These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 20171894)

  • 21. Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity.
    Rizzo S; Rivière C; Piazzi L; Bisi A; Gobbi S; Bartolini M; Andrisano V; Morroni F; Tarozzi A; Monti JP; Rampa A
    J Med Chem; 2008 May; 51(10):2883-6. PubMed ID: 18419109
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
    Bautista-Aguilera OM; Esteban G; Chioua M; Nikolic K; Agbaba D; Moraleda I; Iriepa I; Soriano E; Samadi A; Unzeta M; Marco-Contelles J
    Drug Des Devel Ther; 2014; 8():1893-910. PubMed ID: 25378907
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush.
    Rosini M; Simoni E; Bartolini M; Cavalli A; Ceccarini L; Pascu N; McClymont DW; Tarozzi A; Bolognesi ML; Minarini A; Tumiatti V; Andrisano V; Mellor IR; Melchiorre C
    J Med Chem; 2008 Aug; 51(15):4381-4. PubMed ID: 18605718
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: synthesis, biological assessment, and molecular modeling.
    Samadi A; Estrada M; Pérez C; Rodríguez-Franco MI; Iriepa I; Moraleda I; Chioua M; Marco-Contelles J
    Eur J Med Chem; 2012 Nov; 57():296-301. PubMed ID: 23078965
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Pterostilbene-O-acetamidoalkylbenzylamines derivatives as novel dual inhibitors of cholinesterase with anti-β-amyloid aggregation and antioxidant properties for the treatment of Alzheimer's disease.
    Li Y; Qiang X; Li Y; Yang X; Luo L; Xiao G; Cao Z; Tan Z; Deng Y
    Bioorg Med Chem Lett; 2016 Apr; 26(8):2035-9. PubMed ID: 26947607
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Quinolone-benzylpiperidine derivatives as novel acetylcholinesterase inhibitor and antioxidant hybrids for Alzheimer disease.
    Pudlo M; Luzet V; Ismaïli L; Tomassoli I; Iutzeler A; Refouvelet B
    Bioorg Med Chem; 2014 Apr; 22(8):2496-507. PubMed ID: 24657052
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.
    Muñoz-Ruiz P; Rubio L; García-Palomero E; Dorronsoro I; del Monte-Millán M; Valenzuela R; Usán P; de Austria C; Bartolini M; Andrisano V; Bidon-Chanal A; Orozco M; Luque FJ; Medina M; Martínez A
    J Med Chem; 2005 Nov; 48(23):7223-33. PubMed ID: 16279781
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Protective effect of donepezil against Abeta(1-40) neurotoxicity in rat septal neurons.
    Kimura M; Akasofu S; Ogura H; Sawada K
    Brain Res; 2005 Jun; 1047(1):72-84. PubMed ID: 15893738
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds.
    Piazzi L; Cavalli A; Colizzi F; Belluti F; Bartolini M; Mancini F; Recanatini M; Andrisano V; Rampa A
    Bioorg Med Chem Lett; 2008 Jan; 18(1):423-6. PubMed ID: 17998161
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Donepezilium oxalate trihydrate, a therapeutic agent for Alzheimer's disease.
    Ravikumar K; Sridhar B; Sathe DG; Naidu AV; Sawant KD
    Acta Crystallogr C; 2006 Dec; 62(Pt 12):o681-3. PubMed ID: 17148911
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
    Camps P; Formosa X; Galdeano C; Muñoz-Torrero D; Ramírez L; Gómez E; Isambert N; Lavilla R; Badia A; Clos MV; Bartolini M; Mancini F; Andrisano V; Arce MP; Rodríguez-Franco MI; Huertas O; Dafni T; Luque FJ
    J Med Chem; 2009 Sep; 52(17):5365-79. PubMed ID: 19663388
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
    Dias Viegas FP; de Freitas Silva M; Divino da Rocha M; Castelli MR; Riquiel MM; Machado RP; Vaz SM; Simões de Lima LM; Mancini KC; Marques de Oliveira PC; Morais ÉP; Gontijo VS; da Silva FMR; D'Alincourt da Fonseca Peçanha D; Castro NG; Neves GA; Giusti-Paiva A; Vilela FC; Orlandi L; Camps I; Veloso MP; Leomil Coelho LF; Ionta M; Ferreira-Silva GÁ; Pereira RM; Dardenne LE; Guedes IA; de Oliveira Carneiro Junior W; Quaglio Bellozi PM; Pinheiro de Oliveira AC; Ferreira FF; Pruccoli L; Tarozzi A; Viegas C
    Eur J Med Chem; 2018 Mar; 147():48-65. PubMed ID: 29421570
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Multiple Ligands Targeting Cholinesterases and β-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore.
    Szałaj N; Bajda M; Dudek K; Brus B; Gobec S; Malawska B
    Arch Pharm (Weinheim); 2015 Aug; 348(8):556-63. PubMed ID: 26032855
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors.
    Parnetti L; Amici S; Lanari A; Romani C; Antognelli C; Andreasen N; Minthon L; Davidsson P; Pottel H; Blennow K; Gallai V
    Neurol Sci; 2002 Sep; 23 Suppl 2():S95-6. PubMed ID: 12548360
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil.
    van Greunen DG; Cordier W; Nell M; van der Westhuyzen C; Steenkamp V; Panayides JL; Riley DL
    Eur J Med Chem; 2017 Feb; 127():671-690. PubMed ID: 27823887
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.
    Catto M; Berezin AA; Lo Re D; Loizou G; Demetriades M; De Stradis A; Campagna F; Koutentis PA; Carotti A
    Eur J Med Chem; 2012 Dec; 58():84-97. PubMed ID: 23108363
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.
    Joubert J; Foka GB; Repsold BP; Oliver DW; Kapp E; Malan SF
    Eur J Med Chem; 2017 Jan; 125():853-864. PubMed ID: 27744252
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues.
    Bolognesi ML; Bartolini M; Cavalli A; Andrisano V; Rosini M; Minarini A; Melchiorre C
    J Med Chem; 2004 Nov; 47(24):5945-52. PubMed ID: 15537349
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase.
    Catto M; Pisani L; Leonetti F; Nicolotti O; Pesce P; Stefanachi A; Cellamare S; Carotti A
    Bioorg Med Chem; 2013 Jan; 21(1):146-52. PubMed ID: 23199476
    [TBL] [Abstract][Full Text] [Related]  

  • 40. From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold.
    Rampa A; Mancini F; De Simone A; Falchi F; Belluti F; Di Martino RM; Gobbi S; Andrisano V; Tarozzi A; Bartolini M; Cavalli A; Bisi A
    Bioorg Med Chem Lett; 2015 Jul; 25(14):2804-8. PubMed ID: 26003339
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.