BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

348 related articles for article (PubMed ID: 20228232)

  • 1. A comparison of whole genome gene expression profiles of HepaRG cells and HepG2 cells to primary human hepatocytes and human liver tissues.
    Hart SN; Li Y; Nakamoto K; Subileau EA; Steen D; Zhong XB
    Drug Metab Dispos; 2010 Jun; 38(6):988-94. PubMed ID: 20228232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes.
    Jetten MJ; Kleinjans JC; Claessen SM; Chesné C; van Delft JH
    Toxicol In Vitro; 2013 Oct; 27(7):2031-40. PubMed ID: 23911569
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures.
    Yokoyama Y; Sasaki Y; Terasaki N; Kawataki T; Takekawa K; Iwase Y; Shimizu T; Sanoh S; Ohta S
    Biol Pharm Bull; 2018 May; 41(5):722-732. PubMed ID: 29445054
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
    Aninat C; Piton A; Glaise D; Le Charpentier T; Langouët S; Morel F; Guguen-Guillouzo C; Guillouzo A
    Drug Metab Dispos; 2006 Jan; 34(1):75-83. PubMed ID: 16204462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.
    Guillouzo A; Corlu A; Aninat C; Glaise D; Morel F; Guguen-Guillouzo C
    Chem Biol Interact; 2007 May; 168(1):66-73. PubMed ID: 17241619
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line.
    Le Vee M; Jigorel E; Glaise D; Gripon P; Guguen-Guillouzo C; Fardel O
    Eur J Pharm Sci; 2006 May; 28(1-2):109-17. PubMed ID: 16488578
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative analysis of 3D culture methods on human HepG2 cells.
    Luckert C; Schulz C; Lehmann N; Thomas M; Hofmann U; Hammad S; Hengstler JG; Braeuning A; Lampen A; Hessel S
    Arch Toxicol; 2017 Jan; 91(1):393-406. PubMed ID: 26872951
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues.
    Olsavsky KM; Page JL; Johnson MC; Zarbl H; Strom SC; Omiecinski CJ
    Toxicol Appl Pharmacol; 2007 Jul; 222(1):42-56. PubMed ID: 17512962
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.
    Schulz C; Kammerer S; Küpper JH
    Clin Hemorheol Microcirc; 2019; 73(1):249-260. PubMed ID: 31561354
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human Hepatic HepaRG Cells Maintain an Organotypic Phenotype with High Intrinsic CYP450 Activity/Metabolism and Significantly Outperform Standard HepG2/C3A Cells for Pharmaceutical and Therapeutic Applications.
    Nelson LJ; Morgan K; Treskes P; Samuel K; Henderson CJ; LeBled C; Homer N; Grant MH; Hayes PC; Plevris JN
    Basic Clin Pharmacol Toxicol; 2017 Jan; 120(1):30-37. PubMed ID: 27285124
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification.
    Jennen DG; Magkoufopoulou C; Ketelslegers HB; van Herwijnen MH; Kleinjans JC; van Delft JH
    Toxicol Sci; 2010 May; 115(1):66-79. PubMed ID: 20106945
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor.
    Cerec V; Glaise D; Garnier D; Morosan S; Turlin B; Drenou B; Gripon P; Kremsdorf D; Guguen-Guillouzo C; Corlu A
    Hepatology; 2007 Apr; 45(4):957-67. PubMed ID: 17393521
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-α.
    Al-Attrache H; Sharanek A; Burban A; Burbank M; Gicquel T; Abdel-Razzak Z; Guguen-Guillouzo C; Morel I; Guillouzo A
    Toxicol Lett; 2016 Sep; 258():71-86. PubMed ID: 27313093
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems.
    Rodrigues RM; Heymans A; De Boe V; Sachinidis A; Chaudhari U; Govaere O; Roskams T; Vanhaecke T; Rogiers V; De Kock J
    Toxicol Lett; 2016 Jan; 240(1):50-9. PubMed ID: 26497421
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human hepatoma HepaRG cell line engraftment in severe combined immunodeficient × beige mice using mouse-specific anti-Fas antibody.
    Jiang L; Li JG; Lan L; Wang YM; Mao Q; You JP
    Transplant Proc; 2010 Nov; 42(9):3773-8. PubMed ID: 21094855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro.
    Lübberstedt M; Müller-Vieira U; Mayer M; Biemel KM; Knöspel F; Knobeloch D; Nüssler AK; Gerlach JC; Zeilinger K
    J Pharmacol Toxicol Methods; 2011; 63(1):59-68. PubMed ID: 20460162
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Establishment of a Drug-Induced, Bile Acid-Dependent Hepatotoxicity Model Using HepaRG Cells.
    Susukida T; Sekine S; Nozaki M; Tokizono M; Oizumi K; Horie T; Ito K
    J Pharm Sci; 2016 Apr; 105(4):1550-60. PubMed ID: 26952880
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A systematic comparison of the impact of inflammatory signaling on absorption, distribution, metabolism, and excretion gene expression and activity in primary human hepatocytes and HepaRG cells.
    Klein M; Thomas M; Hofmann U; Seehofer D; Damm G; Zanger UM
    Drug Metab Dispos; 2015 Feb; 43(2):273-83. PubMed ID: 25480923
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of HepaRG cells following growth in proliferative and differentiated culture conditions reveals distinct bioenergetic profiles.
    Young CKJ; Young MJ
    Cell Cycle; 2019 Feb; 18(4):476-499. PubMed ID: 30755072
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes.
    Woolbright BL; McGill MR; Yan H; Jaeschke H
    Basic Clin Pharmacol Toxicol; 2016 Feb; 118(2):160-7. PubMed ID: 26176423
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.