BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

612 related articles for article (PubMed ID: 20160076)

  • 1. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
    Alexander A; Cai SL; Kim J; Nanez A; Sahin M; MacLean KH; Inoki K; Guan KL; Shen J; Person MD; Kusewitt D; Mills GB; Kastan MB; Walker CL
    Proc Natl Acad Sci U S A; 2010 Mar; 107(9):4153-8. PubMed ID: 20160076
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
    Tripathi DN; Chowdhury R; Trudel LJ; Tee AR; Slack RS; Walker CL; Wogan GN
    Proc Natl Acad Sci U S A; 2013 Aug; 110(32):E2950-7. PubMed ID: 23878245
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATM engages the TSC2/mTORC1 signaling node to regulate autophagy.
    Alexander A; Kim J; Walker CL
    Autophagy; 2010 Jul; 6(5):672-3. PubMed ID: 20581436
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential localization of ATM is correlated with activation of distinct downstream signaling pathways.
    Alexander A; Walker CL
    Cell Cycle; 2010 Sep; 9(18):3685-6. PubMed ID: 20890104
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.
    Cam H; Easton JB; High A; Houghton PJ
    Mol Cell; 2010 Nov; 40(4):509-20. PubMed ID: 21095582
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATM localization and gene expression in the adult mouse eye.
    Leemput J; Masson C; Bigot K; Errachid A; Dansault A; Provost A; Gadin S; Aoufouchi S; Menasche M; Abitbol M
    Mol Vis; 2009; 15():393-416. PubMed ID: 19234633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells.
    Huang Y; Ratovitski EA
    Aging (Albany NY); 2010 Dec; 2(12):959-68. PubMed ID: 21191146
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.
    Zhan H; Suzuki T; Aizawa K; Miyagawa K; Nagai R
    J Biol Chem; 2010 Sep; 285(38):29662-70. PubMed ID: 20639198
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1.
    Hong YS; Hong SW; Kim SM; Jin DH; Shin JS; Yoon DH; Kim KP; Lee JL; Heo DS; Lee JS; Kim TW
    Int J Oncol; 2012 Jul; 41(1):76-82. PubMed ID: 22552540
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain.
    Kanu N; Penicud K; Hristova M; Wong B; Irvine E; Plattner F; Raivich G; Behrens A
    J Biol Chem; 2010 Dec; 285(49):38534-42. PubMed ID: 20889973
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
    Huang X; Wullschleger S; Shpiro N; McGuire VA; Sakamoto K; Woods YL; McBurnie W; Fleming S; Alessi DR
    Biochem J; 2008 Jun; 412(2):211-21. PubMed ID: 18387000
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
    Wolff NC; Vega-Rubin-de-Celis S; Xie XJ; Castrillon DH; Kabbani W; Brugarolas J
    Mol Cell Biol; 2011 May; 31(9):1870-84. PubMed ID: 21383064
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.
    D'Souza AD; Parish IA; McKay SE; Kaech SM; Shadel GS
    Am J Pathol; 2011 Jun; 178(6):2740-51. PubMed ID: 21641396
    [TBL] [Abstract][Full Text] [Related]  

  • 14. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.
    Xie J; Ponuwei GA; Moore CE; Willars GB; Tee AR; Herbert TP
    Cell Signal; 2011 Dec; 23(12):1927-35. PubMed ID: 21763421
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit.
    Palii SS; Cui Y; Innes CL; Paules RS
    Cell Cycle; 2013 Apr; 12(7):1105-18. PubMed ID: 23462183
    [TBL] [Abstract][Full Text] [Related]  

  • 16. All stressed out without ATM kinase.
    Perry JJ; Tainer JA
    Sci Signal; 2011 Apr; 4(167):pe18. PubMed ID: 21467296
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
    Parkhitko AA; Priolo C; Coloff JL; Yun J; Wu JJ; Mizumura K; Xu W; Malinowska IA; Yu J; Kwiatkowski DJ; Locasale JW; Asara JM; Choi AM; Finkel T; Henske EP
    Mol Cancer Res; 2014 Jan; 12(1):48-57. PubMed ID: 24296756
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
    Shaw RJ
    Acta Physiol (Oxf); 2009 May; 196(1):65-80. PubMed ID: 19245654
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of AMP-activated protein kinase in cerebella of Atm-/- mice is attributable to accumulation of reactive oxygen species.
    Kuang X; Yan M; Ajmo JM; Scofield VL; Stoica G; Wong PK
    Biochem Biophys Res Commun; 2012 Feb; 418(2):267-72. PubMed ID: 22260947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lycopene inhibits Helicobacter pylori-induced ATM/ATR-dependent DNA damage response in gastric epithelial AGS cells.
    Jang SH; Lim JW; Morio T; Kim H
    Free Radic Biol Med; 2012 Feb; 52(3):607-615. PubMed ID: 22178412
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.