BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 20171273)

  • 1. Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis.
    Puca R; Nardinocchi L; Starace G; Rechavi G; Sacchi A; Givol D; D'Orazi G
    Free Radic Biol Med; 2010 May; 48(10):1338-46. PubMed ID: 20171273
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HIPK2 modulates p53 activity towards pro-apoptotic transcription.
    Puca R; Nardinocchi L; Sacchi A; Rechavi G; Givol D; D'Orazi G
    Mol Cancer; 2009 Oct; 8():85. PubMed ID: 19828042
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage.
    Di Stefano V; Soddu S; Sacchi A; D'Orazi G
    Oncogene; 2005 Aug; 24(35):5431-42. PubMed ID: 15897882
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Downregulation of Sirt1 by antisense oligonucleotides induces apoptosis and enhances radiation sensitization in A549 lung cancer cells.
    Sun Y; Sun D; Li F; Tian L; Li C; Li L; Lin R; Wang S
    Lung Cancer; 2007 Oct; 58(1):21-9. PubMed ID: 17624472
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells.
    Puca R; Nardinocchi L; Givol D; D'Orazi G
    Oncogene; 2010 Aug; 29(31):4378-87. PubMed ID: 20514025
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells.
    Puca R; Nardinocchi L; Pistritto G; D'Orazi G
    Gynecol Oncol; 2008 Jun; 109(3):403-10. PubMed ID: 18395248
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc.
    Puca R; Nardinocchi L; Bossi G; Sacchi A; Rechavi G; Givol D; D'Orazi G
    Exp Cell Res; 2009 Jan; 315(1):67-75. PubMed ID: 18996371
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death.
    Li Q; Wang X; Wu X; Rui Y; Liu W; Wang J; Wang X; Liou YC; Ye Z; Lin SC
    Cancer Res; 2007 Jan; 67(1):66-74. PubMed ID: 17210684
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HIPK2 restricts SIRT1 activity upon severe DNA damage by a phosphorylation-controlled mechanism.
    Conrad E; Polonio-Vallon T; Meister M; Matt S; Bitomsky N; Herbel C; Liebl M; Greiner V; Kriznik B; Schumacher S; Krieghoff-Henning E; Hofmann TG
    Cell Death Differ; 2016 Jan; 23(1):110-22. PubMed ID: 26113041
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Negative regulation of beta4 integrin transcription by homeodomain-interacting protein kinase 2 and p53 impairs tumor progression.
    Bon G; Di Carlo SE; Folgiero V; Avetrani P; Lazzari C; D'Orazi G; Brizzi MF; Sacchi A; Soddu S; Blandino G; Mottolese M; Falcioni R
    Cancer Res; 2009 Jul; 69(14):5978-86. PubMed ID: 19567674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology.
    Robers MB; Loh C; Carlson CB; Yang H; Frey EA; Hermanson SB; Bi K
    Mol Biosyst; 2011 Jan; 7(1):59-66. PubMed ID: 20931131
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation.
    Rui Y; Xu Z; Lin S; Li Q; Rui H; Luo W; Zhou HM; Cheung PY; Wu Z; Ye Z; Li P; Han J; Lin SC
    EMBO J; 2004 Nov; 23(23):4583-94. PubMed ID: 15526030
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses.
    Chen WY; Wang DH; Yen RC; Luo J; Gu W; Baylin SB
    Cell; 2005 Nov; 123(3):437-48. PubMed ID: 16269335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence.
    Jang SY; Kim SY; Bae YS
    FEBS Lett; 2011 Nov; 585(21):3360-6. PubMed ID: 21968188
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network.
    Audrito V; Vaisitti T; Rossi D; Gottardi D; D'Arena G; Laurenti L; Gaidano G; Malavasi F; Deaglio S
    Cancer Res; 2011 Jul; 71(13):4473-83. PubMed ID: 21565980
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Function of the SIRT1 protein deacetylase in cancer.
    Stünkel W; Peh BK; Tan YC; Nayagam VM; Wang X; Salto-Tellez M; Ni B; Entzeroth M; Wood J
    Biotechnol J; 2007 Nov; 2(11):1360-8. PubMed ID: 17806102
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation.
    Kume S; Haneda M; Kanasaki K; Sugimoto T; Araki S; Isono M; Isshiki K; Uzu T; Kashiwagi A; Koya D
    Free Radic Biol Med; 2006 Jun; 40(12):2175-82. PubMed ID: 16785031
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown.
    Puca R; Nardinocchi L; Gal H; Rechavi G; Amariglio N; Domany E; Notterman DA; Scarsella M; Leonetti C; Sacchi A; Blandino G; Givol D; D'Orazi G
    Cancer Res; 2008 May; 68(10):3707-14. PubMed ID: 18483253
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.
    Lara E; Mai A; Calvanese V; Altucci L; Lopez-Nieva P; Martinez-Chantar ML; Varela-Rey M; Rotili D; Nebbioso A; Ropero S; Montoya G; Oyarzabal J; Velasco S; Serrano M; Witt M; Villar-Garea A; Imhof A; Mato JM; Esteller M; Fraga MF
    Oncogene; 2009 Feb; 28(6):781-91. PubMed ID: 19060927
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sirt1 attenuates camptothecin-induced apoptosis through caspase-3 pathway in porcine preadipocytes.
    Pang WJ; Xiong Y; Wang Y; Tong Q; Yang GS
    Exp Cell Res; 2013 Mar; 319(5):670-83. PubMed ID: 23313858
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.