These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 20298197)

  • 1. Substrate recognition and catalysis by flap endonucleases and related enzymes.
    Tomlinson CG; Atack JM; Chapados B; Tainer JA; Grasby JA
    Biochem Soc Trans; 2010 Apr; 38(2):433-7. PubMed ID: 20298197
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease.
    Williams R; Sengerová B; Osborne S; Syson K; Ault S; Kilgour A; Chapados BR; Tainer JA; Sayers JR; Grasby JA
    J Mol Biol; 2007 Aug; 371(1):34-48. PubMed ID: 17559871
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Flap endonucleases pass 5'-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5'-ends.
    Patel N; Atack JM; Finger LD; Exell JC; Thompson P; Tsutakawa S; Tainer JA; Williams DM; Grasby JA
    Nucleic Acids Res; 2012 May; 40(10):4507-19. PubMed ID: 22319208
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Three metal ions participate in the reaction catalyzed by T5 flap endonuclease.
    Syson K; Tomlinson C; Chapados BR; Sayers JR; Tainer JA; Williams NH; Grasby JA
    J Biol Chem; 2008 Oct; 283(42):28741-6. PubMed ID: 18697748
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases.
    Grasby JA; Finger LD; Tsutakawa SE; Atack JM; Tainer JA
    Trends Biochem Sci; 2012 Feb; 37(2):74-84. PubMed ID: 22118811
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.
    Liu R; Qiu J; Finger LD; Zheng L; Shen B
    Nucleic Acids Res; 2006; 34(6):1772-84. PubMed ID: 16582103
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity.
    Hohl M; Dunand-Sauthier I; Staresincic L; Jaquier-Gubler P; Thorel F; Modesti M; Clarkson SG; Schärer OD
    Nucleic Acids Res; 2007; 35(9):3053-63. PubMed ID: 17452369
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Concerted action of exonuclease and Gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments.
    Singh P; Zheng L; Chavez V; Qiu J; Shen B
    J Biol Chem; 2007 Feb; 282(6):3465-77. PubMed ID: 17138563
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Brønsted analysis and rate-limiting steps for the T5 flap endonuclease catalyzed hydrolysis of exonucleolytic substrates.
    Sengerová B; Tomlinson C; Atack JM; Williams R; Sayers JR; Williams NH; Grasby JA
    Biochemistry; 2010 Sep; 49(37):8085-93. PubMed ID: 20698567
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Double strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamily.
    Tsutakawa SE; Tainer JA
    Mech Ageing Dev; 2012 Apr; 133(4):195-202. PubMed ID: 22244820
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substrates.
    Devos JM; Tomanicek SJ; Jones CE; Nossal NG; Mueser TC
    J Biol Chem; 2007 Oct; 282(43):31713-24. PubMed ID: 17693399
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity.
    Hosfield DJ; Mol CD; Shen B; Tainer JA
    Cell; 1998 Oct; 95(1):135-46. PubMed ID: 9778254
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The wonders of flap endonucleases: structure, function, mechanism and regulation.
    Finger LD; Atack JM; Tsutakawa S; Classen S; Tainer J; Grasby J; Shen B
    Subcell Biochem; 2012; 62():301-26. PubMed ID: 22918592
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction interface of human flap endonuclease-1 with its DNA substrates.
    Qiu J; Liu R; Chapados BR; Sherman M; Tainer JA; Shen B
    J Biol Chem; 2004 Jun; 279(23):24394-402. PubMed ID: 15037610
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neutralizing mutations of carboxylates that bind metal 2 in T5 flap endonuclease result in an enzyme that still requires two metal ions.
    Tomlinson CG; Syson K; Sengerová B; Atack JM; Sayers JR; Swanson L; Tainer JA; Williams NH; Grasby JA
    J Biol Chem; 2011 Sep; 286(35):30878-30887. PubMed ID: 21734257
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression and biochemical characterization of the Plasmodium falciparum DNA repair enzyme, flap endonuclease-1 (PfFEN-1).
    Casta LJ; Buguliskis JS; Matsumoto Y; Taraschi TF
    Mol Biochem Parasitol; 2008 Jan; 157(1):1-12. PubMed ID: 17928073
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Active site substitutions delineate distinct classes of eubacterial flap endonuclease.
    Allen LM; Hodskinson MR; Sayers JR
    Biochem J; 2009 Mar; 418(2):285-92. PubMed ID: 19000038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I.
    Shi Y; Hellinga HW; Beese LS
    Proc Natl Acad Sci U S A; 2017 Jun; 114(23):6010-6015. PubMed ID: 28533382
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily.
    Tsutakawa SE; Classen S; Chapados BR; Arvai AS; Finger LD; Guenther G; Tomlinson CG; Thompson P; Sarker AH; Shen B; Cooper PK; Grasby JA; Tainer JA
    Cell; 2011 Apr; 145(2):198-211. PubMed ID: 21496641
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA structural elements required for FEN-1 binding.
    Harrington JJ; Lieber MR
    J Biol Chem; 1995 Mar; 270(9):4503-8. PubMed ID: 7876218
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.