related]
9. Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia.
Hardy AT; Palma-Barqueros V; Watson SK; Malcor JD; Eble JA; Gardiner EE; Blanco JE; Guijarro-Campillo R; Delgado JL; Lozano ML; Teruel-Montoya R; Vicente V; Watson SP; Rivera J; Ferrer-Marín F
Thromb Haemost; 2018 Jun; 118(6):1009-1020. PubMed ID: 29695020
[TBL] [Abstract][Full Text] [Related]
10. Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling.
Navarro-Núñez L; Pollitt AY; Lowe K; Latif A; Nash GB; Watson SP
Thromb Haemost; 2015 May; 113(5):1109-20. PubMed ID: 25694214
[TBL] [Abstract][Full Text] [Related]
11. Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac.
Pollitt AY; Grygielska B; Leblond B; Désiré L; Eble JA; Watson SP
Blood; 2010 Apr; 115(14):2938-46. PubMed ID: 20154214
[TBL] [Abstract][Full Text] [Related]
12. The N-terminal SH2 domain of Syk is required for (hem)ITAM, but not integrin, signaling in mouse platelets.
Hughes CE; Finney BA; Koentgen F; Lowe KL; Watson SP
Blood; 2015 Jan; 125(1):144-54. PubMed ID: 25352128
[TBL] [Abstract][Full Text] [Related]
13. C-type lectin-like receptor-2 (CLEC-2) is a key regulator of kappa-carrageenan-induced tail thrombosis model in mice.
Yokomori R; Shirai T; Tsukiji N; Oishi S; Sasaki T; Takano K; Suzuki-Inoue K
Platelets; 2023 Dec; 34(1):2281941. PubMed ID: 38010137
[TBL] [Abstract][Full Text] [Related]
14. Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β.
Moroi AJ; Watson SP
J Thromb Haemost; 2015 Jun; 13(6):1139-50. PubMed ID: 25858425
[TBL] [Abstract][Full Text] [Related]
15. Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization.
Lorenz V; Stegner D; Stritt S; Vögtle T; Kiefer F; Witke W; Schymeinsky J; Watson SP; Walzog B; Nieswandt B
Blood; 2015 Jun; 125(26):4069-77. PubMed ID: 25795918
[TBL] [Abstract][Full Text] [Related]
16. G
Badolia R; Inamdar V; Manne BK; Dangelmaier C; Eble JA; Kunapuli SP
J Biol Chem; 2017 Sep; 292(35):14516-14531. PubMed ID: 28705934
[TBL] [Abstract][Full Text] [Related]
17. Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.
Pollitt AY; Poulter NS; Gitz E; Navarro-Nuñez L; Wang YJ; Hughes CE; Thomas SG; Nieswandt B; Douglas MR; Owen DM; Jackson DG; Dustin ML; Watson SP
J Biol Chem; 2014 Dec; 289(52):35695-710. PubMed ID: 25368330
[TBL] [Abstract][Full Text] [Related]
18. Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor.
Yanaga F; Poole A; Asselin J; Blake R; Schieven GL; Clark EA; Law CL; Watson SP
Biochem J; 1995 Oct; 311 ( Pt 2)(Pt 2):471-8. PubMed ID: 7487883
[TBL] [Abstract][Full Text] [Related]
19. Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms.
Buitrago L; Bhavanasi D; Dangelmaier C; Manne BK; Badolia R; Borgognone A; Tsygankov AY; McKenzie SE; Kunapuli SP
J Biol Chem; 2013 Oct; 288(40):29160-9. PubMed ID: 23960082
[TBL] [Abstract][Full Text] [Related]
20. Control of Platelet CLEC-2-Mediated Activation by Receptor Clustering and Tyrosine Kinase Signaling.
Martyanov AA; Balabin FA; Dunster JL; Panteleev MA; Gibbins JM; Sveshnikova AN
Biophys J; 2020 Jun; 118(11):2641-2655. PubMed ID: 32396849
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
