BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 20164785)

  • 1. Comparison of the vasoconstrictor effects of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) and zolmitriptan in human isolated coronary arteries.
    Lynch JJ; Regan CP; Edvinsson L; Hargreaves RJ; Kane SA
    J Cardiovasc Pharmacol; 2010 May; 55(5):518-21. PubMed ID: 20164785
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries.
    Chan KY; Edvinsson L; Eftekhari S; Kimblad PO; Kane SA; Lynch J; Hargreaves RJ; de Vries R; Garrelds IM; van den Bogaerdt AJ; Danser AH; Maassenvandenbrink A
    J Pharmacol Exp Ther; 2010 Sep; 334(3):746-52. PubMed ID: 20573757
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial.
    Ho TW; Ferrari MD; Dodick DW; Galet V; Kost J; Fan X; Leibensperger H; Froman S; Assaid C; Lines C; Koppen H; Winner PK
    Lancet; 2008 Dec; 372(9656):2115-23. PubMed ID: 19036425
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antimigraine efficacy of telcagepant based on patient's historical triptan response.
    Ho TW; Olesen J; Dodick DW; Kost J; Lines C; Ferrari MD
    Headache; 2011 Jan; 51(1):64-72. PubMed ID: 21054362
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecule of the month. Telcagepant.
    Drug News Perspect; 2009 Mar; 22(2):115. PubMed ID: 19330169
    [No Abstract]   [Full Text] [Related]  

  • 6. Sustained pain freedom and no adverse events as an endpoint in clinical trials of acute migraine treatments: application to patient-level data from a trial of the CGRP receptor antagonist, telcagepant, and zolmitriptan.
    Dodick DW; Kost J; Assaid C; Lines C; Ho TW
    Cephalalgia; 2011 Feb; 31(3):296-300. PubMed ID: 20937606
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CGRP-receptor antagonism in migraine treatment.
    Edvinsson L
    Lancet; 2008 Dec; 372(9656):2089-90. PubMed ID: 19036426
    [No Abstract]   [Full Text] [Related]  

  • 8. Long-term tolerability of telcagepant for acute treatment of migraine in a randomized trial.
    Connor KM; Aurora SK; Loeys T; Ashina M; Jones C; Giezek H; Massaad R; Williams-Diaz A; Lines C; Ho TW
    Headache; 2011 Jan; 51(1):73-84. PubMed ID: 21070230
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Excellent tolerability but relatively low initial clinical efficacy of telcagepant in migraine.
    Tfelt-Hansen P
    Headache; 2011 Jan; 51(1):118-23. PubMed ID: 21070229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Telcagepant, a calcitonin gene-related peptide antagonist for the treatment of migraine.
    Tepper SJ; Cleves C
    Curr Opin Investig Drugs; 2009 Jul; 10(7):711-20. PubMed ID: 19579177
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential inhibitory response to telcagepant on αCGRP induced vasorelaxation and intracellular Ca
    Erdling A; Sheykhzade M; Edvinsson L
    J Headache Pain; 2017 Dec; 18(1):61. PubMed ID: 28560541
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigation of CGRP receptors and peptide pharmacology in human coronary arteries. Characterization with a nonpeptide antagonist.
    Hasbak P; Saetrum Opgaard O; Eskesen K; Schifter S; Arendrup H; Longmore J; Edvinsson L
    J Pharmacol Exp Ther; 2003 Jan; 304(1):326-33. PubMed ID: 12490608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries.
    Edvinsson L; Chan KY; Eftekhari S; Nilsson E; de Vries R; Säveland H; Dirven CM; Danser AH; MaassenVanDenBrink A
    Cephalalgia; 2010 Oct; 30(10):1233-40. PubMed ID: 20855369
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Limitations in using peptide drugs to characterize calcitonin gene-related peptide receptors.
    Waugh DJ; Bockman CS; Smith DD; Abel PW
    J Pharmacol Exp Ther; 1999 Jun; 289(3):1419-26. PubMed ID: 10336535
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Efficacy, safety, and tolerability of telcagepant in the treatment of acute migraine: a meta-analysis.
    Cui XP; Ye JX; Lin H; Mu JS; Lin M
    Pain Pract; 2015 Feb; 15(2):124-31. PubMed ID: 24382126
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Examining the binding properties of MK-0974: a CGRP receptor antagonist for the acute treatment of migraine.
    Moore EL; Burgey CS; Paone DV; Shaw AW; Tang YS; Kane SA; Salvatore CA
    Eur J Pharmacol; 2009 Jan; 602(2-3):250-4. PubMed ID: 19084002
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ethanol dilates coronary arteries and increases coronary flow via transient receptor potential vanilloid 1 and calcitonin gene-related peptide.
    Gazzieri D; Trevisani M; Tarantini F; Bechi P; Masotti G; Gensini GF; Castellani S; Marchionni N; Geppetti P; Harrison S
    Cardiovasc Res; 2006 Jun; 70(3):589-99. PubMed ID: 16579978
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries.
    Edvinsson L; Ahnstedt H; Larsen R; Sheykhzade M
    Acta Physiol (Oxf); 2014 Apr; 210(4):811-22. PubMed ID: 24330354
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Randomized, controlled study of telcagepant in patients with migraine and coronary artery disease.
    Ho TW; Ho AP; Chaitman BR; Johnson C; Mathew NT; Kost J; Fan X; Aurora SK; Brandes JL; Fei K; Beebe L; Lines C; Krucoff MW
    Headache; 2012 Feb; 52(2):224-35. PubMed ID: 22221076
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine.
    Salvatore CA; Hershey JC; Corcoran HA; Fay JF; Johnston VK; Moore EL; Mosser SD; Burgey CS; Paone DV; Shaw AW; Graham SL; Vacca JP; Williams TM; Koblan KS; Kane SA
    J Pharmacol Exp Ther; 2008 Feb; 324(2):416-21. PubMed ID: 18039958
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.