188 related articles for article (PubMed ID: 20348445)
1. Reduced seed region-based off-target activity with lentivirus-mediated RNAi.
Klinghoffer RA; Magnus J; Schelter J; Mehaffey M; Coleman C; Cleary MA
RNA; 2010 May; 16(5):879-84. PubMed ID: 20348445
[TBL] [Abstract][Full Text] [Related]
2. Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity.
Jackson AL; Burchard J; Schelter J; Chau BN; Cleary M; Lim L; Linsley PS
RNA; 2006 Jul; 12(7):1179-87. PubMed ID: 16682560
[TBL] [Abstract][Full Text] [Related]
3. Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing.
Jackson AL; Burchard J; Leake D; Reynolds A; Schelter J; Guo J; Johnson JM; Lim L; Karpilow J; Nichols K; Marshall W; Khvorova A; Linsley PS
RNA; 2006 Jul; 12(7):1197-205. PubMed ID: 16682562
[TBL] [Abstract][Full Text] [Related]
4. Design of lentivirally expressed siRNAs.
Liu YP; Berkhout B
Methods Mol Biol; 2013; 942():233-57. PubMed ID: 23027055
[TBL] [Abstract][Full Text] [Related]
5. Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors.
Fish RJ; Kruithof EK
BMC Mol Biol; 2004 Aug; 5():9. PubMed ID: 15291968
[TBL] [Abstract][Full Text] [Related]
6. Retrovirus vector-mediated stable gene silencing in human cell.
Liu CM; Liu DP; Dong WJ; Liang CC
Biochem Biophys Res Commun; 2004 Jan; 313(3):716-20. PubMed ID: 14697249
[TBL] [Abstract][Full Text] [Related]
7. Enhancement of allele discrimination by introduction of nucleotide mismatches into siRNA in allele-specific gene silencing by RNAi.
Ohnishi Y; Tamura Y; Yoshida M; Tokunaga K; Hohjoh H
PLoS One; 2008 May; 3(5):e2248. PubMed ID: 18493311
[TBL] [Abstract][Full Text] [Related]
8. Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis.
Yilmazel B; Hu Y; Sigoillot F; Smith JA; Shamu CE; Perrimon N; Mohr SE
BMC Bioinformatics; 2014 Jun; 15():192. PubMed ID: 24934636
[TBL] [Abstract][Full Text] [Related]
9. HIV-1 RRE RNA acts as an RNA silencing suppressor by competing with TRBP-bound siRNAs.
Daniels SM; Sinck L; Ward NJ; Melendez-Peña CE; Scarborough RJ; Azar I; Rance E; Daher A; Pang KM; Rossi JJ; Gatignol A
RNA Biol; 2015; 12(2):123-35. PubMed ID: 25668122
[TBL] [Abstract][Full Text] [Related]
10. A small molecule enhances RNA interference and promotes microRNA processing.
Shan G; Li Y; Zhang J; Li W; Szulwach KE; Duan R; Faghihi MA; Khalil AM; Lu L; Paroo Z; Chan AW; Shi Z; Liu Q; Wahlestedt C; He C; Jin P
Nat Biotechnol; 2008 Aug; 26(8):933-40. PubMed ID: 18641635
[TBL] [Abstract][Full Text] [Related]
11. Experimental validation of the importance of seed complement frequency to siRNA specificity.
Anderson EM; Birmingham A; Baskerville S; Reynolds A; Maksimova E; Leake D; Fedorov Y; Karpilow J; Khvorova A
RNA; 2008 May; 14(5):853-61. PubMed ID: 18367722
[TBL] [Abstract][Full Text] [Related]
12. siRNA off-target effects can be reduced at concentrations that match their individual potency.
Caffrey DR; Zhao J; Song Z; Schaffer ME; Haney SA; Subramanian RR; Seymour AB; Hughes JD
PLoS One; 2011; 6(7):e21503. PubMed ID: 21750714
[TBL] [Abstract][Full Text] [Related]
13. [The construction of lentivirus-mediated RNAi vector containing hTERT].
Zhao P; Fu Z; You YP; Wang CZ; Cheng YX; Lu XM; Lu A; Liu N
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2008 Feb; 25(1):27-31. PubMed ID: 18247299
[TBL] [Abstract][Full Text] [Related]
14. Transduction with Lentiviral Vectors Altered the Expression Profile of Host MicroRNAs.
Huang H; Zhang C; Wang B; Wang F; Pei B; Cheng C; Yang W; Zhao Z
J Virol; 2018 Sep; 92(18):. PubMed ID: 29997205
[TBL] [Abstract][Full Text] [Related]
15. siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect.
Naito Y; Yoshimura J; Morishita S; Ui-Tei K
BMC Bioinformatics; 2009 Nov; 10():392. PubMed ID: 19948054
[TBL] [Abstract][Full Text] [Related]
16. A facile lentiviral vector system for expression of doxycycline-inducible shRNAs: knockdown of the pre-miRNA processing enzyme Drosha.
Aagaard L; Amarzguioui M; Sun G; Santos LC; Ehsani A; Prydz H; Rossi JJ
Mol Ther; 2007 May; 15(5):938-45. PubMed ID: 17311008
[TBL] [Abstract][Full Text] [Related]
17. The siRNA Non-seed Region and Its Target Sequences Are Auxiliary Determinants of Off-Target Effects.
Kamola PJ; Nakano Y; Takahashi T; Wilson PA; Ui-Tei K
PLoS Comput Biol; 2015 Dec; 11(12):e1004656. PubMed ID: 26657993
[TBL] [Abstract][Full Text] [Related]
18. [Lentivirus Delivery of the Short Hairpin RNA Targeting NDV P Gene Inhibits Production of the Newcastle Disease Virus in Chicken Embryo Fibroblasts and Chicken Embryos].
Yang S; Xu C; Zhang L; Huang Y; Huang Q; Hu B; Zhang X
Bing Du Xue Bao; 2016 Jan; 32(1):39-45. PubMed ID: 27295882
[TBL] [Abstract][Full Text] [Related]
19. Lentiviral-mediated BCL2 gene knockdown using comparative microRNA adaptive shRNAs.
Abdolhossein Zadeh B; Yavari K; Banan M; Fallah A; Nasehi L; Absalan M; Tavoosidana G
Cell Mol Biol (Noisy-le-grand); 2018 Aug; 64(11):25-30. PubMed ID: 30213285
[TBL] [Abstract][Full Text] [Related]
20. The RNA silencing technology applied by lentiviral vectors in oncology.
Sumimoto H; Kawakami Y
Methods Mol Biol; 2010; 614():187-99. PubMed ID: 20225045
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]