BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 20338997)

  • 1. mTOR complex-2 activates ENaC by phosphorylating SGK1.
    Lu M; Wang J; Jones KT; Ives HE; Feldman ME; Yao LJ; Shokat KM; Ashrafi K; Pearce D
    J Am Soc Nephrol; 2010 May; 21(5):811-8. PubMed ID: 20338997
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM; Alessi DR
    Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin upregulates the expression of epithelial sodium channel in vitro and in a mouse model of acute lung injury: role of mTORC2/SGK1 pathway.
    He J; Qi D; Wang DX; Deng W; Ye Y; Feng LH; Zhu T; Zhao Y; Zhang CR
    Exp Cell Res; 2015 Feb; 331(1):164-175. PubMed ID: 25265063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of the epithelial Na+ channel by the mTORC2/SGK1 pathway.
    Lang F; Pearce D
    Nephrol Dial Transplant; 2016 Feb; 31(2):200-5. PubMed ID: 26163195
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.
    Gleason CE; Frindt G; Cheng CJ; Ng M; Kidwai A; Rashmi P; Lang F; Baum M; Palmer LG; Pearce D
    J Clin Invest; 2015 Jan; 125(1):117-28. PubMed ID: 25415435
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.
    Lu M; Wang J; Ives HE; Pearce D
    J Biol Chem; 2011 Sep; 286(35):30647-30654. PubMed ID: 21757730
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potassium Activates mTORC2-dependent SGK1 Phosphorylation to Stimulate Epithelial Sodium Channel: Role in Rapid Renal Responses to Dietary Potassium.
    Saha B; Shabbir W; Takagi E; Duan XP; Leite Dellova DCA; Demko J; Manis A; Loffing-Cueni D; Loffing J; Sørensen MV; Wang WH; Pearce D
    J Am Soc Nephrol; 2023 Jun; 34(6):1019-1038. PubMed ID: 36890646
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potassium acts through mTOR to regulate its own secretion.
    Sørensen MV; Saha B; Jensen IS; Wu P; Ayasse N; Gleason CE; Svendsen SL; Wang WH; Pearce D
    JCI Insight; 2019 Apr; 5(11):. PubMed ID: 31013253
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of the proteasome stimulate the epithelial sodium channel (ENaC) through SGK1 and mimic the effect of aldosterone.
    Mansley MK; Korbmacher C; Bertog M
    Pflugers Arch; 2018 Feb; 470(2):295-304. PubMed ID: 28861610
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epithelial Na⁺ channel activity in human airway epithelial cells: the role of serum and glucocorticoid-inducible kinase 1.
    Watt GB; Ismail NA; Caballero AG; Land SC; Wilson SM
    Br J Pharmacol; 2012 Jun; 166(4):1272-89. PubMed ID: 22250980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport.
    Saha B; Leite-Dellova DCA; Demko J; Sørensen MV; Takagi E; Gleason CE; Shabbir W; Pearce D
    J Cell Sci; 2022 Dec; 135(23):. PubMed ID: 36373794
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
    Pearce LR; Sommer EM; Sakamoto K; Wullschleger S; Alessi DR
    Biochem J; 2011 May; 436(1):169-79. PubMed ID: 21413931
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression.
    Hall BA; Kim TY; Skor MN; Conzen SD
    Breast Cancer Res Treat; 2012 Sep; 135(2):469-79. PubMed ID: 22842983
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase.
    Mori S; Nada S; Kimura H; Tajima S; Takahashi Y; Kitamura A; Oneyama C; Okada M
    PLoS One; 2014; 9(2):e88891. PubMed ID: 24558442
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3.
    Bhalla V; Daidié D; Li H; Pao AC; LaGrange LP; Wang J; Vandewalle A; Stockand JD; Staub O; Pearce D
    Mol Endocrinol; 2005 Dec; 19(12):3073-84. PubMed ID: 16099816
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex.
    Soundararajan R; Ziera T; Koo E; Ling K; Wang J; Borden SA; Pearce D
    J Biol Chem; 2012 Sep; 287(39):33014-25. PubMed ID: 22851176
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epithelial sodium channel regulation by cell surface-associated serum- and glucocorticoid-regulated kinase 1.
    Thomas SV; Kathpalia PP; Rajagopal M; Charlton C; Zhang J; Eaton DC; Helms MN; Pao AC
    J Biol Chem; 2011 Sep; 286(37):32074-85. PubMed ID: 21784856
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt.
    Yu Z; Chen J; Takagi E; Wang F; Saha B; Liu X; Joubert LM; Gleason CE; Jin M; Li C; Nowotny C; Agard D; Cheng Y; Pearce D
    J Biol Chem; 2022 Sep; 298(9):102288. PubMed ID: 35926713
    [TBL] [Abstract][Full Text] [Related]  

  • 19. COMMD1 downregulates the epithelial sodium channel through Nedd4-2.
    Ke Y; Butt AG; Swart M; Liu YF; McDonald FJ
    Am J Physiol Renal Physiol; 2010 Jun; 298(6):F1445-56. PubMed ID: 20237237
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New insights into the role of serum- and glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure.
    Vallon V; Lang F
    Curr Opin Nephrol Hypertens; 2005 Jan; 14(1):59-66. PubMed ID: 15586017
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.