343 related articles for article (PubMed ID: 20237084)
1. Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors.
Böttcher-Friebertshäuser E; Freuer C; Sielaff F; Schmidt S; Eickmann M; Uhlendorff J; Steinmetzer T; Klenk HD; Garten W
J Virol; 2010 Jun; 84(11):5605-14. PubMed ID: 20237084
[TBL] [Abstract][Full Text] [Related]
2. MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Böttcher E; Freuer C; Steinmetzer T; Klenk HD; Garten W
Vaccine; 2009 Oct; 27(45):6324-9. PubMed ID: 19840668
[TBL] [Abstract][Full Text] [Related]
3. Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics.
Garten W; Braden C; Arendt A; Peitsch C; Baron J; Lu Y; Pawletko K; Hardes K; Steinmetzer T; Böttcher-Friebertshäuser E
Eur J Cell Biol; 2015; 94(7-9):375-83. PubMed ID: 26095298
[TBL] [Abstract][Full Text] [Related]
4. Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells.
Bestle D; Limburg H; Kruhl D; Harbig A; Stein DA; Moulton H; Matrosovich M; Abdelwhab EM; Stech J; Böttcher-Friebertshäuser E
J Virol; 2021 Sep; 95(20):e0090621. PubMed ID: 34319155
[TBL] [Abstract][Full Text] [Related]
5. TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes.
Limburg H; Harbig A; Bestle D; Stein DA; Moulton HM; Jaeger J; Janga H; Hardes K; Koepke J; Schulte L; Koczulla AR; Schmeck B; Klenk HD; Böttcher-Friebertshäuser E
J Virol; 2019 Nov; 93(21):. PubMed ID: 31391268
[TBL] [Abstract][Full Text] [Related]
6. Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections.
Böttcher-Friebertshäuser E; Lu Y; Meyer D; Sielaff F; Steinmetzer T; Klenk HD; Garten W
Vaccine; 2012 Dec; 30(51):7374-80. PubMed ID: 23072892
[TBL] [Abstract][Full Text] [Related]
7. The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.
Kühn N; Bergmann S; Kösterke N; Lambertz RLO; Keppner A; van den Brand JMA; Pöhlmann S; Weiß S; Hummler E; Hatesuer B; Schughart K
J Virol; 2016 May; 90(9):4298-4307. PubMed ID: 26889029
[TBL] [Abstract][Full Text] [Related]
8. Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.
Böttcher E; Matrosovich T; Beyerle M; Klenk HD; Garten W; Matrosovich M
J Virol; 2006 Oct; 80(19):9896-8. PubMed ID: 16973594
[TBL] [Abstract][Full Text] [Related]
9. TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus.
Sato K; Hayashi H; Shimotai Y; Yamaya M; Hongo S; Kawakami K; Matsuzaki Y; Nishimura H
J Virol; 2021 Oct; 95(21):e0129621. PubMed ID: 34406864
[TBL] [Abstract][Full Text] [Related]
10. Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways.
Harbig A; Mernberger M; Bittel L; Pleschka S; Schughart K; Steinmetzer T; Stiewe T; Nist A; Böttcher-Friebertshäuser E
J Biol Chem; 2020 Aug; 295(33):11388-11407. PubMed ID: 32303635
[TBL] [Abstract][Full Text] [Related]
11. Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation.
Meyer D; Sielaff F; Hammami M; Böttcher-Friebertshäuser E; Garten W; Steinmetzer T
Biochem J; 2013 Jun; 452(2):331-43. PubMed ID: 23527573
[TBL] [Abstract][Full Text] [Related]
12. Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.
Baron J; Tarnow C; Mayoli-Nüssle D; Schilling E; Meyer D; Hammami M; Schwalm F; Steinmetzer T; Guan Y; Garten W; Klenk HD; Böttcher-Friebertshäuser E
J Virol; 2013 Feb; 87(3):1811-20. PubMed ID: 23192872
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.
Böttcher-Friebertshäuser E; Stein DA; Klenk HD; Garten W
J Virol; 2011 Feb; 85(4):1554-62. PubMed ID: 21123387
[TBL] [Abstract][Full Text] [Related]
14. ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells.
Heindl MR; Rupp A-L; Schwerdtner M; Bestle D; Harbig A; De Rocher A; Schmacke LC; Staker B; Steinmetzer T; Stein DA; Moulton HM; Böttcher-Friebertshäuser E
J Virol; 2024 Apr; 98(4):e0010224. PubMed ID: 38470058
[TBL] [Abstract][Full Text] [Related]
15. Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases.
Zhirnov OP; Ikizler MR; Wright PF
J Virol; 2002 Sep; 76(17):8682-9. PubMed ID: 12163588
[TBL] [Abstract][Full Text] [Related]
16. Proteolytic activation of the 1918 influenza virus hemagglutinin.
Chaipan C; Kobasa D; Bertram S; Glowacka I; Steffen I; Tsegaye TS; Takeda M; Bugge TH; Kim S; Park Y; Marzi A; Pöhlmann S
J Virol; 2009 Apr; 83(7):3200-11. PubMed ID: 19158246
[TBL] [Abstract][Full Text] [Related]
17. The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.
Sakai K; Ami Y; Tahara M; Kubota T; Anraku M; Abe M; Nakajima N; Sekizuka T; Shirato K; Suzaki Y; Ainai A; Nakatsu Y; Kanou K; Nakamura K; Suzuki T; Komase K; Nobusawa E; Maenaka K; Kuroda M; Hasegawa H; Kawaoka Y; Tashiro M; Takeda M
J Virol; 2014 May; 88(10):5608-16. PubMed ID: 24600012
[TBL] [Abstract][Full Text] [Related]
18. Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways.
Laporte M; Stevaert A; Raeymaekers V; Boogaerts T; Nehlmeier I; Chiu W; Benkheil M; Vanaudenaerde B; Pöhlmann S; Naesens L
J Virol; 2019 Dec; 94(1):. PubMed ID: 31597759
[TBL] [Abstract][Full Text] [Related]
19. TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1.
Zmora P; Hoffmann M; Kollmus H; Moldenhauer AS; Danov O; Braun A; Winkler M; Schughart K; Pöhlmann S
J Biol Chem; 2018 Sep; 293(36):13863-13873. PubMed ID: 29976755
[TBL] [Abstract][Full Text] [Related]
20. Activation of influenza viruses by proteases from host cells and bacteria in the human airway epithelium.
Böttcher-Friebertshäuser E; Klenk HD; Garten W
Pathog Dis; 2013 Nov; 69(2):87-100. PubMed ID: 23821437
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
