These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 20197543)

  • 1. Allosteric protein kinase regulation by pseudokinases: insights from STRAD.
    Rajakulendran T; Sicheri F
    Sci Signal; 2010 Mar; 3(111):pe8. PubMed ID: 20197543
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation.
    Zeqiraj E; Filippi BM; Deak M; Alessi DR; van Aalten DM
    Science; 2009 Dec; 326(5960):1707-11. PubMed ID: 19892943
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor.
    Zeqiraj E; Filippi BM; Goldie S; Navratilova I; Boudeau J; Deak M; Alessi DR; van Aalten DM
    PLoS Biol; 2009 Jun; 7(6):e1000126. PubMed ID: 19513107
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.
    Hawley SA; Boudeau J; Reid JL; Mustard KJ; Udd L; Mäkelä TP; Alessi DR; Hardie DG
    J Biol; 2003; 2(4):28. PubMed ID: 14511394
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of the LKB1-STRAD-MO25 complex.
    Boudeau J; Scott JW; Resta N; Deak M; Kieloch A; Komander D; Hardie DG; Prescott AR; van Aalten DM; Alessi DR
    J Cell Sci; 2004 Dec; 117(Pt 26):6365-75. PubMed ID: 15561763
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD.
    Baas AF; Boudeau J; Sapkota GP; Smit L; Medema R; Morrice NA; Alessi DR; Clevers HC
    EMBO J; 2003 Jun; 22(12):3062-72. PubMed ID: 12805220
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emerging roles of pseudokinases.
    Boudeau J; Miranda-Saavedra D; Barton GJ; Alessi DR
    Trends Cell Biol; 2006 Sep; 16(9):443-52. PubMed ID: 16879967
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of 3-phosphoglycerate and other metabolites on the activation of AMP-activated protein kinase by LKB1-STRAD-MO25.
    Ellingson WJ; Chesser DG; Winder WW
    Am J Physiol Endocrinol Metab; 2007 Feb; 292(2):E400-7. PubMed ID: 16985256
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of the liver kinase B1-mouse protein-25 -Ste-20-related adaptor protein complex in adult mouse skeletal muscle.
    Smith CD; Compton RA; Bowler JS; Kemp JT; Sudweeks SN; Thomson DM; Winder WW
    J Appl Physiol (1985); 2011 Dec; 111(6):1622-8. PubMed ID: 21903876
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methods to assess small molecule allosteric modulators of the STRAD pseudokinase.
    Qing T; Liu J; Liu F; Mitchell DC; Beresis RT; Gordan JD
    Methods Enzymol; 2022; 667():427-453. PubMed ID: 35525550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural insights into regulatory mechanisms of MO25-mediated kinase activation.
    Hao Q; Feng M; Shi Z; Li C; Chen M; Wang W; Zhang M; Jiao S; Zhou Z
    J Struct Biol; 2014 May; 186(2):224-33. PubMed ID: 24746913
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into the structural dynamics of Liver kinase B1 (LKB1) by the binding of STe20 Related Adapterα (STRADα) and Mouse protein 25α (MO25α) co-activators.
    Rungsung I; Ramaswamy A
    J Biomol Struct Dyn; 2017 Apr; 35(5):1138-1152. PubMed ID: 27160967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. STRAD pseudokinases regulate axogenesis and LKB1 stability.
    Veleva-Rotse BO; Smart JL; Baas AF; Edmonds B; Zhao ZM; Brown A; Klug LR; Hansen K; Reilly G; Gardner AP; Subbiah K; Gaucher EA; Clevers H; Barnes AP
    Neural Dev; 2014 Mar; 9():5. PubMed ID: 24594058
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex.
    ten Klooster JP; Jansen M; Yuan J; Oorschot V; Begthel H; Di Giacomo V; Colland F; de Koning J; Maurice MM; Hornbeck P; Clevers H
    Dev Cell; 2009 Apr; 16(4):551-62. PubMed ID: 19386264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of LKB1/STRAD localization and function by E-cadherin.
    Sebbagh M; Santoni MJ; Hall B; Borg JP; Schwartz MA
    Curr Biol; 2009 Jan; 19(1):37-42. PubMed ID: 19110428
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.
    Boudeau J; Baas AF; Deak M; Morrice NA; Kieloch A; Schutkowski M; Prescott AR; Clevers HC; Alessi DR
    EMBO J; 2003 Oct; 22(19):5102-14. PubMed ID: 14517248
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genome-wide and structural analyses of pseudokinases encoded in the genome of Arabidopsis thaliana provide functional insights.
    Paul A; Srinivasan N
    Proteins; 2020 Dec; 88(12):1620-1638. PubMed ID: 32667690
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural insights into the activation of MST3 by MO25.
    Mehellou Y; Alessi DR; Macartney TJ; Szklarz M; Knapp S; Elkins JM
    Biochem Biophys Res Commun; 2013 Feb; 431(3):604-9. PubMed ID: 23296203
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dimerization-induced allostery in protein kinase regulation.
    Lavoie H; Li JJ; Thevakumaran N; Therrien M; Sicheri F
    Trends Biochem Sci; 2014 Oct; 39(10):475-86. PubMed ID: 25220378
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of MO25 alpha in complex with the C terminus of the pseudo kinase STE20-related adaptor.
    Milburn CC; Boudeau J; Deak M; Alessi DR; van Aalten DM
    Nat Struct Mol Biol; 2004 Feb; 11(2):193-200. PubMed ID: 14730349
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.