279 related articles for article (PubMed ID: 20166932)
1. Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.
Beretta GL; Cossa G; Gatti L; Zunino F; Perego P
Curr Med Chem; 2010; 17(15):1500-8. PubMed ID: 20166932
[TBL] [Abstract][Full Text] [Related]
2. Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase 1 DNA-protein crosslinks and 3'-blocking lesions in the absence of tyrosyl-DNA phosphodiesterase 1 (TDP1).
Tsuda M; Kitamasu K; Kumagai C; Sugiyama K; Nakano T; Ide H
DNA Repair (Amst); 2020; 91-92():102849. PubMed ID: 32460231
[TBL] [Abstract][Full Text] [Related]
3. Tyrosyl-DNA phosphodiesterase as a target for anticancer therapy.
Dexheimer TS; Antony S; Marchand C; Pommier Y
Anticancer Agents Med Chem; 2008 May; 8(4):381-9. PubMed ID: 18473723
[TBL] [Abstract][Full Text] [Related]
4. TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
Zeng Z; Sharma A; Ju L; Murai J; Umans L; Vermeire L; Pommier Y; Takeda S; Huylebroeck D; Caldecott KW; El-Khamisy SF
Nucleic Acids Res; 2012 Sep; 40(17):8371-80. PubMed ID: 22740648
[TBL] [Abstract][Full Text] [Related]
5. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.
Zhang XR; Wang HW; Tang WL; Zhang Y; Yang H; Hu DX; Ravji A; Marchand C; Kiselev E; Ofori-Atta K; Agama K; Pommier Y; An LK
J Med Chem; 2018 Nov; 61(22):9908-9930. PubMed ID: 30336023
[TBL] [Abstract][Full Text] [Related]
6. Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.
Nitiss KC; Malik M; He X; White SW; Nitiss JL
Proc Natl Acad Sci U S A; 2006 Jun; 103(24):8953-8. PubMed ID: 16751265
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of indenoisoquinolines that inhibit both tyrosyl-DNA phosphodiesterase I (Tdp1) and topoisomerase I (Top1).
Conda-Sheridan M; Reddy PV; Morrell A; Cobb BT; Marchand C; Agama K; Chergui A; Renaud A; Stephen AG; Bindu LK; Pommier Y; Cushman M
J Med Chem; 2013 Jan; 56(1):182-200. PubMed ID: 23259865
[TBL] [Abstract][Full Text] [Related]
8. Tyrosyl-DNA Phosphodiesterase 1 Inhibitors: Usnic Acid Enamines Enhance the Cytotoxic Effect of Camptothecin.
Zakharenko A; Luzina O; Koval O; Nilov D; Gushchina I; Dyrkheeva N; Švedas V; Salakhutdinov N; Lavrik O
J Nat Prod; 2016 Nov; 79(11):2961-2967. PubMed ID: 27933897
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer.
Hu DX; Tang WL; Zhang Y; Yang H; Wang W; Agama K; Pommier Y; An LK
J Med Chem; 2021 Jun; 64(11):7617-7629. PubMed ID: 34008967
[TBL] [Abstract][Full Text] [Related]
10. Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions.
Plo I; Liao ZY; Barceló JM; Kohlhagen G; Caldecott KW; Weinfeld M; Pommier Y
DNA Repair (Amst); 2003 Oct; 2(10):1087-100. PubMed ID: 13679147
[TBL] [Abstract][Full Text] [Related]
11. Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding.
Shimizu N; Hamada Y; Morozumi R; Yamamoto J; Iwai S; Sugiyama KI; Ide H; Tsuda M
J Biol Chem; 2023 Aug; 299(8):104988. PubMed ID: 37392847
[TBL] [Abstract][Full Text] [Related]
12. Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.
Comeaux EQ; van Waardenburg RC
Drug Metab Rev; 2014 Nov; 46(4):494-507. PubMed ID: 25327705
[TBL] [Abstract][Full Text] [Related]
13. Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage.
Vance JR; Wilson TE
Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13669-74. PubMed ID: 12368472
[TBL] [Abstract][Full Text] [Related]
14. Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.
Perego P; Cossa G; Tinelli S; Corna E; Carenini N; Gatti L; De Cesare M; Ciusani E; Zunino F; Luison E; Canevari S; Zaffaroni N; Beretta GL
Biochem Pharmacol; 2012 Jan; 83(1):27-36. PubMed ID: 21978643
[TBL] [Abstract][Full Text] [Related]
15. Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.
Liu C; Pouliot JJ; Nash HA
Proc Natl Acad Sci U S A; 2002 Nov; 99(23):14970-5. PubMed ID: 12397185
[TBL] [Abstract][Full Text] [Related]
16. Correlation between topoisomerase I and tyrosyl-DNA phosphodiesterase 1 activities in non-small cell lung cancer tissue.
Jakobsen AK; Lauridsen KL; Samuel EB; Proszek J; Knudsen BR; Hager H; Stougaard M
Exp Mol Pathol; 2015 Aug; 99(1):56-64. PubMed ID: 25987486
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of nitrated 7-, 8-, 9-, and 10-hydroxyindenoisoquinolines as potential dual topoisomerase I (Top1)-tyrosyl-DNA phosphodiesterase I (TDP1) inhibitors.
Nguyen TX; Abdelmalak M; Marchand C; Agama K; Pommier Y; Cushman M
J Med Chem; 2015 Apr; 58(7):3188-208. PubMed ID: 25811317
[TBL] [Abstract][Full Text] [Related]
18. Hereditary ataxia SCAN1 cells are defective for the repair of transcription-dependent topoisomerase I cleavage complexes.
Miao ZH; Agama K; Sordet O; Povirk L; Kohn KW; Pommier Y
DNA Repair (Amst); 2006 Dec; 5(12):1489-94. PubMed ID: 16935573
[TBL] [Abstract][Full Text] [Related]
19. TDP1-independent pathways in the process and repair of TOP1-induced DNA damage.
Zhang H; Xiong Y; Su D; Wang C; Srivastava M; Tang M; Feng X; Huang M; Chen Z; Chen J
Nat Commun; 2022 Jul; 13(1):4240. PubMed ID: 35869071
[TBL] [Abstract][Full Text] [Related]
20. TDP1 overexpression in human cells counteracts DNA damage mediated by topoisomerases I and II.
Barthelmes HU; Habermeyer M; Christensen MO; Mielke C; Interthal H; Pouliot JJ; Boege F; Marko D
J Biol Chem; 2004 Dec; 279(53):55618-25. PubMed ID: 15494395
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
