BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

798 related articles for article (PubMed ID: 20167603)

  • 1. DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
    Guo X; Williams JG; Schug TT; Li X
    J Biol Chem; 2010 Apr; 285(17):13223-32. PubMed ID: 20167603
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1.
    Back JH; Rezvani HR; Zhu Y; Guyonnet-Duperat V; Athar M; Ratner D; Kim AL
    J Biol Chem; 2011 May; 286(21):19100-8. PubMed ID: 21471201
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
    Park J; Oh Y; Yoo L; Jung MS; Song WJ; Lee SH; Seo H; Chung KC
    J Biol Chem; 2010 Oct; 285(41):31895-906. PubMed ID: 20696760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation.
    Yuan F; Xie Q; Wu J; Bai Y; Mao B; Dong Y; Bi W; Ji G; Tao W; Wang Y; Yuan Z
    J Biol Chem; 2011 Mar; 286(9):6940-5. PubMed ID: 21212262
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p53 downregulates Down syndrome-associated DYRK1A through miR-1246.
    Zhang Y; Liao JM; Zeng SX; Lu H
    EMBO Rep; 2011 Jun; 12(8):811-7. PubMed ID: 21637297
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DYRK1A: a down syndrome-related dual protein kinase with a versatile role in tumorigenesis.
    Laham AJ; Saber-Ayad M; El-Awady R
    Cell Mol Life Sci; 2021 Jan; 78(2):603-619. PubMed ID: 32870330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
    García-Cerro S; Rueda N; Vidal V; Lantigua S; Martínez-Cué C
    Neurobiol Dis; 2017 Oct; 106():76-88. PubMed ID: 28647555
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HIPK2 restricts SIRT1 activity upon severe DNA damage by a phosphorylation-controlled mechanism.
    Conrad E; Polonio-Vallon T; Meister M; Matt S; Bitomsky N; Herbel C; Liebl M; Greiner V; Kriznik B; Schumacher S; Krieghoff-Henning E; Hofmann TG
    Cell Death Differ; 2016 Jan; 23(1):110-22. PubMed ID: 26113041
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation.
    Soppa U; Schumacher J; Florencio Ortiz V; Pasqualon T; Tejedor FJ; Becker W
    Cell Cycle; 2014; 13(13):2084-100. PubMed ID: 24806449
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease.
    Barallobre MJ; Perier C; Bové J; Laguna A; Delabar JM; Vila M; Arbonés ML
    Cell Death Dis; 2014 Jun; 5(6):e1289. PubMed ID: 24922073
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HIPK2 modulates p53 activity towards pro-apoptotic transcription.
    Puca R; Nardinocchi L; Sacchi A; Rechavi G; Givol D; D'Orazi G
    Mol Cancer; 2009 Oct; 8():85. PubMed ID: 19828042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.
    Adayev T; Chen-Hwang MC; Murakami N; Lee E; Bolton DC; Hwang YW
    Biochemistry; 2007 Jun; 46(25):7614-24. PubMed ID: 17536841
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
    Soundararajan M; Roos AK; Savitsky P; Filippakopoulos P; Kettenbach AN; Olsen JV; Gerber SA; Eswaran J; Knapp S; Elkins JM
    Structure; 2013 Jun; 21(6):986-96. PubMed ID: 23665168
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells.
    Zu Y; Liu L; Lee MY; Xu C; Liang Y; Man RY; Vanhoutte PM; Wang Y
    Circ Res; 2010 Apr; 106(8):1384-93. PubMed ID: 20203304
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration.
    Branchi I; Bichler Z; Minghetti L; Delabar JM; Malchiodi-Albedi F; Gonzalez MC; Chettouh Z; Nicolini A; Chabert C; Smith DJ; Rubin EM; Migliore-Samour D; Alleva E
    J Neuropathol Exp Neurol; 2004 May; 63(5):429-40. PubMed ID: 15198122
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation.
    Jung MS; Park JH; Ryu YS; Choi SH; Yoon SH; Kwen MY; Oh JY; Song WJ; Chung SH
    J Biol Chem; 2011 Nov; 286(46):40401-12. PubMed ID: 21965663
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dyrk kinases regulate phosphorylation of doublecortin, cytoskeletal organization, and neuronal morphology.
    Slepak TI; Salay LD; Lemmon VP; Bixby JL
    Cytoskeleton (Hoboken); 2012 Jul; 69(7):514-27. PubMed ID: 22359282
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of dual specificity kinase activity of DYRK1A.
    Walte A; Rüben K; Birner-Gruenberger R; Preisinger C; Bamberg-Lemper S; Hilz N; Bracher F; Becker W
    FEBS J; 2013 Sep; 280(18):4495-511. PubMed ID: 23809146
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation.
    Lee YH; Im E; Hyun M; Park J; Chung KC
    J Biol Chem; 2021; 296():100245. PubMed ID: 33380426
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications.
    Abbassi R; Johns TG; Kassiou M; Munoz L
    Pharmacol Ther; 2015 Jul; 151():87-98. PubMed ID: 25795597
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 40.