417 related articles for article (PubMed ID: 20346729)
21. [Fragment-based lead discovery from smaller fragments to functional ligand].
Hatayama A; Habashita H
Tanpakushitsu Kakusan Koso; 2009 Sep; 54(12 Suppl):1611-6. PubMed ID: 21089596
[No Abstract] [Full Text] [Related]
22. The discovery of antibacterial agents using diversity-oriented synthesis.
Galloway WR; Bender A; Welch M; Spring DR
Chem Commun (Camb); 2009 May; (18):2446-62. PubMed ID: 19532856
[TBL] [Abstract][Full Text] [Related]
23. PNA-encoded chemical libraries.
Zambaldo C; Barluenga S; Winssinger N
Curr Opin Chem Biol; 2015 Jun; 26():8-15. PubMed ID: 25621730
[TBL] [Abstract][Full Text] [Related]
24. Discovery of small molecule inhibitors of protein-protein interactions using combined ligand and target score normalization.
Casey FP; Pihan E; Shields DC
J Chem Inf Model; 2009 Dec; 49(12):2708-17. PubMed ID: 19994847
[TBL] [Abstract][Full Text] [Related]
25. Experiences in fragment-based lead discovery.
Hubbard RE; Murray JB
Methods Enzymol; 2011; 493():509-31. PubMed ID: 21371604
[TBL] [Abstract][Full Text] [Related]
26. Current parallel chemistry principles and practice: application to the discovery of biologically active molecules.
Edwards PJ
Curr Opin Drug Discov Devel; 2009 Nov; 12(6):899-914. PubMed ID: 19894197
[TBL] [Abstract][Full Text] [Related]
27. Structure-based tailoring of compound libraries for high-throughput screening: discovery of novel EphB4 kinase inhibitors.
Kolb P; Kipouros CB; Huang D; Caflisch A
Proteins; 2008 Oct; 73(1):11-8. PubMed ID: 18384152
[TBL] [Abstract][Full Text] [Related]
28. Ligand specificity, privileged substructures and protein druggability from fragment-based screening.
Barelier S; Krimm I
Curr Opin Chem Biol; 2011 Aug; 15(4):469-74. PubMed ID: 21411360
[TBL] [Abstract][Full Text] [Related]
29. PGVL Hub: An integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds.
Peng Z; Yang B; Mattaparti S; Shulok T; Thacher T; Kong J; Kostrowicki J; Hu Q; Na J; Zhou JZ; Klatte D; Chao B; Ito S; Clark J; Sciammetta N; Coner B; Waller C; Kuki A
Methods Mol Biol; 2011; 685():295-320. PubMed ID: 20981530
[TBL] [Abstract][Full Text] [Related]
30. Docking methods for structure-based library design.
Cavasotto CN; Phatak SS
Methods Mol Biol; 2011; 685():155-74. PubMed ID: 20981523
[TBL] [Abstract][Full Text] [Related]
31. Diversity-oriented synthesis; a spectrum of approaches and results.
Spandl RJ; Bender A; Spring DR
Org Biomol Chem; 2008 Apr; 6(7):1149-58. PubMed ID: 18362950
[TBL] [Abstract][Full Text] [Related]
32. Two 'Golden Ratio' indices in fragment-based drug discovery.
Orita M; Ohno K; Niimi T
Drug Discov Today; 2009 Mar; 14(5-6):321-8. PubMed ID: 19028598
[TBL] [Abstract][Full Text] [Related]
33. Historical overview of chemical library design.
Dolle RE
Methods Mol Biol; 2011; 685():3-25. PubMed ID: 20981516
[TBL] [Abstract][Full Text] [Related]
34. Target identification of bioactive compounds.
Tashiro E; Imoto M
Bioorg Med Chem; 2012 Mar; 20(6):1910-21. PubMed ID: 22104438
[TBL] [Abstract][Full Text] [Related]
35. DNA-encoded chemical libraries.
Scheuermann J; Dumelin CE; Melkko S; Neri D
J Biotechnol; 2006 Dec; 126(4):568-81. PubMed ID: 16860425
[TBL] [Abstract][Full Text] [Related]
36. Selection of DNA-encoded small molecule libraries against unmodified and non-immobilized protein targets.
Zhao P; Chen Z; Li Y; Sun D; Gao Y; Huang Y; Li X
Angew Chem Int Ed Engl; 2014 Sep; 53(38):10056-9. PubMed ID: 25044298
[TBL] [Abstract][Full Text] [Related]
37. Fidelity by design: Yoctoreactor and binder trap enrichment for small-molecule DNA-encoded libraries and drug discovery.
Blakskjaer P; Heitner T; Hansen NJ
Curr Opin Chem Biol; 2015 Jun; 26():62-71. PubMed ID: 25732963
[TBL] [Abstract][Full Text] [Related]
38. Novel encoding methods for DNA-templated chemical libraries.
Li G; Zheng W; Liu Y; Li X
Curr Opin Chem Biol; 2015 Jun; 26():25-33. PubMed ID: 25635927
[TBL] [Abstract][Full Text] [Related]
39. A scalable approach to combinatorial library design.
Sharma P; Salapaka S; Beck C
Methods Mol Biol; 2011; 685():71-89. PubMed ID: 20981519
[TBL] [Abstract][Full Text] [Related]
40. Recent progress in the discovery and development of negative allosteric modulators of mGluR5.
Lindsley CW; Emmitte KA
Curr Opin Drug Discov Devel; 2009 Jul; 12(4):446-57. PubMed ID: 19562641
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]