638 related articles for article (PubMed ID: 20175530)
1. Intramolecular hydrogen bonding in medicinal chemistry.
Kuhn B; Mohr P; Stahl M
J Med Chem; 2010 Mar; 53(6):2601-11. PubMed ID: 20175530
[TBL] [Abstract][Full Text] [Related]
2. Kinase inhibitors and the case for CH...O hydrogen bonds in protein-ligand binding.
Pierce AC; Sandretto KL; Bemis GW
Proteins; 2002 Dec; 49(4):567-76. PubMed ID: 12402365
[TBL] [Abstract][Full Text] [Related]
3. Small molecule conformational preferences derived from crystal structure data. A medicinal chemistry focused analysis.
Brameld KA; Kuhn B; Reuter DC; Stahl M
J Chem Inf Model; 2008 Jan; 48(1):1-24. PubMed ID: 18183967
[TBL] [Abstract][Full Text] [Related]
4. In silico identification of bioisosteric functional groups.
Ertl P
Curr Opin Drug Discov Devel; 2007 May; 10(3):281-8. PubMed ID: 17554854
[TBL] [Abstract][Full Text] [Related]
5. Fluorine in medicinal chemistry.
Böhm HJ; Banner D; Bendels S; Kansy M; Kuhn B; Müller K; Obst-Sander U; Stahl M
Chembiochem; 2004 May; 5(5):637-43. PubMed ID: 15122635
[TBL] [Abstract][Full Text] [Related]
6. Fluorine bonding--how does it work in protein-ligand interactions?
Zhou P; Zou J; Tian F; Shang Z
J Chem Inf Model; 2009 Oct; 49(10):2344-55. PubMed ID: 19788294
[TBL] [Abstract][Full Text] [Related]
7. Recognition of LXXLL by ligand binding domain of the Farnesoid X receptor in molecular dynamics simulation.
Zhang T; Dong XC; Chen MB
J Chem Inf Model; 2006; 46(6):2623-30. PubMed ID: 17125202
[TBL] [Abstract][Full Text] [Related]
8. N-H...O, O-H...O, and C-H...O hydrogen bonds in protein-ligand complexes: strong and weak interactions in molecular recognition.
Sarkhel S; Desiraju GR
Proteins; 2004 Feb; 54(2):247-59. PubMed ID: 14696187
[TBL] [Abstract][Full Text] [Related]
9. Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
Krajewski WW; Collins R; Holmberg-Schiavone L; Jones TA; Karlberg T; Mowbray SL
J Mol Biol; 2008 Jan; 375(1):217-28. PubMed ID: 18005987
[TBL] [Abstract][Full Text] [Related]
10. Statistical and molecular dynamics studies of buried waters in globular proteins.
Park S; Saven JG
Proteins; 2005 Aug; 60(3):450-63. PubMed ID: 15937899
[TBL] [Abstract][Full Text] [Related]
11. The hydrogen bond environments of 1H-tetrazole and tetrazolate rings: the structural basis for tetrazole-carboxylic acid bioisosterism.
Allen FH; Groom CR; Liebeschuetz JW; Bardwell DA; Olsson TS; Wood PA
J Chem Inf Model; 2012 Mar; 52(3):857-66. PubMed ID: 22303876
[TBL] [Abstract][Full Text] [Related]
12. [Strategy of molecular design of drugs: the unification of macro-properties and micro-structures of a molecule].
Guo ZR
Yao Xue Xue Bao; 2008 Mar; 43(3):227-33. PubMed ID: 18630256
[TBL] [Abstract][Full Text] [Related]
13. Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4.
Lee H; Reyes VM; Kraut J
Biochemistry; 1996 Jun; 35(22):7012-20. PubMed ID: 8679526
[TBL] [Abstract][Full Text] [Related]
14. Metal complexes in medicinal chemistry: new vistas and challenges in drug design.
Thompson KH; Orvig C
Dalton Trans; 2006 Feb; (6):761-4. PubMed ID: 16437168
[TBL] [Abstract][Full Text] [Related]
15. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
Katz BA; Elrod K; Luong C; Rice MJ; Mackman RL; Sprengeler PA; Spencer J; Hataye J; Janc J; Link J; Litvak J; Rai R; Rice K; Sideris S; Verner E; Young W
J Mol Biol; 2001 Apr; 307(5):1451-86. PubMed ID: 11292354
[TBL] [Abstract][Full Text] [Related]
16. Strong and weak hydrogen bonds in protein-ligand complexes of kinases: a comparative study.
Panigrahi SK
Amino Acids; 2008 May; 34(4):617-33. PubMed ID: 18180869
[TBL] [Abstract][Full Text] [Related]
17. Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist.
Feng S; Yang M; Zhang Z; Wang Z; Hong D; Richter H; Benson GM; Bleicher K; Grether U; Martin RE; Plancher JM; Kuhn B; Rudolph MG; Chen L
Bioorg Med Chem Lett; 2009 May; 19(9):2595-8. PubMed ID: 19328688
[TBL] [Abstract][Full Text] [Related]
18. Ranking poses in structure-based lead discovery and optimization: current trends in scoring function development.
Rajamani R; Good AC
Curr Opin Drug Discov Devel; 2007 May; 10(3):308-15. PubMed ID: 17554857
[TBL] [Abstract][Full Text] [Related]
19. The graphical representation of ADME-related molecule properties for medicinal chemists.
Ritchie TJ; Ertl P; Lewis R
Drug Discov Today; 2011 Jan; 16(1-2):65-72. PubMed ID: 21074634
[TBL] [Abstract][Full Text] [Related]
20. Physics-based methods for studying protein-ligand interactions.
Huang N; Jacobson MP
Curr Opin Drug Discov Devel; 2007 May; 10(3):325-31. PubMed ID: 17554859
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
