BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 20237649)

  • 1. An integrated one-step system to extract, analyze and annotate all relevant information from image-based cell screening of chemical libraries.
    Rabal O; Link W; Serelde BG; Bischoff JR; Oyarzabal J
    Mol Biosyst; 2010 Apr; 6(4):711-20. PubMed ID: 20237649
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia.
    Martelli AM; Evangelisti C; Chiarini F; Grimaldi C; Manzoli L; McCubrey JA
    Expert Opin Investig Drugs; 2009 Sep; 18(9):1333-49. PubMed ID: 19678801
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Integrating high-content screening and ligand-target prediction to identify mechanism of action.
    Young DW; Bender A; Hoyt J; McWhinnie E; Chirn GW; Tao CY; Tallarico JA; Labow M; Jenkins JL; Mitchison TJ; Feng Y
    Nat Chem Biol; 2008 Jan; 4(1):59-68. PubMed ID: 18066055
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of novel furoquinoline based inhibitors of multiple targets in the PI3K/Akt-mTOR pathway.
    Lohar MV; Mundada R; Bhonde M; Padgaonkar A; Deore V; Yewalkar N; Bhatia D; Rathos M; Joshi K; Vishwakarma RA; Kumar S
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3603-6. PubMed ID: 18501601
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinase inhibitor data modeling and de novo inhibitor design with fragment approaches.
    Vieth M; Erickson J; Wang J; Webster Y; Mader M; Higgs R; Watson I
    J Med Chem; 2009 Oct; 52(20):6456-66. PubMed ID: 19791746
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An automated feedback system with the hybrid model of scoring and classification for solving over-segmentation problems in RNAi high content screening.
    Li F; Zhou X; Ma J; Wong ST
    J Microsc; 2007 May; 226(Pt 2):121-32. PubMed ID: 17444941
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell-based high-content screening of small-molecule libraries.
    Korn K; Krausz E
    Curr Opin Chem Biol; 2007 Oct; 11(5):503-10. PubMed ID: 17931958
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Image analysis benchmarking methods for high-content screen design.
    Fuller CJ; Straight AF
    J Microsc; 2010 May; 238(2):145-61. PubMed ID: 20529062
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Drug discovery approaches targeting the PI3K/Akt pathway in cancer.
    Garcia-Echeverria C; Sellers WR
    Oncogene; 2008 Sep; 27(41):5511-26. PubMed ID: 18794885
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Creation of a digital slide and tissue microarray resource from a multi-institutional predictive toxicology study in the rat: an initial report from the PredTox group.
    Mulrane L; Rexhepaj E; Smart V; Callanan JJ; Orhan D; Eldem T; Mally A; Schroeder S; Meyer K; Wendt M; O'Shea D; Gallagher WM
    Exp Toxicol Pathol; 2008 Aug; 60(4-5):235-45. PubMed ID: 18479893
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer.
    Kim D; Cheng GZ; Lindsley CW; Yang H; Cheng JQ
    Curr Opin Investig Drugs; 2005 Dec; 6(12):1250-8. PubMed ID: 16370391
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification and validation of bioactive small molecule target through phenotypic screening.
    Cho YS; Kwon HJ
    Bioorg Med Chem; 2012 Mar; 20(6):1922-8. PubMed ID: 22153994
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphatidylinositol-3-kinase/Akt signaling pathway and kidney cancer, and the therapeutic potential of phosphatidylinositol-3-kinase/Akt inhibitors.
    Porta C; Figlin RA
    J Urol; 2009 Dec; 182(6):2569-77. PubMed ID: 19836781
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the PI3K-Akt pathway in kidney cancer.
    Park JY; Lin PY; Weiss RH
    Expert Rev Anticancer Ther; 2007 Jun; 7(6):863-70. PubMed ID: 17555396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting wall techoic acid biosynthesis: an in vivo based high-throughput screen for small molecule inhibitors.
    Chen W; Woodward R; Wang PG
    ACS Chem Biol; 2009 Nov; 4(11):893-4. PubMed ID: 19888733
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein translocation assays: key tools for accessing new biological information with high-throughput microscopy.
    Heydorn A; Lundholt BK; Praestegaard M; Pagliaro L
    Methods Enzymol; 2006; 414():513-30. PubMed ID: 17110209
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of a high-throughput screening assay for stearoyl-CoA desaturase using rat liver microsomes, deuterium labeled stearoyl-CoA and mass spectrometry.
    Soulard P; McLaughlin M; Stevens J; Connolly B; Coli R; Wang L; Moore J; Kuo MS; LaMarr WA; Ozbal CC; Bhat BG
    Anal Chim Acta; 2008 Oct; 627(1):105-11. PubMed ID: 18790133
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel inhibitors of human histone deacetylase (HDAC) identified by QSAR modeling of known inhibitors, virtual screening, and experimental validation.
    Tang H; Wang XS; Huang XP; Roth BL; Butler KV; Kozikowski AP; Jung M; Tropsha A
    J Chem Inf Model; 2009 Feb; 49(2):461-76. PubMed ID: 19182860
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Practicalities of drugging the phosphatidylinositol-3-kinase/Akt cell survival signaling pathway.
    Powis G; Ihle N; Kirkpatrick DL
    Clin Cancer Res; 2006 May; 12(10):2964-6. PubMed ID: 16707590
    [No Abstract]   [Full Text] [Related]  

  • 20. Issues in identification and linkage of patient records across an integrated delivery system.
    Arellano MG; Weber GI
    J Healthc Inf Manag; 1998; 12(3):43-52. PubMed ID: 10338786
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.