BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

89 related articles for article (PubMed ID: 20301150)

  • 21. Synergism of virtual screening and medicinal chemistry: identification and optimization of allosteric antagonists of metabotropic glutamate receptor 1.
    Noeske T; Trifanova D; Kauss V; Renner S; Parsons CG; Schneider G; Weil T
    Bioorg Med Chem; 2009 Aug; 17(15):5708-15. PubMed ID: 19574055
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design and implementation of an ribonucleic acid (RNA) directed fragment library.
    Bodoor K; Boyapati V; Gopu V; Boisdore M; Allam K; Miller J; Treleaven WD; Weldeghiorghis T; Aboul-ela F
    J Med Chem; 2009 Jun; 52(12):3753-61. PubMed ID: 19445516
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development and experimental validation of a docking strategy for the generation of kinase-targeted libraries.
    Gozalbes R; Simon L; Froloff N; Sartori E; Monteils C; Baudelle R
    J Med Chem; 2008 Jun; 51(11):3124-32. PubMed ID: 18479119
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Flexible alignment of small molecules using the penalty method.
    Shin W; Hyun SA; Chae CH; Chon JK
    J Chem Inf Model; 2009 Aug; 49(8):1879-88. PubMed ID: 19645428
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Selection of DNA-encoded small molecule libraries against unmodified and non-immobilized protein targets.
    Zhao P; Chen Z; Li Y; Sun D; Gao Y; Huang Y; Li X
    Angew Chem Int Ed Engl; 2014 Sep; 53(38):10056-9. PubMed ID: 25044298
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Screening the receptorome.
    Kroeze WK; Roth BL
    J Psychopharmacol; 2006 Jul; 20(4 Suppl):41-6. PubMed ID: 16785269
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The human growth hormone saga.
    Canova-Davis E
    Dev Biol Stand; 1998; 96():105-11. PubMed ID: 9890523
    [No Abstract]   [Full Text] [Related]  

  • 28. Discovery of small molecule inhibitors of protein-protein interactions using combined ligand and target score normalization.
    Casey FP; Pihan E; Shields DC
    J Chem Inf Model; 2009 Dec; 49(12):2708-17. PubMed ID: 19994847
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Homology modeling of the serotonin 5-HT1A receptor using automated docking of bioactive compounds with defined geometry.
    Nowak M; Kołaczkowski M; Pawłowski M; Bojarski AJ
    J Med Chem; 2006 Jan; 49(1):205-14. PubMed ID: 16392805
    [TBL] [Abstract][Full Text] [Related]  

  • 30. MED-3DMC: a new tool to generate 3D conformation ensembles of small molecules with a Monte Carlo sampling of the conformational space.
    Sperandio O; Souaille M; Delfaud F; Miteva MA; Villoutreix BO
    Eur J Med Chem; 2009 Apr; 44(4):1405-9. PubMed ID: 19022539
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A library of chiral imidazoline-aminophenol ligands: discovery of an efficient reaction sphere.
    Arai T; Yokoyama N; Yanagisawa A
    Chemistry; 2008; 14(7):2052-9. PubMed ID: 18186090
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Strategies to search and design stabilizers of protein-protein interactions: a feasibility study.
    Block P; Weskamp N; Wolf A; Klebe G
    Proteins; 2007 Jul; 68(1):170-86. PubMed ID: 17393392
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synergistic effect of binary component ligands in chiral catalyst library engineering for enantioselective reactions.
    Ding K
    Chem Commun (Camb); 2008 Feb; (8):909-21. PubMed ID: 18283341
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Prediction of protein-protein interface sequence diversity using flexible backbone computational protein design.
    Humphris EL; Kortemme T
    Structure; 2008 Dec; 16(12):1777-88. PubMed ID: 19081054
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Computational analysis of ligand binding dynamics at the intermolecular hot spots with the aid of simulated tempering and binding free energy calculations.
    Verkhivker GM
    J Mol Graph Model; 2004 May; 22(5):335-48. PubMed ID: 15099830
    [TBL] [Abstract][Full Text] [Related]  

  • 36. ProPose: steered virtual screening by simultaneous protein-ligand docking and ligand-ligand alignment.
    Seifert MH
    J Chem Inf Model; 2005; 45(2):449-60. PubMed ID: 15807511
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design and NMR-based screening of LEF, a library of chemical fragments with different local environment of fluorine.
    Vulpetti A; Hommel U; Landrum G; Lewis R; Dalvit C
    J Am Chem Soc; 2009 Sep; 131(36):12949-59. PubMed ID: 19702332
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Kinase inhibitor data modeling and de novo inhibitor design with fragment approaches.
    Vieth M; Erickson J; Wang J; Webster Y; Mader M; Higgs R; Watson I
    J Med Chem; 2009 Oct; 52(20):6456-66. PubMed ID: 19791746
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Recent trends in library design: 'rational design' revisited.
    Schnur DM
    Curr Opin Drug Discov Devel; 2008 May; 11(3):375-80. PubMed ID: 18428091
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A novel modeling protocol for protein receptors guided by bound-ligand conformation.
    Johnson MA; Höög C; Pinto BM
    Biochemistry; 2003 Feb; 42(7):1842-53. PubMed ID: 12590571
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.