BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 20304656)

  • 1. Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10.
    Endo S; Matsunaga T; Kuwata K; Zhao HT; El-Kabbani O; Kitade Y; Hara A
    Bioorg Med Chem; 2010 Apr; 18(7):2485-90. PubMed ID: 20304656
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and structure-activity relationship of 2-phenyliminochromene derivatives as inhibitors for aldo-keto reductase (AKR) 1B10.
    Endo S; Hu D; Suyama M; Matsunaga T; Sugimoto K; Matsuya Y; El-Kabbani O; Kuwata K; Hara A; Kitade Y; Toyooka N
    Bioorg Med Chem; 2013 Nov; 21(21):6378-84. PubMed ID: 24071447
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1.
    Hu D; Miyagi N; Arai Y; Oguri H; Miura T; Nishinaka T; Terada T; Gouda H; El-Kabbani O; Xia S; Toyooka N; Hara A; Matsunaga T; Ikari A; Endo S
    Org Biomol Chem; 2015 Jul; 13(27):7487-99. PubMed ID: 26068795
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroids.
    Endo S; Matsunaga T; Mamiya H; Ohta C; Soda M; Kitade Y; Tajima K; Zhao HT; El-Kabbani O; Hara A
    Arch Biochem Biophys; 2009 Jul; 487(1):1-9. PubMed ID: 19464995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selectivity determinants of inhibitor binding to the tumour marker human aldose reductase-like protein (AKR1B10) discovered from molecular docking and database screening.
    Zhao HT; Soda M; Endo S; Hara A; El-Kabbani O
    Eur J Med Chem; 2010 Sep; 45(9):4354-7. PubMed ID: 20538382
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B10.
    Soda M; Hu D; Endo S; Takemura M; Li J; Wada R; Ifuku S; Zhao HT; El-Kabbani O; Ohta S; Yamamura K; Toyooka N; Hara A; Matsunaga T
    Eur J Med Chem; 2012 Feb; 48():321-9. PubMed ID: 22236472
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective inhibition of the tumor marker AKR1B10 by antiinflammatory N-phenylanthranilic acids and glycyrrhetic acid.
    Endo S; Matsunaga T; Soda M; Tajima K; Zhao HT; El-Kabbani O; Hara A
    Biol Pharm Bull; 2010; 33(5):886-90. PubMed ID: 20460771
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: probing the active site of the enzyme with molecular modeling and site-directed mutagenesis.
    Matsunaga T; Endo S; Soda M; Zhao HT; El-Kabbani O; Tajima K; Hara A
    Biochem Biophys Res Commun; 2009 Nov; 389(1):128-32. PubMed ID: 19706287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.
    Endo S; Xia S; Suyama M; Morikawa Y; Oguri H; Hu D; Ao Y; Takahara S; Horino Y; Hayakawa Y; Watanabe Y; Gouda H; Hara A; Kuwata K; Toyooka N; Matsunaga T; Ikari A
    J Med Chem; 2017 Oct; 60(20):8441-8455. PubMed ID: 28976752
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of steroidal derivatives as selective inhibitors of AKR1B10.
    Zhang W; Wang L; Zhang L; Chen W; Chen X; Xie M; Yan G; Hu X; Xu J; Zhang J
    Steroids; 2014 Aug; 86():39-44. PubMed ID: 24793566
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
    Takemura M; Endo S; Matsunaga T; Soda M; Zhao HT; El-Kabbani O; Tajima K; Iinuma M; Hara A
    J Nat Prod; 2011 May; 74(5):1201-6. PubMed ID: 21561086
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of aldo-keto reductase family 1 member B10 by unsaturated fatty acids.
    Hara A; Endo S; Matsunaga T; Soda M; El-Kabbani O; Yashiro K
    Arch Biochem Biophys; 2016 Nov; 609():69-76. PubMed ID: 27665999
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of compound selectivity of aldo-keto reductases using differential scanning fluorimetry.
    Kabir A; Endo S; Toyooka N; Fukuoka M; Kuwata K; Kamatari YO
    J Biochem; 2017 Feb; 161(2):215-222. PubMed ID: 28003428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: role of Trp112 (Trp111).
    Zhang L; Zhang H; Zhao Y; Li Z; Chen S; Zhai J; Chen Y; Xie W; Wang Z; Li Q; Zheng X; Hu X
    FEBS Lett; 2013 Nov; 587(22):3681-6. PubMed ID: 24100137
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase.
    Giménez-Dejoz J; Kolář MH; Ruiz FX; Crespo I; Cousido-Siah A; Podjarny A; Barski OA; Fanfrlík J; Parés X; Farrés J; Porté S
    PLoS One; 2015; 10(7):e0134506. PubMed ID: 26222439
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment.
    Huang L; He R; Luo W; Zhu YS; Li J; Tan T; Zhang X; Hu Z; Luo D
    Recent Pat Anticancer Drug Discov; 2016; 11(2):184-96. PubMed ID: 26844556
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity.
    Díez-Dacal B; Gayarre J; Gharbi S; Timms JF; Coderch C; Gago F; Pérez-Sala D
    Cancer Res; 2011 Jun; 71(12):4161-71. PubMed ID: 21507934
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers.
    Verma M; Martin HJ; Haq W; O'Connor TR; Maser E; Balendiran GK
    Eur J Pharmacol; 2008 Apr; 584(2-3):213-21. PubMed ID: 18325492
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of rabbit aldose reductase-like protein with 3β-hydroxysteroid dehydrogenase activity.
    Endo S; Matsunaga T; Kumada S; Fujimoto A; Ohno S; El-Kabbani O; Hu D; Toyooka N; Mano J; Tajima K; Hara A
    Arch Biochem Biophys; 2012 Nov; 527(1):23-30. PubMed ID: 22874434
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for the inhibition of AKR1B10 by caffeic acid phenethyl ester (CAPE).
    Zhang L; Zhang H; Zheng X; Zhao Y; Chen S; Chen Y; Zhang R; Li Q; Hu X
    ChemMedChem; 2014 Apr; 9(4):706-9. PubMed ID: 24436249
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.