168 related articles for article (PubMed ID: 20225862)
1. Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.
Jourdan F; Leese MP; Dohle W; Hamel E; Ferrandis E; Newman SP; Purohit A; Reed MJ; Potter BV
J Med Chem; 2010 Apr; 53(7):2942-51. PubMed ID: 20225862
[TBL] [Abstract][Full Text] [Related]
2. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
Leese MP; Leblond B; Smith A; Newman SP; Di Fiore A; De Simone G; Supuran CT; Purohit A; Reed MJ; Potter BV
J Med Chem; 2006 Dec; 49(26):7683-96. PubMed ID: 17181151
[TBL] [Abstract][Full Text] [Related]
3. Structure-activity relationships of C-17-substituted estratriene-3-O-sulfamates as anticancer agents.
Jourdan F; Leese MP; Dohle W; Ferrandis E; Newman SP; Chander S; Purohit A; Potter BV
J Med Chem; 2011 Jul; 54(13):4863-79. PubMed ID: 21604672
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, antiproliferative activity and inhibition of tubulin polymerization by anthracenone-based oxime derivatives.
Surkau G; Böhm KJ; Müller K; Prinz H
Eur J Med Chem; 2010 Aug; 45(8):3354-64. PubMed ID: 20546980
[TBL] [Abstract][Full Text] [Related]
5. Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
Edsall AB; Mohanakrishnan AK; Yang D; Fanwick PE; Hamel E; Hanson AD; Agoston GE; Cushman M
J Med Chem; 2004 Oct; 47(21):5126-39. PubMed ID: 15456256
[TBL] [Abstract][Full Text] [Related]
6. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
Leese MP; Jourdan FL; Gaukroger K; Mahon MF; Newman SP; Foster PA; Stengel C; Regis-Lydi S; Ferrandis E; Di Fiore A; De Simone G; Supuran CT; Purohit A; Reed MJ; Potter BV
J Med Chem; 2008 Mar; 51(5):1295-308. PubMed ID: 18260615
[TBL] [Abstract][Full Text] [Related]
7. 3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.
Bubert C; Leese MP; Mahon MF; Ferrandis E; Regis-Lydi S; Kasprzyk PG; Newman SP; Ho YT; Purohit A; Reed MJ; Potter BV
J Med Chem; 2007 Sep; 50(18):4431-43. PubMed ID: 17696419
[TBL] [Abstract][Full Text] [Related]
8. Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling.
Jourdan F; Bubert C; Leese MP; Smith A; Ferrandis E; Regis-Lydi S; Newman SP; Purohit A; Reed MJ; Potter BV
Org Biomol Chem; 2008 Nov; 6(22):4108-19. PubMed ID: 18972041
[TBL] [Abstract][Full Text] [Related]
9. A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
Leese MP; Hejaz HA; Mahon MF; Newman SP; Purohit A; Reed MJ; Potter BV
J Med Chem; 2005 Aug; 48(16):5243-56. PubMed ID: 16078843
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
[TBL] [Abstract][Full Text] [Related]
11. Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure.
Dohle W; Jourdan FL; Menchon G; Prota AE; Foster PA; Mannion P; Hamel E; Thomas MP; Kasprzyk PG; Ferrandis E; Steinmetz MO; Leese MP; Potter BVL
J Med Chem; 2018 Feb; 61(3):1031-1044. PubMed ID: 29227648
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity profiles of A-homoestranes, the estratropones.
Miller TA; Bulman AL; Thompson CD; Garst ME; Macdonald TL
J Med Chem; 1997 Nov; 40(23):3836-41. PubMed ID: 9371249
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety.
Nickel HC; Schmidt P; Böhm KJ; Baasner S; Müller K; Gerlach M; Unger E; Günther EG; Prinz H
Eur J Med Chem; 2010 Aug; 45(8):3420-38. PubMed ID: 20537765
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of 2-substituted 17β-hydroxy/17-methylene estratrienes and their in vitro cytotoxicity in human cancer cell cultures.
Panchapakesan G; Dhayalan V; Dhatchana Moorthy N; Saranya N; Mohanakrishnan AK
Steroids; 2011 Dec; 76(13):1491-504. PubMed ID: 21872616
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Sarkar T; Hamel E
Bioorg Med Chem; 2008 May; 16(10):5367-76. PubMed ID: 18440234
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and SAR of C12-C13-oxazoline derivatives of epothilone A.
Pfeiffer B; Hauenstein K; Merz P; Gertsch J; Altmann KH
Bioorg Med Chem Lett; 2009 Jul; 19(14):3760-3. PubMed ID: 19433359
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, cytotoxic effects and tubulin polymerization inhibition of 1,4-disubstituted 1,2,3-triazole analogs of 2-methoxyestradiol.
Solum EJ; Vik A; Hansen TV
Steroids; 2014 Sep; 87():46-53. PubMed ID: 24923521
[TBL] [Abstract][Full Text] [Related]
18. Exploring the effect of 2,3,4-trimethoxy-phenyl moiety as a component of indolephenstatins.
Alvarez C; Alvarez R; Corchete P; Pérez-Melero C; Peláez R; Medarde M
Eur J Med Chem; 2010 Feb; 45(2):588-97. PubMed ID: 19939521
[TBL] [Abstract][Full Text] [Related]
19. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
J Med Chem; 2007 Sep; 50(18):4548-52. PubMed ID: 17685504
[TBL] [Abstract][Full Text] [Related]
20. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
Chiang YK; Kuo CC; Wu YS; Chen CT; Coumar MS; Wu JS; Hsieh HP; Chang CY; Jseng HY; Wu MH; Leou JS; Song JS; Chang JY; Lyu PC; Chao YS; Wu SY
J Med Chem; 2009 Jul; 52(14):4221-33. PubMed ID: 19507860
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
