These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 20160459)

  • 21. Secretase inhibitors and modulators for Alzheimer's disease treatment.
    Tomita T
    Expert Rev Neurother; 2009 May; 9(5):661-79. PubMed ID: 19402777
    [TBL] [Abstract][Full Text] [Related]  

  • 22. PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.
    Shiraishi H; Sai X; Wang HQ; Maeda Y; Kurono Y; Nishimura M; Yanagisawa K; Komano H
    J Neurochem; 2004 Sep; 90(6):1402-13. PubMed ID: 15341524
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.
    Li YM; Xu M; Lai MT; Huang Q; Castro JL; DiMuzio-Mower J; Harrison T; Lellis C; Nadin A; Neduvelil JG; Register RB; Sardana MK; Shearman MS; Smith AL; Shi XP; Yin KC; Shafer JA; Gardell SJ
    Nature; 2000 Jun; 405(6787):689-94. PubMed ID: 10864326
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Decreased Abeta secretion by cells expressing familial Alzheimer's disease-linked mutant presenilin 1.
    Shimojo M; Sahara N; Murayama M; Ichinose H; Takashima A
    Neurosci Res; 2007 Mar; 57(3):446-53. PubMed ID: 17210196
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease.
    Ryu YS; Park SY; Jung MS; Yoon SH; Kwen MY; Lee SY; Choi SH; Radnaabazar C; Kim MK; Kim H; Kim K; Song WJ; Chung SH
    J Neurochem; 2010 Nov; 115(3):574-84. PubMed ID: 20456003
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Presenilin function and gamma-secretase activity.
    Brunkan AL; Goate AM
    J Neurochem; 2005 May; 93(4):769-92. PubMed ID: 15857382
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
    Kuzuya A; Uemura K; Kitagawa N; Aoyagi N; Kihara T; Ninomiya H; Ishiura S; Takahashi R; Shimohama S
    J Neurosci Res; 2007 Jan; 85(1):153-65. PubMed ID: 17075903
    [TBL] [Abstract][Full Text] [Related]  

  • 28. [Pathogenesis of Alzheimer's disease: implications from amyloid research front].
    Iwatsubo T
    Rinsho Shinkeigaku; 2004 Nov; 44(11):768-70. PubMed ID: 15651286
    [TBL] [Abstract][Full Text] [Related]  

  • 29. CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.
    Zhou S; Zhou H; Walian PJ; Jap BK
    Proc Natl Acad Sci U S A; 2005 May; 102(21):7499-504. PubMed ID: 15890777
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells.
    Ramalho RM; Borralho PM; Castro RE; Solá S; Steer CJ; Rodrigues CM
    J Neurochem; 2006 Sep; 98(5):1610-8. PubMed ID: 16923170
    [TBL] [Abstract][Full Text] [Related]  

  • 31. An alternative spliced mouse presenilin-2 mRNA encodes a novel gamma-secretase inhibitor.
    Suzuki Y; Ohta K; Itoh M; Sakoh-Sumitomo Y; Mitsuda T; Ueda M; Hayakawa-Yano Y; Li S; Hida Y; Inuzuka T; Jung YK; Nakagawa T
    FEBS Lett; 2009 May; 583(9):1403-8. PubMed ID: 19376115
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Comparison of presenilin 1 and presenilin 2 γ-secretase activities using a yeast reconstitution system.
    Yonemura Y; Futai E; Yagishita S; Suo S; Tomita T; Iwatsubo T; Ishiura S
    J Biol Chem; 2011 Dec; 286(52):44569-75. PubMed ID: 22074918
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Pen-2 and Presenilin are Sufficient to Catalyze Notch Processing.
    Hu C; Xu J; Zeng L; Li T; Cui MZ; Xu X
    J Alzheimers Dis; 2017; 56(4):1263-1269. PubMed ID: 28234257
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.
    Evin G; Canterford LD; Hoke DE; Sharples RA; Culvenor JG; Masters CL
    Biochemistry; 2005 Mar; 44(11):4332-41. PubMed ID: 15766262
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase.
    Eccles MK; Main N; Carlessi R; Armstrong AM; Sabale M; Roberts-Mok B; Tirnitz-Parker JEE; Agostino M; Groth D; Fraser PE; Verdile G
    FASEB J; 2024 Jan; 38(1):e23396. PubMed ID: 38156414
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
    Ryazantseva M; Skobeleva K; Glushankova L; Kaznacheyeva E
    J Neurochem; 2016 Mar; 136(5):1085-95. PubMed ID: 26678016
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Are γ-secretase and its associated Alzheimer's disease γ problems?
    Rodríguez-Manotas M; Amorín-Díaz M; Cabezas-Herrera J; Acedo-Martínez A; Llorca-Escuín I
    Med Hypotheses; 2012 Feb; 78(2):299-304. PubMed ID: 22133557
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dominant negative effect of the loss-of-function γ-secretase mutants on the wild-type enzyme through heterooligomerization.
    Zhou R; Yang G; Shi Y
    Proc Natl Acad Sci U S A; 2017 Nov; 114(48):12731-12736. PubMed ID: 29078389
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Huannao Yicong Formula () regulates γ-secretase activity through APH-1 and PEN-2 gene ragulation pathways in hippocampus of APP/PS1 double transgenic mice.
    Wang ZY; Liu JG; Wei Y; Liu MX; Wang Q; Liang L; Yang HM; Li H
    Chin J Integr Med; 2017 Apr; 23(4):270-278. PubMed ID: 28120208
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.