BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 20352290)

  • 1. The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity.
    Tubert P; Rodríguez M; Ribó M; Benito A; Vilanova M
    Invest New Drugs; 2011 Oct; 29(5):811-7. PubMed ID: 20352290
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Generation of new cytotoxic human ribonuclease variants directed to the nucleus.
    Vert A; Castro J; Ruiz-Martínez S; Tubert P; Escribano D; Ribó M; Vilanova M; Benito A
    Mol Pharm; 2012 Oct; 9(10):2894-902. PubMed ID: 22957849
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity.
    Bosch M; Benito A; Ribó M; Puig T; Beaumelle B; Vilanova M
    Biochemistry; 2004 Mar; 43(8):2167-77. PubMed ID: 14979713
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A cytotoxic ribonuclease variant with a discontinuous nuclear localization signal constituted by basic residues scattered over three areas of the molecule.
    Rodríguez M; Benito A; Tubert P; Castro J; Ribó M; Beaumelle B; Vilanova M
    J Mol Biol; 2006 Jul; 360(3):548-57. PubMed ID: 16780873
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells.
    Vert A; Castro J; Ribó M; Benito A; Vilanova M
    Oncotarget; 2016 Apr; 7(14):18309-24. PubMed ID: 26918450
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of the N terminus in RNase A homologues: differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity.
    Boix E; Wu Y; Vasandani VM; Saxena SK; Ardelt W; Ladner J; Youle RJ
    J Mol Biol; 1996 Apr; 257(5):992-1007. PubMed ID: 8632481
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of human pancreatic ribonuclease with human ribonuclease inhibitor. Generation of inhibitor-resistant cytotoxic variants.
    Gaur D; Swaminathan S; Batra JK
    J Biol Chem; 2001 Jul; 276(27):24978-84. PubMed ID: 11342552
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.
    Johnson RJ; McCoy JG; Bingman CA; Phillips GN; Raines RT
    J Mol Biol; 2007 Apr; 368(2):434-49. PubMed ID: 17350650
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of ribonuclease cytotoxicity.
    Kim JS; Soucek J; Matousek J; Raines RT
    J Biol Chem; 1995 Dec; 270(52):31097-102. PubMed ID: 8537370
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A ribonuclease inhibitor resistant dimer of human pancreatic ribonuclease displays specific antitumor activity.
    Attery A; Dey P; Tripathi P; Batra JK
    Int J Biol Macromol; 2018 Feb; 107(Pt B):1965-1970. PubMed ID: 29042278
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Construction of Highly Stable Cytotoxic Nuclear-Directed Ribonucleases.
    Roura Padrosa D; Castro J; Romero-Casañas A; Ribó M; Vilanova M; Benito A
    Molecules; 2018 Dec; 23(12):. PubMed ID: 30544927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tandemization endows bovine pancreatic ribonuclease with cytotoxic activity.
    Leich F; Köditz J; Ulbrich-Hofman R; Arnold U
    J Mol Biol; 2006 May; 358(5):1305-13. PubMed ID: 16580680
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases.
    Thomas SP; Kim E; Kim JS; Raines RT
    Biochemistry; 2016 Nov; 55(46):6359-6362. PubMed ID: 27806571
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.
    Mashiko T; Sakashita E; Kasashima K; Tominaga K; Kuroiwa K; Nozaki Y; Matsuura T; Hamamoto T; Endo H
    J Biol Chem; 2016 Jul; 291(29):14996-5007. PubMed ID: 27226551
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Compensating effects on the cytotoxicity of ribonuclease A variants.
    Dickson KA; Dahlberg CL; Raines RT
    Arch Biochem Biophys; 2003 Jul; 415(2):172-7. PubMed ID: 12831839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor.
    Thomas SP; Hoang TT; Ressler VT; Raines RT
    RNA; 2018 Aug; 24(8):1018-1027. PubMed ID: 29748193
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation.
    Jeong SA; Kim K; Lee JH; Cha JS; Khadka P; Cho HS; Chung IK
    J Cell Sci; 2015 Jun; 128(12):2287-301. PubMed ID: 25999477
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A ribonuclease A variant with low catalytic activity but high cytotoxicity.
    Bretscher LE; Abel RL; Raines RT
    J Biol Chem; 2000 Apr; 275(14):9893-6. PubMed ID: 10744660
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of tumour growth on hepatic neutral ribonuclease and its inhibitor and on RNA polymerase activity of liver nuclei.
    Clark CM; Goodlad GA
    Enzyme; 1983; 30(4):239-43. PubMed ID: 6653544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of aspartic acid 121 in human pancreatic ribonuclease catalysis.
    Gaur D; Batra JK
    Mol Cell Biochem; 2005 Jul; 275(1-2):95-101. PubMed ID: 16335788
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.