BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1031 related articles for article (PubMed ID: 20203102)

  • 21. Mechanisms of high-glucose/insulin-mediated desensitization of acute insulin-stimulated glucose transport and Akt activation.
    Robinson KA; Buse MG
    Am J Physiol Endocrinol Metab; 2008 May; 294(5):E870-81. PubMed ID: 18303120
    [TBL] [Abstract][Full Text] [Related]  

  • 22. S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2.
    Zhang J; Gao Z; Yin J; Quon MJ; Ye J
    J Biol Chem; 2008 Dec; 283(51):35375-82. PubMed ID: 18952604
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1.
    Liu Y; Fanburg BL
    Am J Respir Cell Mol Biol; 2006 Feb; 34(2):182-91. PubMed ID: 16195541
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.
    Liu D; Bordicchia M; Zhang C; Fang H; Wei W; Li JL; Guilherme A; Guntur K; Czech MP; Collins S
    J Clin Invest; 2016 May; 126(5):1704-16. PubMed ID: 27018708
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Raptor and Rheb negatively regulate skeletal myogenesis through suppression of insulin receptor substrate 1 (IRS1).
    Ge Y; Yoon MS; Chen J
    J Biol Chem; 2011 Oct; 286(41):35675-35682. PubMed ID: 21852229
    [TBL] [Abstract][Full Text] [Related]  

  • 26. PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ.
    Kurebayashi Y; Nagai S; Ikejiri A; Ohtani M; Ichiyama K; Baba Y; Yamada T; Egami S; Hoshii T; Hirao A; Matsuda S; Koyasu S
    Cell Rep; 2012 Apr; 1(4):360-73. PubMed ID: 22832227
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.
    Suh JM; Song JH; Kim DW; Kim H; Chung HK; Hwang JH; Kim JM; Hwang ES; Chung J; Han JH; Cho BY; Ro HK; Shong M
    J Biol Chem; 2003 Jun; 278(24):21960-71. PubMed ID: 12668683
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport.
    Staubs PA; Nelson JG; Reichart DR; Olefsky JM
    J Biol Chem; 1998 Sep; 273(39):25139-47. PubMed ID: 9737973
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
    Andreozzi F; D'Alessandris C; Federici M; Laratta E; Del Guerra S; Del Prato S; Marchetti P; Lauro R; Perticone F; Sesti G
    Endocrinology; 2004 Jun; 145(6):2845-57. PubMed ID: 15001544
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR.
    Tzatsos A
    J Biol Chem; 2009 Aug; 284(34):22525-34. PubMed ID: 19561084
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
    Fang CX; Yang X; Sreejayan N; Ren J
    Exp Neurol; 2007 Jan; 203(1):196-204. PubMed ID: 16962100
    [TBL] [Abstract][Full Text] [Related]  

  • 32. EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.
    Arif A; Terenzi F; Potdar AA; Jia J; Sacks J; China A; Halawani D; Vasu K; Li X; Brown JM; Chen J; Kozma SC; Thomas G; Fox PL
    Nature; 2017 Feb; 542(7641):357-361. PubMed ID: 28178239
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
    Acosta-Jaquez HA; Keller JA; Foster KG; Ekim B; Soliman GA; Feener EP; Ballif BA; Fingar DC
    Mol Cell Biol; 2009 Aug; 29(15):4308-24. PubMed ID: 19487463
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Gingerenone A Sensitizes the Insulin Receptor and Increases Glucose Uptake by Inhibiting the Activity of p70 S6 Kinase.
    Chen J; Sun J; Prinz RA; Li Y; Xu X
    Mol Nutr Food Res; 2018 Dec; 62(23):e1800709. PubMed ID: 30296358
    [TBL] [Abstract][Full Text] [Related]  

  • 35. β-Arrestin signal complex plays a critical role in adipose differentiation.
    Santos-Zas I; Lodeiro M; Gurriarán-Rodríguez U; Bouzo-Lorenzo M; Mosteiro CS; Casanueva FF; Casabiell X; Pazos Y; Camiña JP
    Int J Biochem Cell Biol; 2013 Jul; 45(7):1281-92. PubMed ID: 23557604
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Central insulin signaling is attenuated by long-term insulin exposure via insulin receptor substrate-1 serine phosphorylation, proteasomal degradation, and lysosomal insulin receptor degradation.
    Mayer CM; Belsham DD
    Endocrinology; 2010 Jan; 151(1):75-84. PubMed ID: 19887566
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.
    Ginion A; Auquier J; Benton CR; Mouton C; Vanoverschelde JL; Hue L; Horman S; Beauloye C; Bertrand L
    Am J Physiol Heart Circ Physiol; 2011 Aug; 301(2):H469-77. PubMed ID: 21602475
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Improved insulin sensitivity by rapamycin is associated with reduction of mTOR and S6K1 activities in L6 myotubes.
    Hwang SL; Li X; Lee JY; Chang HW
    Biochem Biophys Res Commun; 2012 Feb; 418(2):402-7. PubMed ID: 22281494
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.
    Breuleux M; Klopfenstein M; Stephan C; Doughty CA; Barys L; Maira SM; Kwiatkowski D; Lane HA
    Mol Cancer Ther; 2009 Apr; 8(4):742-53. PubMed ID: 19372546
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue.
    Houde VP; Brûlé S; Festuccia WT; Blanchard PG; Bellmann K; Deshaies Y; Marette A
    Diabetes; 2010 Jun; 59(6):1338-48. PubMed ID: 20299475
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 52.