194 related articles for article (PubMed ID: 20229566)
21. MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity.
Yang W; Guastella J; Huang JC; Wang Y; Zhang L; Xue D; Tran M; Woodward R; Kasibhatla S; Tseng B; Drewe J; Cai SX
Br J Pharmacol; 2003 Sep; 140(2):402-12. PubMed ID: 12970077
[TBL] [Abstract][Full Text] [Related]
22. A comparative study of warheads for design of cysteine protease inhibitors.
Silva DG; Ribeiro JFR; De Vita D; Cianni L; Franco CH; Freitas-Junior LH; Moraes CB; Rocha JR; Burtoloso ACB; Kenny PW; Leitão A; Montanari CA
Bioorg Med Chem Lett; 2017 Nov; 27(22):5031-5035. PubMed ID: 29054358
[TBL] [Abstract][Full Text] [Related]
23. 2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design.
Giroud M; Kuhn B; Saint-Auret S; Kuratli C; Martin RE; Schuler F; Diederich F; Kaiser M; Brun R; Schirmeister T; Haap W
J Med Chem; 2018 Apr; 61(8):3370-3388. PubMed ID: 29590751
[TBL] [Abstract][Full Text] [Related]
24. Potent and selective nonpeptide inhibitors of caspases 3 and 7.
Lee D; Long SA; Murray JH; Adams JL; Nuttall ME; Nadeau DP; Kikly K; Winkler JD; Sung CM; Ryan MD; Levy MA; Keller PM; DeWolf WE
J Med Chem; 2001 Jun; 44(12):2015-26. PubMed ID: 11384246
[TBL] [Abstract][Full Text] [Related]
25. Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1beta production.
Ravizza T; Noé F; Zardoni D; Vaghi V; Sifringer M; Vezzani A
Neurobiol Dis; 2008 Sep; 31(3):327-33. PubMed ID: 18632279
[TBL] [Abstract][Full Text] [Related]
26. Caspase-1 inhibition mediates neuroprotection in experimental stroke by polarizing M2 microglia/macrophage and suppressing NF-κB activation.
Li Q; Dai Z; Cao Y; Wang L
Biochem Biophys Res Commun; 2019 May; 513(2):479-485. PubMed ID: 30979498
[TBL] [Abstract][Full Text] [Related]
27. Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei.
Schirmeister T; Schmitz J; Jung S; Schmenger T; Krauth-Siegel RL; Gütschow M
Bioorg Med Chem Lett; 2017 Jan; 27(1):45-50. PubMed ID: 27890381
[TBL] [Abstract][Full Text] [Related]
28. Highly selective azadipeptide nitrile inhibitors for cathepsin K: design, synthesis and activity assays.
Ren XF; Li HW; Fang X; Wu Y; Wang L; Zou S
Org Biomol Chem; 2013 Feb; 11(7):1143-8. PubMed ID: 23299878
[TBL] [Abstract][Full Text] [Related]
29. Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors.
Ettari R; Micale N; Schirmeister T; Gelhaus C; Leippe M; Nizi E; Di Francesco ME; Grasso S; Zappalà M
J Med Chem; 2009 Apr; 52(7):2157-60. PubMed ID: 19296600
[TBL] [Abstract][Full Text] [Related]
30. Caspase inhibitors: a pharmaceutical industry perspective.
Linton SD
Curr Top Med Chem; 2005; 5(16):1697-717. PubMed ID: 16375749
[TBL] [Abstract][Full Text] [Related]
31. Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.
Yang PY; Wang M; Li L; Wu H; He CY; Yao SQ
Chemistry; 2012 May; 18(21):6528-41. PubMed ID: 22488888
[TBL] [Abstract][Full Text] [Related]
32. Organic azide inhibitors of cysteine proteases.
Le GT; Abbenante G; Madala PK; Hoang HN; Fairlie DP
J Am Chem Soc; 2006 Sep; 128(38):12396-7. PubMed ID: 16984172
[TBL] [Abstract][Full Text] [Related]
33. Rapid optimization of an ICE inhibitor synthesis using multiple reaction conditions in a parallel array.
Warmus JS; Ryder TR; Hodges JC; Kennedy RM; Brady KD
Bioorg Med Chem Lett; 1998 Sep; 8(17):2309-14. PubMed ID: 9873533
[TBL] [Abstract][Full Text] [Related]
34. Peptidyl beta-homo-aspartals (3-amino-4-carboxybutyraldehydes): new specific inhibitors of caspases.
Bajusz S; Fauszt I; Németh K; Barabás E; Juhász A; Patthy M; Bauer PI
Biopolymers; 1999; 51(1):109-18. PubMed ID: 10380358
[TBL] [Abstract][Full Text] [Related]
35. Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates.
Royo S; Schirmeister T; Kaiser M; Jung S; Rodríguez S; Bautista JM; González FV
Bioorg Med Chem; 2018 Sep; 26(16):4624-4634. PubMed ID: 30037754
[TBL] [Abstract][Full Text] [Related]
36. Structural analysis of caspase-1 inhibitors derived from Tethering.
O'Brien T; Fahr BT; Sopko MM; Lam JW; Waal ND; Raimundo BC; Purkey HE; Pham P; Romanowski MJ
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 May; 61(Pt 5):451-8. PubMed ID: 16511067
[TBL] [Abstract][Full Text] [Related]
37. Cyclopropenone-containing cysteine proteinase inhibitors. Synthesis and enzyme inhibitory activities.
Ando R; Sakaki T; Morinaka Y; Takahashi C; Tamao Y; Yoshii N; Katayama S; Saito K; Tokuyama H; Isaka M; Nakamura E
Bioorg Med Chem; 1999 Apr; 7(4):571-9. PubMed ID: 10353636
[TBL] [Abstract][Full Text] [Related]
38. Dioxo-triazines as a novel series of cathepsin K inhibitors.
Rankovic Z; Cai J; Fradera X; Dempster M; Mistry A; Mitchell A; Long C; Hamilton E; King A; Boucharens S; Jamieson C; Gillespie J; Cumming I; Uitdehaag J; van Zeeland M
Bioorg Med Chem Lett; 2010 Mar; 20(5):1488-90. PubMed ID: 20153187
[TBL] [Abstract][Full Text] [Related]
39. Structure-activity relationship study of a series of caspase inhibitors containing γ-amino acid moiety for treatment of cholestatic liver disease.
Mou J; Wu S; Luo Z; Guo F; He H; Wang J; Lin F; Guo F; Sun J; Shen L; Zeng M; Wang C; Xu D; Gu Z; Tian X; Zhang A; Xu H; Yang L; Zhang X; Li J; Chen S
Bioorg Med Chem Lett; 2018 Jun; 28(10):1874-1878. PubMed ID: 29650287
[TBL] [Abstract][Full Text] [Related]
40. Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates.
Gomaa MS; Lim AS; Lau SC; Watts AM; Illingworth NA; Bridgens CE; Veal GJ; Redfern CP; Brancale A; Armstrong JL; Simons C
Bioorg Med Chem; 2012 Oct; 20(20):6080-8. PubMed ID: 22989911
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
