159 related articles for article (PubMed ID: 20217185)
1. 3D-Pharmacophore mapping of thymidine-based inhibitors of TMPK as potential antituberculosis agents.
Andrade CH; Pasqualoto KF; Ferreira EI; Hopfinger AJ
J Comput Aided Mol Des; 2010 Feb; 24(2):157-72. PubMed ID: 20217185
[TBL] [Abstract][Full Text] [Related]
2. Rational design and 3D-pharmacophore mapping of 5'-thiourea-substituted alpha-thymidine analogues as mycobacterial TMPK inhibitors.
Andrade CH; Pasqualoto KF; Ferreira EI; Hopfinger AJ
J Chem Inf Model; 2009 Apr; 49(4):1070-8. PubMed ID: 19296716
[TBL] [Abstract][Full Text] [Related]
3. 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
Aparna V; Jeevan J; Ravi M; Desiraju GR; Gopalakrishnan B
Bioorg Med Chem Lett; 2006 Feb; 16(4):1014-20. PubMed ID: 16290929
[TBL] [Abstract][Full Text] [Related]
4. Computer-assisted combinatorial design of bicyclic thymidine analogs as inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Frecer V; Seneci P; Miertus S
J Comput Aided Mol Des; 2011 Jan; 25(1):31-49. PubMed ID: 21082329
[TBL] [Abstract][Full Text] [Related]
5. Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Vanheusden V; Munier-Lehmann H; Froeyen M; Busson R; Rozenski J; Herdewijn P; Van Calenbergh S
J Med Chem; 2004 Dec; 47(25):6187-94. PubMed ID: 15566289
[TBL] [Abstract][Full Text] [Related]
6. Drug design and identification of potent leads against mycobacterium tuberculosis thymidine monophosphate kinase.
Van Calenbergh S; Pochet S; Munier-Lehmann H
Curr Top Med Chem; 2012; 12(7):694-705. PubMed ID: 22283813
[TBL] [Abstract][Full Text] [Related]
7. 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Vanheusden V; Munier-Lehmann H; Froeyen M; Dugué L; Heyerick A; De Keukeleire D; Pochet S; Busson R; Herdewijn P; Van Calenbergh S
J Med Chem; 2003 Aug; 46(18):3811-21. PubMed ID: 12930144
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors.
Toti KS; Verbeke F; Risseeuw MD; Frecer V; Munier-Lehmann H; Van Calenbergh S
Bioorg Med Chem; 2013 Jan; 21(1):257-68. PubMed ID: 23199481
[TBL] [Abstract][Full Text] [Related]
9. Structural and chemical basis for enhanced affinity to a series of mycobacterial thymidine monophosphate kinase inhibitors: fragment-based QSAR and QM/MM docking studies.
Bueno RV; Toledo NR; Neves BJ; Braga RC; Andrade CH
J Mol Model; 2013 Jan; 19(1):179-92. PubMed ID: 22846924
[TBL] [Abstract][Full Text] [Related]
10. Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Vanheusden V; Van Rompaey P; Munier-Lehmann H; Pochet S; Herdewijn P; Van Calenbergh S
Bioorg Med Chem Lett; 2003 Sep; 13(18):3045-8. PubMed ID: 12941330
[TBL] [Abstract][Full Text] [Related]
11. Structure-aided design of inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Van Calenbergh S
Verh K Acad Geneeskd Belg; 2006; 68(4):223-48. PubMed ID: 17214439
[TBL] [Abstract][Full Text] [Related]
12. Exploring acyclic nucleoside analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Familiar O; Munier-Lehmann H; Negri A; Gago F; Douguet D; Rigouts L; Hernández AI; Camarasa MJ; Pérez-Pérez MJ
ChemMedChem; 2008 Jul; 3(7):1083-93. PubMed ID: 18418833
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase.
Van Poecke S; Munier-Lehmann H; Helynck O; Froeyen M; Van Calenbergh S
Bioorg Med Chem; 2011 Dec; 19(24):7603-11. PubMed ID: 22061826
[TBL] [Abstract][Full Text] [Related]
14. Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.
Pochet S; Dugué L; Labesse G; Delepierre M; Munier-Lehmann H
Chembiochem; 2003 Aug; 4(8):742-7. PubMed ID: 12898625
[TBL] [Abstract][Full Text] [Related]
15. A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Gasse C; Huteau V; Douguet D; Munier-Lehmann H; Pochet S
Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):1057-61. PubMed ID: 18058536
[No Abstract] [Full Text] [Related]
16. Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
Van Daele I; Munier-Lehmann H; Froeyen M; Balzarini J; Van Calenbergh S
J Med Chem; 2007 Nov; 50(22):5281-92. PubMed ID: 17910427
[TBL] [Abstract][Full Text] [Related]
17. Pharmacophore optimization and design of competitive inhibitors of thymidine monophosphate kinase through molecular modeling studies.
Chitre TS; Kathiravan MK; Bothara KG; Bhandari SV; Jalnapurkar RR
Chem Biol Drug Des; 2011 Nov; 78(5):826-34. PubMed ID: 21801308
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of bicyclic nucleosides as inhibitors of M. tuberculosis thymidylate kinase.
Van Daele I; Munier-Lehmann H; Hendrickx PM; Marchal G; Chavarot P; Froeyen M; Qing L; Martins JC; Van Calenbergh S
ChemMedChem; 2006 Oct; 1(10):1081-90. PubMed ID: 16921580
[TBL] [Abstract][Full Text] [Related]
19. Knowledge based identification of potent antitubercular compounds using structure based virtual screening and structure interaction fingerprints.
Kumar A; Chaturvedi V; Bhatnagar S; Sinha S; Siddiqi MI
J Chem Inf Model; 2009 Jan; 49(1):35-42. PubMed ID: 19063713
[TBL] [Abstract][Full Text] [Related]
20. Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents.
Song L; Risseeuw MDP; Froeyen M; Karalic I; Goeman J; Cappoen D; Van der Eycken J; Cos P; Munier-Lehmann H; Van Calenbergh S
Bioorg Med Chem; 2016 Nov; 24(21):5172-5182. PubMed ID: 27614917
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]