192 related articles for article (PubMed ID: 20160131)
1. Human cytochrome p450c17: single step purification and phosphorylation of serine 258 by protein kinase a.
Wang YH; Tee MK; Miller WL
Endocrinology; 2010 Apr; 151(4):1677-84. PubMed ID: 20160131
[TBL] [Abstract][Full Text] [Related]
2. The regulation of 17,20 lyase activity.
Miller WL; Auchus RJ; Geller DH
Steroids; 1997 Jan; 62(1):133-42. PubMed ID: 9029728
[TBL] [Abstract][Full Text] [Related]
3. Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
Lin D; Black SM; Nagahama Y; Miller WL
Endocrinology; 1993 Jun; 132(6):2498-506. PubMed ID: 8504753
[TBL] [Abstract][Full Text] [Related]
4. Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17.
Pandey AV; Miller WL
J Biol Chem; 2005 Apr; 280(14):13265-71. PubMed ID: 15687493
[TBL] [Abstract][Full Text] [Related]
5. Pathways leading to phosphorylation of p450c17 and to the posttranslational regulation of androgen biosynthesis.
Tee MK; Dong Q; Miller WL
Endocrinology; 2008 May; 149(5):2667-77. PubMed ID: 18187541
[TBL] [Abstract][Full Text] [Related]
6. Phosphorylation of human cytochrome P450c17 by p38α selectively increases 17,20 lyase activity and androgen biosynthesis.
Tee MK; Miller WL
J Biol Chem; 2013 Aug; 288(33):23903-13. PubMed ID: 23836902
[TBL] [Abstract][Full Text] [Related]
7. Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome.
Zhang LH; Rodriguez H; Ohno S; Miller WL
Proc Natl Acad Sci U S A; 1995 Nov; 92(23):10619-23. PubMed ID: 7479852
[TBL] [Abstract][Full Text] [Related]
8. The post-translational regulation of 17,20 lyase activity.
Miller WL; Tee MK
Mol Cell Endocrinol; 2015 Jun; 408():99-106. PubMed ID: 25224484
[TBL] [Abstract][Full Text] [Related]
9. Impact of differential P450c17 phosphorylation by cAMP stimulation and by starvation conditions on enzyme activities and androgen production in NCI-H295R cells.
Kempná P; Hirsch A; Hofer G; Mullis PE; Flück CE
Endocrinology; 2010 Aug; 151(8):3686-96. PubMed ID: 20534731
[TBL] [Abstract][Full Text] [Related]
10. P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5.
Geller DH; Auchus RJ; Miller WL
Mol Endocrinol; 1999 Jan; 13(1):167-75. PubMed ID: 9892022
[TBL] [Abstract][Full Text] [Related]
11. Mutagenesis of putative serine-threonine phosphorylation sites proximal to Arg255 of human cytochrome P450c17 does not selectively promote its 17,20-lyase activity.
Souter I; Munir I; Mallick P; Weitsman SR; Geller DH; Magoffin DA
Fertil Steril; 2006 Apr; 85 Suppl 1():1290-9. PubMed ID: 16616104
[TBL] [Abstract][Full Text] [Related]
12. Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer.
Auchus RJ; Lee TC; Miller WL
J Biol Chem; 1998 Feb; 273(6):3158-65. PubMed ID: 9452426
[TBL] [Abstract][Full Text] [Related]
13. Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species.
Brock BJ; Waterman MR
Biochemistry; 1999 Feb; 38(5):1598-606. PubMed ID: 9931027
[TBL] [Abstract][Full Text] [Related]
14. Molecular modeling of human P450c17 (17alpha-hydroxylase/17,20-lyase): insights into reaction mechanisms and effects of mutations.
Auchus RJ; Miller WL
Mol Endocrinol; 1999 Jul; 13(7):1169-82. PubMed ID: 10406467
[TBL] [Abstract][Full Text] [Related]
15. Expression and purification of functional human 17 alpha-hydroxylase/17,20-lyase (P450c17) in Escherichia coli. Use of this system for study of a novel form of combined 17 alpha-hydroxylase/17,20-lyase deficiency.
Imai T; Globerman H; Gertner JM; Kagawa N; Waterman MR
J Biol Chem; 1993 Sep; 268(26):19681-9. PubMed ID: 8396144
[TBL] [Abstract][Full Text] [Related]
16. The molecular basis of isolated 17,20 lyase deficiency.
Miller WL; Geller DH; Auchus RJ
Endocr Res; 1998; 24(3-4):817-25. PubMed ID: 9888582
[TBL] [Abstract][Full Text] [Related]
17. Enzymatic activities of P450c17 stably expressed in fibroblasts from patients with the polycystic ovary syndrome.
Martens JW; Geller DH; Arlt W; Auchus RJ; Ossovskaya VS; Rodriguez H; Dunaif A; Miller WL
J Clin Endocrinol Metab; 2000 Nov; 85(11):4338-46. PubMed ID: 11095477
[TBL] [Abstract][Full Text] [Related]
18. Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
Beaudoin C; Lavallée B; Tremblay Y; Hum DW; Breton R; de Launoit Y; Bélanger A
DNA Cell Biol; 1998 Aug; 17(8):707-15. PubMed ID: 9726253
[TBL] [Abstract][Full Text] [Related]
19. Pitfalls in characterizing P450c17 mutations associated with isolated 17,20-lyase deficiency.
Gupta MK; Geller DH; Auchus RJ
J Clin Endocrinol Metab; 2001 Sep; 86(9):4416-23. PubMed ID: 11549685
[TBL] [Abstract][Full Text] [Related]
20. The orphan nuclear receptor steroidogenic factor-1 regulates the cyclic adenosine 3',5'-monophosphate-mediated transcriptional activation of rat cytochrome P450c17 (17 alpha-hydroxylase/c17-20 lyase).
Zhang P; Mellon SH
Mol Endocrinol; 1996 Feb; 10(2):147-58. PubMed ID: 8825555
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
