140 related articles for article (PubMed ID: 20170099)
1. 5-Cyclic amine-3-arylsulfonylindazoles as novel 5-HT6 receptor antagonists.
Haydar SN; Yun H; Andrae PM; Mattes J; Zhang J; Kramer A; Smith DL; Huselton C; Graf R; Aschmies S; Schechter LE; Comery TA; Robichaud AJ
J Med Chem; 2010 Mar; 53(6):2521-7. PubMed ID: 20170099
[TBL] [Abstract][Full Text] [Related]
2. A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties.
Moss N; Choi Y; Cogan D; Flegg A; Kahrs A; Loke P; Meyn O; Nagaraja R; Napier S; Parker A; Thomas Peterson J; Ramsden P; Sarko C; Skow D; Tomlinson J; Tye H; Whitaker M
Bioorg Med Chem Lett; 2009 Apr; 19(8):2206-10. PubMed ID: 19307114
[TBL] [Abstract][Full Text] [Related]
3. 5-Piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists.
Liu KG; Robichaud AJ; Bernotas RC; Yan Y; Lo JR; Zhang MY; Hughes ZA; Huselton C; Zhang GM; Zhang JY; Kowal DM; Smith DL; Schechter LE; Comery TA
J Med Chem; 2010 Nov; 53(21):7639-46. PubMed ID: 20932009
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and pharmacological evaluation of aryl aminosulfonamide derivatives as potent 5-HT(6) receptor antagonists.
Nirogi RV; Daulatabad AV; Parandhama G; Mohammad S; Sastri KR; Shinde AK; Dubey PK
Bioorg Med Chem Lett; 2010 Aug; 20(15):4440-3. PubMed ID: 20594839
[TBL] [Abstract][Full Text] [Related]
5. 3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT(6) receptor modulators.
Bernotas RC; Antane S; Shenoy R; Le VD; Chen P; Harrison BL; Robichaud AJ; Zhang GM; Smith D; Schechter LE
Bioorg Med Chem Lett; 2010 Mar; 20(5):1657-60. PubMed ID: 20138763
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and serotonergic activity of substituted 2, N-benzylcarboxamido-5-(2-ethyl-1-dioxoimidazolidinyl)-N, N-dimethyltryptamine derivatives: novel antagonists for the vascular 5-HT(1B)-like receptor.
Moloney GP; Martin GR; Mathews N; Milne A; Hobbs H; Dodsworth S; Sang PY; Knight C; Williams M; Maxwell M; Glen RC
J Med Chem; 1999 Jul; 42(14):2504-26. PubMed ID: 10411472
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
Hirokawa Y; Fujiwara I; Suzuki K; Harada H; Yoshikawa T; Yoshida N; Kato S
J Med Chem; 2003 Feb; 46(5):702-15. PubMed ID: 12593651
[TBL] [Abstract][Full Text] [Related]
8. Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands.
Raubo P; Beer MS; Hunt PA; Huscroft IT; London C; Stanton JA; Kulagowski JJ
Bioorg Med Chem Lett; 2006 Mar; 16(5):1255-8. PubMed ID: 16337790
[TBL] [Abstract][Full Text] [Related]
9. Indole-3-piperazinyl derivatives: novel chemical class of 5-HT(6) receptor antagonists.
Nirogi RV; Deshpande AD; Kambhampati R; Badange RK; Kota L; Daulatabad AV; Shinde AK; Ahmad I; Kandikere V; Jayarajan P; Dubey PK
Bioorg Med Chem Lett; 2011 Jan; 21(1):346-9. PubMed ID: 21134749
[TBL] [Abstract][Full Text] [Related]
10. Novel 1-(azacyclyl)-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines as 5-HT6 agonists and antagonists.
Elokdah H; Li D; McFarlane G; Bernotas RC; Robichaud AJ; Magolda RL; Zhang GM; Smith D; Schechter LE
Bioorg Med Chem; 2007 Sep; 15(18):6208-26. PubMed ID: 17624788
[TBL] [Abstract][Full Text] [Related]
11. Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.
Cappelli A; Anzini M; Vomero S; Canullo L; Mennuni L; Makovec F; Doucet E; Hamon M; Menziani MC; De Benedetti PG; Bruni G; Romeo MR; Giorgi G; Donati A
J Med Chem; 1999 May; 42(9):1556-75. PubMed ID: 10229626
[TBL] [Abstract][Full Text] [Related]
12. Discrimination in 5-HT(3) receptor binding in murine brain and cultured cell preparations.
Zhang ZJ; Trivedi BL; de Paulis T; Schmidt DE; Hewlett WA
Naunyn Schmiedebergs Arch Pharmacol; 2002 Feb; 365(2):123-32. PubMed ID: 11819030
[TBL] [Abstract][Full Text] [Related]
13. Novel and selective 5-HT2C/2B receptor antagonists as potential anxiolytic agents: synthesis, quantitative structure-activity relationships, and molecular modeling of substituted 1-(3-pyridylcarbamoyl)indolines.
Bromidge SM; Dabbs S; Davies DT; Duckworth DM; Forbes IT; Ham P; Jones GE; King FD; Saunders DV; Starr S; Thewlis KM; Wyman PA; Blaney FE; Naylor CB; Bailey F; Blackburn TP; Holland V; Kennett GA; Riley GJ; Wood MD
J Med Chem; 1998 May; 41(10):1598-612. PubMed ID: 9572885
[TBL] [Abstract][Full Text] [Related]
14. Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists.
Rudolph DA; Dvorak CA; Dvorak L; Nepomuceno D; Bonaventure P; Lovenberg TW; Carruthers NI
Bioorg Med Chem Lett; 2011 Jan; 21(1):42-4. PubMed ID: 21159507
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists.
Moritomo A; Yamada H; Watanabe T; Itahana H; Akuzawa S; Okada M; Ohta M
Bioorg Med Chem; 2013 Dec; 21(24):7841-52. PubMed ID: 24189186
[TBL] [Abstract][Full Text] [Related]
16. 1-Sulfonylindazoles as potent and selective 5-HT6 ligands.
Liu KG; Lo JR; Comery TA; Zhang GM; Zhang JY; Kowal DM; Smith DL; Di L; Kerns EH; Schechter LE; Robichaud AJ
Bioorg Med Chem Lett; 2009 May; 19(9):2413-5. PubMed ID: 19345582
[TBL] [Abstract][Full Text] [Related]
17. Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives.
Cappelli A; Anzini M; Vomero S; Mennuni L; Makovec F; Doucet E; Hamon M; Bruni G; Romeo MR; Menziani MC; De Benedetti PG; Langer T
J Med Chem; 1998 Feb; 41(5):728-41. PubMed ID: 9513601
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationships of potent and orally active 5-HT4 receptor antagonists: indazole and benzimidazolone derivatives.
Schaus JM; Thompson DC; Bloomquist WE; Susemichel AD; Calligaro DO; Cohen ML
J Med Chem; 1998 May; 41(11):1943-55. PubMed ID: 9599243
[TBL] [Abstract][Full Text] [Related]
19. Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: identification of a potent and selective 5-HT₆ receptor antagonist showing activity in rat social recognition test.
Tripathy R; McHugh RJ; Bacon ER; Salvino JM; Morton GC; Aimone LD; Huang Z; Mathiasen JR; DiCamillo A; Huffman MJ; McKenna BA; Kopec K; Lu LD; Qian J; Angeles TS; Connors T; Spais C; Holskin B; Duzic E; Schaffhauser H; Rossé GC
Bioorg Med Chem Lett; 2012 Feb; 22(3):1421-6. PubMed ID: 22226656
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and SAR of tolylamine 5-HT6 antagonists.
Singer JM; Wilson MW; Johnson PD; Graham SR; Cooke LW; Roof RL; Boxer PA; Gold LH; Meltzer LT; Janssen A; Roush N; Campbell JE; Su TZ; Hurst SI; Stoner CL; Schwarz JB
Bioorg Med Chem Lett; 2009 May; 19(9):2409-12. PubMed ID: 19346128
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
