89 related articles for article (PubMed ID: 20182728)
1. The anti-cancer peptide, PNC-27, induces tumor cell lysis as the intact peptide.
Sookraj KA; Bowne WB; Adler V; Sarafraz-Yazdi E; Michl J; Pincus MR
Cancer Chemother Pharmacol; 2010 Jul; 66(2):325-31. PubMed ID: 20182728
[TBL] [Abstract][Full Text] [Related]
2. The anti-cancer peptide, PNC-27, induces tumor cell necrosis of a poorly differentiated non-solid tissue human leukemia cell line that depends on expression of HDM-2 in the plasma membrane of these cells.
Davitt K; Babcock BD; Fenelus M; Poon CK; Sarkar A; Trivigno V; Zolkind PA; Matthew SM; Grin'kina N; Orynbayeva Z; Shaikh MF; Adler V; Michl J; Sarafraz-Yazdi E; Pincus MR; Bowne WB
Ann Clin Lab Sci; 2014; 44(3):241-8. PubMed ID: 25117093
[TBL] [Abstract][Full Text] [Related]
3. The penetratin sequence in the anticancer PNC-28 peptide causes tumor cell necrosis rather than apoptosis of human pancreatic cancer cells.
Bowne WB; Sookraj KA; Vishnevetsky M; Adler V; Sarafraz-Yazdi E; Lou S; Koenke J; Shteyler V; Ikram K; Harding M; Bluth MH; Ng M; Brandt-Rauf PW; Hannan R; Bradu S; Zenilman ME; Michl J; Pincus MR
Ann Surg Oncol; 2008 Dec; 15(12):3588-600. PubMed ID: 18931881
[TBL] [Abstract][Full Text] [Related]
4. Anticancer peptide PNC-27 adopts an HDM-2-binding conformation and kills cancer cells by binding to HDM-2 in their membranes.
Sarafraz-Yazdi E; Bowne WB; Adler V; Sookraj KA; Wu V; Shteyler V; Patel H; Oxbury W; Brandt-Rauf P; Zenilman ME; Michl J; Pincus MR
Proc Natl Acad Sci U S A; 2010 Feb; 107(5):1918-23. PubMed ID: 20080680
[TBL] [Abstract][Full Text] [Related]
5. Anti-Cancer Tumor Cell Necrosis of Epithelial Ovarian Cancer Cell Lines Depends on High Expression of HDM-2 Protein in Their Membranes.
Thadi A; Gleeson EM; Khalili M; Shaikh MF; Goldstein E; Morano WF; Daniels LM; Grandhi N; Glatthorn H; Richard SD; Campbell PM; Sarafraz-Yazdi E; Pincus MR; Bowne WB
Ann Clin Lab Sci; 2020 Sep; 50(5):611-624. PubMed ID: 33067207
[TBL] [Abstract][Full Text] [Related]
6. Targeting Membrane HDM-2 by PNC-27 Induces Necrosis in Leukemia Cells But Not in Normal Hematopoietic Cells.
Thadi A; Lewis L; Goldstein E; Aggarwal A; Khalili M; Steele L; Polyak B; Seydafkan S; Bluth MH; Ward KA; Styler M; Campbell PM; Pincus MR; Bowne WB
Anticancer Res; 2020 Sep; 40(9):4857-4867. PubMed ID: 32878773
[TBL] [Abstract][Full Text] [Related]
7. Anti-Cancer Peptide PNC-27 Kills Cancer Cells by Unique Interactions with Plasma Membrane-Bound hdm-2 and with Mitochondrial Membranes Causing Mitochondrial Disruption.
Krzesaj P; Adler V; Feinman RD; Miller A; Silberstein M; Yazdi E; Pincus MR
Ann Clin Lab Sci; 2024 Mar; 54(2):137-148. PubMed ID: 38802154
[TBL] [Abstract][Full Text] [Related]
8. PNC-27, a Chimeric p53-Penetratin Peptide Binds to HDM-2 in a p53 Peptide-like Structure, Induces Selective Membrane-Pore Formation and Leads to Cancer Cell Lysis.
Sarafraz-Yazdi E; Mumin S; Cheung D; Fridman D; Lin B; Wong L; Rosal R; Rudolph R; Frenkel M; Thadi A; Morano WF; Bowne WB; Pincus MR; Michl J
Biomedicines; 2022 Apr; 10(5):. PubMed ID: 35625682
[TBL] [Abstract][Full Text] [Related]
9. Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site.
Do TN; Rosal RV; Drew L; Raffo AJ; Michl J; Pincus MR; Friedman FK; Petrylak DP; Cassai N; Szmulewicz J; Sidhu G; Fine RL; Brandt-Rauf PW
Oncogene; 2003 Mar; 22(10):1431-44. PubMed ID: 12629507
[TBL] [Abstract][Full Text] [Related]
10. PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo.
Michl J; Scharf B; Schmidt A; Huynh C; Hannan R; von Gizycki H; Friedman FK; Brandt-Rauf P; Fine RL; Pincus MR
Int J Cancer; 2006 Oct; 119(7):1577-85. PubMed ID: 16688716
[TBL] [Abstract][Full Text] [Related]
11. Anti-cancer peptides from ras-p21 and p53 proteins.
Pincus MR; Fenelus M; Sarafraz-Yazdi E; Adler V; Bowne W; Michl J
Curr Pharm Des; 2011; 17(25):2677-98. PubMed ID: 21728981
[TBL] [Abstract][Full Text] [Related]
12. Molecular Targeting of H/MDM-2 Oncoprotein in Human Colon Cancer Cells and Stem-like Colonic Epithelial-derived Progenitor Cells.
Thadi A; Morano WF; Khalili M; Babcock BD; Shaikh MF; Foster DS; Piazza Y; Gleeson EM; Goldstein E; Steele L; Campbell PM; Lin BO; Pincus MR; Bowne WB
Anticancer Res; 2021 Jan; 41(1):27-42. PubMed ID: 33419797
[TBL] [Abstract][Full Text] [Related]
13. BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53.
Basma H; El-Refaey H; Sgagias MK; Cowan KH; Luo X; Cheng PW
J Biomed Sci; 2005 Dec; 12(6):999-1011. PubMed ID: 16228292
[TBL] [Abstract][Full Text] [Related]
14. Selective induction of apoptosis through the FADD/caspase-8 pathway by a p53 c-terminal peptide in human pre-malignant and malignant cells.
Li Y; Mao Y; Rosal RV; Dinnen RD; Williams AC; Brandt-Rauf PW; Fine RL
Int J Cancer; 2005 May; 115(1):55-64. PubMed ID: 15645452
[TBL] [Abstract][Full Text] [Related]
15. Two peptides derived from ras-p21 induce either phenotypic reversion or tumor cell necrosis of ras-transformed human cancer cells.
Adler V; Bowne W; Kamran I; Michl J; Friedman FK; Chin E; Zenilman M; Pincus MR
Cancer Chemother Pharmacol; 2008 Aug; 62(3):491-8. PubMed ID: 18066549
[TBL] [Abstract][Full Text] [Related]
16. NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells.
Rosal R; Pincus MR; Brandt-Rauf PW; Fine RL; Michl J; Wang H
Biochemistry; 2004 Feb; 43(7):1854-61. PubMed ID: 14967026
[TBL] [Abstract][Full Text] [Related]
17. Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway.
Ferreira AK; Meneguelo R; Pereira A; Filho OM; Chierice GO; Maria DA
Biomed Pharmacother; 2013 Jul; 67(6):481-7. PubMed ID: 23773853
[TBL] [Abstract][Full Text] [Related]
18. Tumor apoptosis induced by epoxide-containing piperazines, a new class of anti-cancer agents.
Eilon GF; Gu J; Slater LM; Hara K; Jacobs JW
Cancer Chemother Pharmacol; 2000; 45(3):183-91. PubMed ID: 10663635
[TBL] [Abstract][Full Text] [Related]
19. Sigma-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines.
Crawford KW; Bowen WD
Cancer Res; 2002 Jan; 62(1):313-22. PubMed ID: 11782394
[TBL] [Abstract][Full Text] [Related]
20. Nanosecond pulsed electric fields (nsPEF) induce direct electric field effects and biological effects on human colon carcinoma cells.
Hall EH; Schoenbach KH; Beebe SJ
DNA Cell Biol; 2005 May; 24(5):283-91. PubMed ID: 15869405
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]