261 related articles for article (PubMed ID: 20224574)
1. A divalent FHA/BRCT-binding mechanism couples the MRE11-RAD50-NBS1 complex to damaged chromatin.
Hari FJ; Spycher C; Jungmichel S; Pavic L; Stucki M
EMBO Rep; 2010 May; 11(5):387-92. PubMed ID: 20224574
[TBL] [Abstract][Full Text] [Related]
2. Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage.
Chapman JR; Jackson SP
EMBO Rep; 2008 Aug; 9(8):795-801. PubMed ID: 18583988
[TBL] [Abstract][Full Text] [Related]
3. Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin.
Spycher C; Miller ES; Townsend K; Pavic L; Morrice NA; Janscak P; Stewart GS; Stucki M
J Cell Biol; 2008 Apr; 181(2):227-40. PubMed ID: 18411308
[TBL] [Abstract][Full Text] [Related]
4. MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks.
Wu L; Luo K; Lou Z; Chen J
Proc Natl Acad Sci U S A; 2008 Aug; 105(32):11200-5. PubMed ID: 18678890
[TBL] [Abstract][Full Text] [Related]
5. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
6. Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites.
Xu C; Wu L; Cui G; Botuyan MV; Chen J; Mer G
J Mol Biol; 2008 Aug; 381(2):361-72. PubMed ID: 18582474
[TBL] [Abstract][Full Text] [Related]
7. Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.
Henrich SM; Usadel C; Werwein E; Burdova K; Janscak P; Ferrari S; Hess D; Klempnauer KH
Sci Rep; 2017 Jan; 7():41663. PubMed ID: 28128338
[TBL] [Abstract][Full Text] [Related]
8. Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Williams RS; Dodson GE; Limbo O; Yamada Y; Williams JS; Guenther G; Classen S; Glover JN; Iwasaki H; Russell P; Tainer JA
Cell; 2009 Oct; 139(1):87-99. PubMed ID: 19804755
[TBL] [Abstract][Full Text] [Related]
9. Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses.
Zhao S; Renthal W; Lee EY
Nucleic Acids Res; 2002 Nov; 30(22):4815-22. PubMed ID: 12433983
[TBL] [Abstract][Full Text] [Related]
10. MDC1 is required for the intra-S-phase DNA damage checkpoint.
Goldberg M; Stucki M; Falck J; D'Amours D; Rahman D; Pappin D; Bartek J; Jackson SP
Nature; 2003 Feb; 421(6926):952-6. PubMed ID: 12607003
[TBL] [Abstract][Full Text] [Related]
11. Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention.
Lukas C; Melander F; Stucki M; Falck J; Bekker-Jensen S; Goldberg M; Lerenthal Y; Jackson SP; Bartek J; Lukas J
EMBO J; 2004 Jul; 23(13):2674-83. PubMed ID: 15201865
[TBL] [Abstract][Full Text] [Related]
12. The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.
Lee AY; Liu E; Wu X
J Biol Chem; 2007 Nov; 282(44):32243-55. PubMed ID: 17715134
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin.
Melander F; Bekker-Jensen S; Falck J; Bartek J; Mailand N; Lukas J
J Cell Biol; 2008 Apr; 181(2):213-26. PubMed ID: 18411307
[TBL] [Abstract][Full Text] [Related]
14. Molecular mechanism of the recruitment of NBS1/hMRE11/hRAD50 complex to DNA double-strand breaks: NBS1 binds to gamma-H2AX through FHA/BRCT domain.
Kobayashi J
J Radiat Res; 2004 Dec; 45(4):473-8. PubMed ID: 15635255
[TBL] [Abstract][Full Text] [Related]
15. The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity.
Mirzoeva OK; Kawaguchi T; Pieper RO
Mol Cancer Ther; 2006 Nov; 5(11):2757-66. PubMed ID: 17121922
[TBL] [Abstract][Full Text] [Related]
16. NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation.
Anand R; Jasrotia A; Bundschuh D; Howard SM; Ranjha L; Stucki M; Cejka P
EMBO J; 2019 Apr; 38(7):. PubMed ID: 30787182
[TBL] [Abstract][Full Text] [Related]
17. MDC1 is a mediator of the mammalian DNA damage checkpoint.
Stewart GS; Wang B; Bignell CR; Taylor AM; Elledge SJ
Nature; 2003 Feb; 421(6926):961-6. PubMed ID: 12607005
[TBL] [Abstract][Full Text] [Related]
18. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein.
Zhou H; Kawamura K; Yanagihara H; Kobayashi J; Zhang-Akiyama QM
J Radiat Res; 2017 Jul; 58(4):487-494. PubMed ID: 28369484
[TBL] [Abstract][Full Text] [Related]
19. Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation.
Cerosaletti KM; Concannon P
J Biol Chem; 2003 Jun; 278(24):21944-51. PubMed ID: 12679336
[TBL] [Abstract][Full Text] [Related]
20. Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.
Wang Q; Goldstein M; Alexander P; Wakeman TP; Sun T; Feng J; Lou Z; Kastan MB; Wang XF
EMBO J; 2014 Apr; 33(8):862-77. PubMed ID: 24534091
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
