BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 20351172)

  • 1. The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.
    Wu-Baer F; Ludwig T; Baer R
    Mol Cell Biol; 2010 Jun; 30(11):2787-98. PubMed ID: 20351172
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase.
    Nishikawa H; Ooka S; Sato K; Arima K; Okamoto J; Klevit RE; Fukuda M; Ohta T
    J Biol Chem; 2004 Feb; 279(6):3916-24. PubMed ID: 14638690
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.
    Wu-Baer F; Lagrazon K; Yuan W; Baer R
    J Biol Chem; 2003 Sep; 278(37):34743-6. PubMed ID: 12890688
    [TBL] [Abstract][Full Text] [Related]  

  • 4. E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.
    Christensen DE; Brzovic PS; Klevit RE
    Nat Struct Mol Biol; 2007 Oct; 14(10):941-8. PubMed ID: 17873885
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression.
    Choudhury AD; Xu H; Baer R
    J Biol Chem; 2004 Aug; 279(32):33909-18. PubMed ID: 15166217
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains.
    Mallery DL; Vandenberg CJ; Hiom K
    EMBO J; 2002 Dec; 21(24):6755-62. PubMed ID: 12485996
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.
    Stewart MD; Duncan ED; Coronado E; DaRosa PA; Pruneda JN; Brzovic PS; Klevit RE
    Protein Sci; 2017 Mar; 26(3):475-483. PubMed ID: 27977889
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1.
    Dizin E; Irminger-Finger I
    Int J Biochem Cell Biol; 2010 May; 42(5):693-700. PubMed ID: 20060929
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.
    Hayami R; Sato K; Wu W; Nishikawa T; Hiroi J; Ohtani-Kaneko R; Fukuda M; Ohta T
    Cancer Res; 2005 Jan; 65(1):6-10. PubMed ID: 15665273
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase.
    Sato K; Hayami R; Wu W; Nishikawa T; Nishikawa H; Okuda Y; Ogata H; Fukuda M; Ohta T
    J Biol Chem; 2004 Jul; 279(30):30919-22. PubMed ID: 15184379
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BRCA1 DNA-binding activity is stimulated by BARD1.
    Simons AM; Horwitz AA; Starita LM; Griffin K; Williams RS; Glover JN; Parvin JD
    Cancer Res; 2006 Feb; 66(4):2012-8. PubMed ID: 16489000
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase.
    Chen A; Kleiman FE; Manley JL; Ouchi T; Pan ZQ
    J Biol Chem; 2002 Jun; 277(24):22085-92. PubMed ID: 11927591
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.
    Nishikawa H; Wu W; Koike A; Kojima R; Gomi H; Fukuda M; Ohta T
    Cancer Res; 2009 Jan; 69(1):111-9. PubMed ID: 19117993
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
    Hu Q; Botuyan MV; Zhao D; Cui G; Mer E; Mer G
    Nature; 2021 Aug; 596(7872):438-443. PubMed ID: 34321665
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.
    Morris JR; Solomon E
    Hum Mol Genet; 2004 Apr; 13(8):807-17. PubMed ID: 14976165
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity.
    Baer R; Ludwig T
    Curr Opin Genet Dev; 2002 Feb; 12(1):86-91. PubMed ID: 11790560
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The BRCA1/BARD1 ubiquitin ligase and its substrates.
    Witus SR; Stewart MD; Klevit RE
    Biochem J; 2021 Sep; 478(18):3467-3483. PubMed ID: 34591954
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis.
    Salas-Lloret D; García-Rodríguez N; Soto-Hidalgo E; González-Vinceiro L; Espejo-Serrano C; Giebel L; Mateos-Martín ML; de Ru AH; van Veelen PA; Huertas P; Vertegaal ACO; González-Prieto R
    Nat Commun; 2024 May; 15(1):4292. PubMed ID: 38769345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation.
    Hashizume R; Fukuda M; Maeda I; Nishikawa H; Oyake D; Yabuki Y; Ogata H; Ohta T
    J Biol Chem; 2001 May; 276(18):14537-40. PubMed ID: 11278247
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line.
    Li Q; Kaur A; Okada K; McKenney RJ; Engebrecht J
    PLoS Genet; 2023 Jan; 19(1):e1010457. PubMed ID: 36716349
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.