BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 20194896)

  • 1. The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.
    Bursen A; Schwabe K; Rüster B; Henschler R; Ruthardt M; Dingermann T; Marschalek R
    Blood; 2010 Apr; 115(17):3570-9. PubMed ID: 20194896
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The heterodimerization domains of MLL-FYRN and FYRC--are potential target structures in t(4;11) leukemia.
    Pless B; Oehm C; Knauer S; Stauber RH; Dingermann T; Marschalek R
    Leukemia; 2011 Apr; 25(4):663-70. PubMed ID: 21233834
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clinical significance of MLL-AF4 fusion transcript expression in the absence of a cytogenetically detectable t(4;11)(q21;q23) chromosomal translocation.
    Uckun FM; Herman-Hatten K; Crotty ML; Sensel MG; Sather HN; Tuel-Ahlgren L; Sarquis MB; Bostrom B; Nachman JB; Steinherz PG; Gaynon PS; Heerema N
    Blood; 1998 Aug; 92(3):810-21. PubMed ID: 9680349
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The mixed lineage leukemia (MLL) fusion-associated gene AF4 promotes CD133 transcription.
    Mak AB; Nixon AM; Moffat J
    Cancer Res; 2012 Apr; 72(8):1929-34. PubMed ID: 22337994
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited.
    Gué M; Sun JS; Boudier T
    BMC Cancer; 2006 Jan; 6():20. PubMed ID: 16433901
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia.
    Montes R; Ayllón V; Gutierrez-Aranda I; Prat I; Hernández-Lamas MC; Ponce L; Bresolin S; Te Kronnie G; Greaves M; Bueno C; Menendez P
    Blood; 2011 May; 117(18):4746-58. PubMed ID: 21389315
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.
    Thomas M; Gessner A; Vornlocher HP; Hadwiger P; Greil J; Heidenreich O
    Blood; 2005 Nov; 106(10):3559-66. PubMed ID: 16046533
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.
    Gessner A; Thomas M; Castro PG; Büchler L; Scholz A; Brümmendorf TH; Soria NM; Vormoor J; Greil J; Heidenreich O
    Leukemia; 2010 Oct; 24(10):1751-9. PubMed ID: 20686504
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
    Biswas D; Milne TA; Basrur V; Kim J; Elenitoba-Johnson KS; Allis CD; Roeder RG
    Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15751-6. PubMed ID: 21896721
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gene expression profiling of adult t(4;11)(q21;q23)-associated acute lymphoblastic leukemia reveals a different signature from pediatric cases.
    De Braekeleer E; Douet-Guilbert N; Le Bris MJ; Basinko A; Morel F; De Braekeleer M
    Anticancer Res; 2012 Sep; 32(9):3893-9. PubMed ID: 22993334
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology?
    Bursen A; Moritz S; Gaussmann A; Moritz S; Dingermann T; Marschalek R
    Oncogene; 2004 Aug; 23(37):6237-49. PubMed ID: 15221006
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AF4 encodes a ubiquitous protein that in both native and MLL-AF4 fusion types localizes to subnuclear compartments.
    Li Q; Frestedt JL; Kersey JH
    Blood; 1998 Nov; 92(10):3841-7. PubMed ID: 9808577
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular characterization of a rare MLL-AF4 (MLL-AFF1) fusion rearrangement in infant leukemia.
    Bizarro S; Cerveira N; Correia C; Lisboa S; Peixoto A; Norton L; Teixeira MR
    Cancer Genet Cytogenet; 2007 Oct; 178(1):61-4. PubMed ID: 17889710
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pro-B-cell to pre-B-cell development in B-lineage acute lymphoblastic leukemia expressing the MLL/AF4 fusion protein.
    Bertrand FE; Vogtenhuber C; Shah N; LeBien TW
    Blood; 2001 Dec; 98(12):3398-405. PubMed ID: 11719380
    [TBL] [Abstract][Full Text] [Related]  

  • 15. t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL.
    Kumar AR; Yao Q; Li Q; Sam TA; Kersey JH
    Leuk Res; 2011 Mar; 35(3):305-9. PubMed ID: 20869771
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cryptic t(4;11) encoding MLL-AF4 due to insertion of 5' MLL sequences in chromosome 4.
    von Bergh A; Gargallo P; De Prijck B; Vranckx H; Marschalek R; Larripa I; Kluin P; Schuuring E; Hagemeijer A
    Leukemia; 2001 Apr; 15(4):595-600. PubMed ID: 11368362
    [TBL] [Abstract][Full Text] [Related]  

  • 17. LAF4, an AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia.
    von Bergh AR; Beverloo HB; Rombout P; van Wering ER; van Weel MH; Beverstock GC; Kluin PM; Slater RM; Schuuring E
    Genes Chromosomes Cancer; 2002 Sep; 35(1):92-6. PubMed ID: 12203795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Authors' comments: t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL.
    Kumar AR; Yao Q; Li Q; Sam TA; Kersey JH
    Leuk Res; 2011 May; 35(5):697. PubMed ID: 21277021
    [No Abstract]   [Full Text] [Related]  

  • 19. A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program.
    Rice S; Jackson T; Crump NT; Fordham N; Elliott N; O'Byrne S; Fanego MDML; Addy D; Crabb T; Dryden C; Inglott S; Ladon D; Wright G; Bartram J; Ancliff P; Mead AJ; Halsey C; Roberts I; Milne TA; Roy A
    Nat Commun; 2021 Nov; 12(1):6905. PubMed ID: 34824279
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cryptic splice site activation during RNA processing of MLL/AF4 chimeric transcripts in infants with t(4;11) positive ALL.
    Divoky V; Trka JM; Watzinger F; Lion T
    Gene; 2000 Apr; 247(1-2):111-8. PubMed ID: 10773450
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.