BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

92 related articles for article (PubMed ID: 2015591)

  • 1. Construction of a human shuttle vector containing a single nitrogen mustard interstrand, DNA-DNA cross-link at a unique plasmid location.
    Grueneberg DA; Ojwang JO; Benasutti M; Hartman S; Loechler EL
    Cancer Res; 1991 May; 51(9):2268-72. PubMed ID: 2015591
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of a duplex oligonucleotide containing a nitrogen mustard interstrand DNA-DNA cross-link.
    Ojwang JO; Grueneberg DA; Loechler EL
    Cancer Res; 1989 Dec; 49(23):6529-37. PubMed ID: 2819709
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
    McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
    Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and structural characterization of the N2G-mitomycin C-N2G interstrand cross-link in a model synthetic 23 base pair oligonucleotide DNA duplex.
    Warren AJ; Hamilton JW
    Chem Res Toxicol; 1996; 9(7):1063-71. PubMed ID: 8902260
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards.
    Balcome S; Park S; Quirk Dorr DR; Hafner L; Phillips L; Tretyakova N
    Chem Res Toxicol; 2004 Jul; 17(7):950-62. PubMed ID: 15257621
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of DNA sequence and minor groove selective alkylating agents.
    Lee M; Rhodes AL; Wyatt MD; Forrow S; Hartley JA
    Anticancer Drug Des; 1993 Jun; 8(3):173-92. PubMed ID: 8517912
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence-selective interaction of the minor-groove interstrand cross-linking agent SJG-136 with naked and cellular DNA: footprinting and enzyme inhibition studies.
    Martin C; Ellis T; McGurk CJ; Jenkins TC; Hartley JA; Waring MJ; Thurston DE
    Biochemistry; 2005 Mar; 44(11):4135-47. PubMed ID: 15766241
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A New Cross-Link for an Old Cross-Linking Drug: The Nitrogen Mustard Anticancer Agent Mechlorethamine Generates Cross-Links Derived from Abasic Sites in Addition to the Expected Drug-Bridged Cross-Links.
    Nejad MI; Johnson KM; Price NE; Gates KS
    Biochemistry; 2016 Dec; 55(50):7033-7041. PubMed ID: 27992994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex.
    Berners-Price SJ; Davies MS; Cox JW; Thomas DS; Farrell N
    Chemistry; 2003 Feb; 9(3):713-25. PubMed ID: 12569464
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flanking sequences modulate diepoxide and mustard cross-linking efficiencies at the 5'-GNC site.
    Sawyer GA; Frederick ED; Millard JT
    Chem Res Toxicol; 2004 Aug; 17(8):1057-63. PubMed ID: 15310237
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure, flexibility, and repair of two different orientations of the same alkyl interstrand DNA cross-link.
    Noll DM; Webba da Silva M; Noronha AM; Wilds CJ; Colvin OM; Gamcsik MP; Miller PS
    Biochemistry; 2005 May; 44(18):6764-75. PubMed ID: 15865422
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and characterization of DNA containing an N1-2'-deoxyinosine-ethyl-N3-thymidine interstrand cross-link: a structural mimic of the cross-link formed by 1,3-bis-(2-chloroethyl)-1-nitrosourea.
    Wilds CJ; Xu F; Noronha AM
    Chem Res Toxicol; 2008 Mar; 21(3):686-95. PubMed ID: 18257558
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links.
    Rahman KM; Thompson AS; James CH; Narayanaswamy M; Thurston DE
    J Am Chem Soc; 2009 Sep; 131(38):13756-66. PubMed ID: 19725510
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of nucleosome structure on DNA interstrand cross-linking reactions.
    Millard JT; Spencer RJ; Hopkins PB
    Biochemistry; 1998 Apr; 37(15):5211-9. PubMed ID: 9548752
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Highly efficient sequence-specific DNA interstrand cross-linking by pyrrole/imidazole CPI conjugates.
    Bando T; Narita A; Saito I; Sugiyama H
    J Am Chem Soc; 2003 Mar; 125(12):3471-85. PubMed ID: 12643709
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anomalous cross-linking by mechlorethamine of DNA duplexes containing C-C mismatch pairs.
    Romero RM; Mitas M; Haworth IS
    Biochemistry; 1999 Mar; 38(12):3641-8. PubMed ID: 10090751
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Recognition of DNA interstrand cross-link of antitumor cisplatin by HMGB1 protein.
    Kasparkova J; Delalande O; Stros M; Elizondo-Riojas MA; Vojtiskova M; Kozelka J; Brabec V
    Biochemistry; 2003 Feb; 42(5):1234-44. PubMed ID: 12564926
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene-specific DNA interstrand cross-links produced by nitrogen mustard in the human tumor cell line Colo320HSR.
    Futscher BW; Pieper RO; Dalton WS; Erickson LC
    Cell Growth Differ; 1992 Apr; 3(4):217-23. PubMed ID: 1515367
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interstrand cross-link induction by UV radiation in bromodeoxyuridine-substituted DNA: dependence on DNA conformation.
    Cecchini S; Masson C; La Madeleine C; Huels MA; Sanche L; Wagner JR; Hunting DJ
    Biochemistry; 2005 Dec; 44(51):16957-66. PubMed ID: 16363809
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure elucidation of DNA interstrand cross-link by a combination of nuclease P1 digestion with mass spectrometry.
    Wang Y; Wang Y
    Anal Chem; 2003 Nov; 75(22):6306-13. PubMed ID: 14616015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.