381 related articles for article (PubMed ID: 20186123)
1. The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.
Pedrotti S; Bielli P; Paronetto MP; Ciccosanti F; Fimia GM; Stamm S; Manley JL; Sette C
EMBO J; 2010 Apr; 29(7):1235-47. PubMed ID: 20186123
[TBL] [Abstract][Full Text] [Related]
2. SAM68 is a physiological regulator of SMN2 splicing in spinal muscular atrophy.
Pagliarini V; Pelosi L; Bustamante MB; Nobili A; Berardinelli MG; D'Amelio M; Musarò A; Sette C
J Cell Biol; 2015 Oct; 211(1):77-90. PubMed ID: 26438828
[TBL] [Abstract][Full Text] [Related]
3. Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Nadal M; Anton R; Dorca-Arévalo J; Estébanez-Perpiñá E; Tizzano EF; Fuentes-Prior P
Protein Sci; 2023 Apr; 32(4):e4553. PubMed ID: 36560896
[TBL] [Abstract][Full Text] [Related]
4. Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.
Cartegni L; Hastings ML; Calarco JA; de Stanchina E; Krainer AR
Am J Hum Genet; 2006 Jan; 78(1):63-77. PubMed ID: 16385450
[TBL] [Abstract][Full Text] [Related]
5. Spinal muscular atrophy: a new player joins the battle for SMN2 exon 7 splicing.
Pedrotti S; Sette C
Cell Cycle; 2010 Oct; 9(19):3874-9. PubMed ID: 20890126
[TBL] [Abstract][Full Text] [Related]
6. hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing.
Kashima T; Rao N; David CJ; Manley JL
Hum Mol Genet; 2007 Dec; 16(24):3149-59. PubMed ID: 17884807
[TBL] [Abstract][Full Text] [Related]
7. Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model.
Bebee TW; Dominguez CE; Samadzadeh-Tarighat S; Akehurst KL; Chandler DS
Hum Mol Genet; 2012 Oct; 21(19):4301-13. PubMed ID: 22763238
[TBL] [Abstract][Full Text] [Related]
8. A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy.
Kashima T; Manley JL
Nat Genet; 2003 Aug; 34(4):460-3. PubMed ID: 12833158
[TBL] [Abstract][Full Text] [Related]
9. hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1.
Hofmann Y; Wirth B
Hum Mol Genet; 2002 Aug; 11(17):2037-49. PubMed ID: 12165565
[TBL] [Abstract][Full Text] [Related]
10. Extracellular pH change modulates the exon 7 splicing in SMN2 mRNA.
Chen YC; Yuo CY; Yang WK; Jong YJ; Lin HH; Chang YS; Chang JG
Mol Cell Neurosci; 2008 Oct; 39(2):268-72. PubMed ID: 18672065
[TBL] [Abstract][Full Text] [Related]
11. Securinine enhances SMN2 exon 7 inclusion in spinal muscular atrophy cells.
Chen YC; Chang JG; Liu TY; Jong YJ; Cheng WL; Yuo CY
Biomed Pharmacother; 2017 Apr; 88():708-714. PubMed ID: 28152480
[TBL] [Abstract][Full Text] [Related]
12. An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy.
Singh NN; Androphy EJ; Singh RN
Biochem Biophys Res Commun; 2004 Mar; 315(2):381-8. PubMed ID: 14766219
[TBL] [Abstract][Full Text] [Related]
13. hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7.
Cho S; Moon H; Loh TJ; Oh HK; Cho S; Choy HE; Song WK; Chun JS; Zheng X; Shen H
Biochim Biophys Acta; 2014; 1839(4):306-15. PubMed ID: 24533984
[TBL] [Abstract][Full Text] [Related]
14. SMN transcript stability: could modulation of messenger RNA degradation provide a novel therapy for spinal muscular atrophy?
Heier CR; Gogliotti RG; DiDonato CJ
J Child Neurol; 2007 Aug; 22(8):1013-8. PubMed ID: 17761657
[TBL] [Abstract][Full Text] [Related]
15. Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron.
Singh NK; Singh NN; Androphy EJ; Singh RN
Mol Cell Biol; 2006 Feb; 26(4):1333-46. PubMed ID: 16449646
[TBL] [Abstract][Full Text] [Related]
16. A rare SMN2 variant in a previously unrecognized composite splicing regulatory element induces exon 7 inclusion and reduces the clinical severity of spinal muscular atrophy.
Vezain M; Saugier-Veber P; Goina E; Touraine R; Manel V; Toutain A; Fehrenbach S; Frébourg T; Pagani F; Tosi M; Martins A
Hum Mutat; 2010 Jan; 31(1):E1110-25. PubMed ID: 19953646
[TBL] [Abstract][Full Text] [Related]
17. A negatively acting bifunctional RNA increases survival motor neuron both in vitro and in vivo.
Dickson A; Osman E; Lorson CL
Hum Gene Ther; 2008 Nov; 19(11):1307-15. PubMed ID: 19848583
[TBL] [Abstract][Full Text] [Related]
18. Evolving concepts on human SMN pre-mRNA splicing.
Singh RN
RNA Biol; 2007; 4(1):7-10. PubMed ID: 17592254
[TBL] [Abstract][Full Text] [Related]
19. An intronic element contributes to splicing repression in spinal muscular atrophy.
Kashima T; Rao N; Manley JL
Proc Natl Acad Sci U S A; 2007 Feb; 104(9):3426-31. PubMed ID: 17307868
[TBL] [Abstract][Full Text] [Related]
20. The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x.
Paronetto MP; Achsel T; Massiello A; Chalfant CE; Sette C
J Cell Biol; 2007 Mar; 176(7):929-39. PubMed ID: 17371836
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
