205 related articles for article (PubMed ID: 20157915)
21. Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental compounds.
Kudo M; Ohi M; Aoyama Y; Nitahara Y; Chung SK; Yoshida Y
J Biochem; 2005 May; 137(5):625-32. PubMed ID: 15944416
[TBL] [Abstract][Full Text] [Related]
22. Homology model, molecular dynamics simulation and novel pyrazole analogs design of Candida albicans CYP450 lanosterol 14 α-demethylase, a target enzyme for antifungal therapy.
Jacob K S; Ganguly S; Kumar P; Poddar R; Kumar A
J Biomol Struct Dyn; 2017 May; 35(7):1446-1463. PubMed ID: 27142238
[TBL] [Abstract][Full Text] [Related]
23. Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents.
Lamb DC; Kelly DE; Waterman MR; Stromstedt M; Rozman D; Kelly SL
Yeast; 1999 Jun; 15(9):755-63. PubMed ID: 10398344
[TBL] [Abstract][Full Text] [Related]
24. Modeling and interactions of Aspergillus fumigatus lanosterol 14-alpha demethylase 'A' with azole antifungals.
Gollapudy R; Ajmani S; Kulkarni SA
Bioorg Med Chem; 2004 Jun; 12(11):2937-50. PubMed ID: 15142553
[TBL] [Abstract][Full Text] [Related]
25. Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.
Xiao L; Madison V; Chau AS; Loebenberg D; Palermo RE; McNicholas PM
Antimicrob Agents Chemother; 2004 Feb; 48(2):568-74. PubMed ID: 14742211
[TBL] [Abstract][Full Text] [Related]
26. The Evolution of Azole Resistance in
Warrilow AG; Nishimoto AT; Parker JE; Price CL; Flowers SA; Kelly DE; Rogers PD; Kelly SL
Antimicrob Agents Chemother; 2019 May; 63(5):. PubMed ID: 30783005
[TBL] [Abstract][Full Text] [Related]
27. Antifungal screening and in silico mechanistic studies of an in-house azole library.
Sari S; Kart D; Sabuncuoğlu S; Doğan İS; Özdemir Z; Bozbey İ; Gencel M; Eşsiz Ş; Reynisson J; Karakurt A; Saraç S; Dalkara S
Chem Biol Drug Des; 2019 Sep; 94(5):1944-1955. PubMed ID: 31260179
[TBL] [Abstract][Full Text] [Related]
28. Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking.
Sheng C; Zhang W; Ji H; Zhang M; Song Y; Xu H; Zhu J; Miao Z; Jiang Q; Yao J; Zhou Y; Zhu J; Lü J
J Med Chem; 2006 Apr; 49(8):2512-25. PubMed ID: 16610794
[TBL] [Abstract][Full Text] [Related]
29. Design, synthesis and antifungal evaluation of 1-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)-1H-1,2,4-triazol-5(4H)-one.
Jiang Y; Cao Y; Zhang J; Zou Y; Chai X; Hu H; Zhao Q; Wu Q; Zhang D; Jiang Y; Sun Q
Eur J Med Chem; 2011 Jul; 46(7):3135-41. PubMed ID: 21354675
[TBL] [Abstract][Full Text] [Related]
30. Differential inhibition of human CYP3A4 and Candida albicans CYP51 with azole antifungal agents.
Lamb DC; Kelly DE; Baldwin BC; Kelly SL
Chem Biol Interact; 2000 Mar; 125(3):165-75. PubMed ID: 10731517
[TBL] [Abstract][Full Text] [Related]
31. Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals.
Tyndall JD; Sabherwal M; Sagatova AA; Keniya MV; Negroni J; Wilson RK; Woods MA; Tietjen K; Monk BC
PLoS One; 2016; 11(12):e0167485. PubMed ID: 27907120
[TBL] [Abstract][Full Text] [Related]
32. Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions.
Sheng C; Zhang W; Zhang M; Song Y; Ji H; Zhu J; Yao J; Yu J; Yang S; Zhou Y; Zhu J; Lu J
J Biomol Struct Dyn; 2004 Aug; 22(1):91-9. PubMed ID: 15214809
[TBL] [Abstract][Full Text] [Related]
33. Small-Molecule Inhibitors Targeting Sterol 14α-Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans.
Binjubair FA; Parker JE; Warrilow AG; Puri K; Braidley PJ; Tatar E; Kelly SL; Kelly DE; Simons C
ChemMedChem; 2020 Jul; 15(14):1294-1309. PubMed ID: 32459374
[TBL] [Abstract][Full Text] [Related]
34. Molecular Modeling Studies of Halogenated Imidazoles against 14α- Demethylase from Candida Albicans for Treating Fungal Infections.
Rani N; Kumar P; Singh R
Infect Disord Drug Targets; 2020; 20(2):208-222. PubMed ID: 30499421
[TBL] [Abstract][Full Text] [Related]
35. New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis.
Campos Péret VA; Reis RCFM; Braga SFP; Benedetti MD; Caldas IS; Carvalho DT; Santana LFA; Johann S; Souza TB
Eur J Med Chem; 2023 Aug; 256():115436. PubMed ID: 37146343
[TBL] [Abstract][Full Text] [Related]
36. Novel antifungal agents which inhibit lanosterol 14alpha-demethylase in Candida albicans CCH442.
Zakula D; Capobianco JO; Goldman RC
J Antimicrob Chemother; 1997 Feb; 39(2):261-4. PubMed ID: 9069550
[TBL] [Abstract][Full Text] [Related]
37. Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase.
Sagatova AA; Keniya MV; Wilson RK; Monk BC; Tyndall JD
Antimicrob Agents Chemother; 2015 Aug; 59(8):4982-9. PubMed ID: 26055382
[TBL] [Abstract][Full Text] [Related]
38. Design, synthesis and molecular docking studies of novel triazole as antifungal agent.
Chai X; Zhang J; Cao Y; Zou Y; Wu Q; Zhang D; Jiang Y; Sun Q
Eur J Med Chem; 2011 Jul; 46(7):3167-76. PubMed ID: 21531485
[TBL] [Abstract][Full Text] [Related]
39. Design, synthesis and evaluation of benzoheterocycle analogues as potent antifungal agents targeting CYP51.
Zhao S; Wei P; Wu M; Zhang X; Zhao L; Jiang X; Hao C; Su X; Zhao D; Cheng M
Bioorg Med Chem; 2018 Jul; 26(12):3242-3253. PubMed ID: 29748145
[TBL] [Abstract][Full Text] [Related]
40. Imidazolylchromanones containing non-benzylic oxime ethers: synthesis and molecular modeling study of new azole antifungals selective against Cryptococcus gattii.
Babazadeh-Qazijahani M; Badali H; Irannejad H; Afsarian MH; Emami S
Eur J Med Chem; 2014 Apr; 76():264-73. PubMed ID: 24583607
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
