BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

387 related articles for article (PubMed ID: 2023902)

  • 1. PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues.
    Benjannet S; Rondeau N; Day R; Chrétien M; Seidah NG
    Proc Natl Acad Sci U S A; 1991 May; 88(9):3564-8. PubMed ID: 2023902
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin.
    Marcinkiewicz M; Day R; Seidah NG; Chrétien M
    Proc Natl Acad Sci U S A; 1993 Jun; 90(11):4922-6. PubMed ID: 8389457
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of prohormone convertases in pro-neuropeptide Y processing: coexpression and in vitro kinetic investigations.
    Brakch N; Rist B; Beck-Sickinger AG; Goenaga J; Wittek R; Bürger E; Brunner HR; Grouzmann E
    Biochemistry; 1997 Dec; 36(51):16309-20. PubMed ID: 9405066
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing.
    Zhou A; Bloomquist BT; Mains RE
    J Biol Chem; 1993 Jan; 268(3):1763-9. PubMed ID: 8380577
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro processing of proopiomelanocortin by recombinant PC1 (SPC3).
    Friedman TC; Loh YP; Birch NP
    Endocrinology; 1994 Sep; 135(3):854-62. PubMed ID: 8070378
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.
    Bloomquist BT; Eipper BA; Mains RE
    Mol Endocrinol; 1991 Dec; 5(12):2014-24. PubMed ID: 1791845
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoproteolytic processing of proopiomelanocortin and prohormone convertases 1 and 2 in neuroendocrine cells overexpressing prohormone convertases 1 or 2.
    Zhou A; Mains RE
    J Biol Chem; 1994 Jul; 269(26):17440-7. PubMed ID: 8021247
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The prohormone and proprotein processing enzymes PC1 and PC2: structure, selective cleavage of mouse POMC and human renin at pairs of basic residues, cellular expression, tissue distribution, and mRNA regulation.
    Seidah NG; Day R; Benjannet S; Rondeau N; Boudreault A; Reudelhuber T; Schafer MK; Watson SJ; Chrétien M
    NIDA Res Monogr; 1992; 126():132-50. PubMed ID: 1337150
    [No Abstract]   [Full Text] [Related]  

  • 9. The cDNA structure of the porcine pro-hormone convertase PC2 and the comparative processing by PC1 and PC2 of the N-terminal glycopeptide segment of porcine POMC.
    Seidah NG; Fournier H; Boileau G; Benjannet S; Rondeau N; Chrétien M
    FEBS Lett; 1992 Oct; 310(3):235-9. PubMed ID: 1397279
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene.
    Low MJ; Liu B; Hammer GD; Rubinstein M; Allen RG
    J Biol Chem; 1993 Nov; 268(33):24967-75. PubMed ID: 8227058
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mammalian neural and endocrine pro-protein and pro-hormone convertases belonging to the subtilisin family of serine proteinases.
    Seidah NG; Day R; Marcinkiewicz M; Benjannet S; Chrétien M
    Enzyme; 1991; 45(5-6):271-84. PubMed ID: 1843281
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary.
    Day R; Schafer MK; Watson SJ; Chrétien M; Seidah NG
    Mol Endocrinol; 1992 Mar; 6(3):485-97. PubMed ID: 1316544
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2.
    Benjannet S; Rondeau N; Paquet L; Boudreault A; Lazure C; Chrétien M; Seidah NG
    Biochem J; 1993 Sep; 294 ( Pt 3)(Pt 3):735-43. PubMed ID: 8397508
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes.
    Thomas L; Leduc R; Thorne BA; Smeekens SP; Steiner DF; Thomas G
    Proc Natl Acad Sci U S A; 1991 Jun; 88(12):5297-301. PubMed ID: 1647029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PC1/3 and PC2 gene expression and post-translational endoproteolytic pro-opiomelanocortin processing is regulated by photoperiod in the seasonal Siberian hamster (Phodopus sungorus).
    Helwig M; Khorooshi RM; Tups A; Barrett P; Archer ZA; Exner C; Rozman J; Braulke LJ; Mercer JG; Klingenspor M
    J Neuroendocrinol; 2006 Jun; 18(6):413-25. PubMed ID: 16684131
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1.
    Seidah NG; Benjannet S; Hamelin J; Mamarbachi AM; Basak A; Marcinkiewicz J; Mbikay M; Chrétien M; Marcinkiewicz M
    Ann N Y Acad Sci; 1999 Oct; 885():57-74. PubMed ID: 10816641
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of proopiomelanocortin and prohormone convertase-1 and -2 in the late gestation fetal sheep pituitary.
    Bell ME; Myers TR; Myers DA
    Endocrinology; 1998 Dec; 139(12):5135-43. PubMed ID: 9832453
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Spatiotemporal expression, distribution, and processing of POMC and POMC-derived peptides in murine skin.
    Mazurkiewicz JE; Corliss D; Slominski A
    J Histochem Cytochem; 2000 Jul; 48(7):905-14. PubMed ID: 10858267
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Profiles of pro-opiomelanocortin and encoded peptides, and their processing enzymes in equine pituitary pars intermedia dysfunction.
    Carmalt JL; Mortazavi S; McOnie RC; Allen AL; Unniappan S
    PLoS One; 2018; 13(1):e0190796. PubMed ID: 29309431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Maintained PC1 and PC2 expression in the AtT-20 variant cell line 6T3 lacking regulated secretion and POMC: restored POMC expression and regulated secretion after cAMP treatment.
    Day R; Benjannet S; Matsuuchi L; Kelly RB; Marcinkiewicz M; Chrétien M; Seidah NG
    DNA Cell Biol; 1995 Feb; 14(2):175-88. PubMed ID: 7865135
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.