165 related articles for article (PubMed ID: 20354984)
1. New approaches to the total synthesis of the bryostatin antitumor macrolides.
Hale KJ; Manaviazar S
Chem Asian J; 2010 Apr; 5(4):704-54. PubMed ID: 20354984
[TBL] [Abstract][Full Text] [Related]
2. Unlocking the Drug Potential of the Bryostatin Family: Recent Advances in Product Synthesis and Biomedical Applications.
Wu R; Chen H; Chang N; Xu Y; Jiao J; Zhang H
Chemistry; 2020 Jan; 26(6):1166-1195. PubMed ID: 31479550
[TBL] [Abstract][Full Text] [Related]
3. Total syntheses of bryostatins: synthesis of two ring-expanded bryostatin analogues and the development of a new-generation strategy to access the C7-C27 fragment.
Trost BM; Yang H; Dong G
Chemistry; 2011 Aug; 17(35):9789-805. PubMed ID: 21780195
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core.
Kraft MB; Poudel YB; Kedei N; Lewin NE; Peach ML; Blumberg PM; Keck GE
J Am Chem Soc; 2014 Sep; 136(38):13202-8. PubMed ID: 25207434
[TBL] [Abstract][Full Text] [Related]
5. Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters.
Keck GE; Poudel YB; Welch DS; Kraft MB; Truong AP; Stephens JC; Kedei N; Lewin NE; Blumberg PM
Org Lett; 2009 Feb; 11(3):593-6. PubMed ID: 19113896
[TBL] [Abstract][Full Text] [Related]
6. Preclinical and Clinical Studies on Bryostatins, A Class of Marine-Derived Protein Kinase C Modulators: A Mini-Review.
Raghuvanshi R; Bharate SB
Curr Top Med Chem; 2020; 20(12):1124-1135. PubMed ID: 32209043
[TBL] [Abstract][Full Text] [Related]
7. Total synthesis of bryostatin 16 using atom-economical and chemoselective approaches.
Trost BM; Dong G
Nature; 2008 Nov; 456(7221):485-8. PubMed ID: 19037312
[TBL] [Abstract][Full Text] [Related]
8. The design, synthesis, and evaluation of C7 diversified bryostatin analogs reveals a hot spot for PKC affinity.
Wender PA; Verma VA
Org Lett; 2008 Aug; 10(15):3331-4. PubMed ID: 18588309
[TBL] [Abstract][Full Text] [Related]
9. Total synthesis of bryostatin 16 using a Pd-catalyzed diyne coupling as macrocyclization method and synthesis of C20-epi-bryostatin 7 as a potent anticancer agent.
Trost BM; Dong G
J Am Chem Soc; 2010 Nov; 132(46):16403-16. PubMed ID: 21043491
[TBL] [Abstract][Full Text] [Related]
10. Bryostatin-1: pharmacology and therapeutic potential as a CNS drug.
Sun MK; Alkon DL
CNS Drug Rev; 2006; 12(1):1-8. PubMed ID: 16834754
[TBL] [Abstract][Full Text] [Related]
11. Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity.
Keck GE; Poudel YB; Rudra A; Stephens JC; Kedei N; Lewin NE; Blumberg PM
Bioorg Med Chem Lett; 2012 Jun; 22(12):4084-8. PubMed ID: 22579485
[TBL] [Abstract][Full Text] [Related]
12. Total synthesis of bryostatin 3.
Trost BM; Wang Y; Buckl AK; Huang Z; Nguyen MH; Kuzmina O
Science; 2020 May; 368(6494):1007-1011. PubMed ID: 32467391
[TBL] [Abstract][Full Text] [Related]
13. Biological profile of the less lipophilic and synthetically more accessible bryostatin 7 closely resembles that of bryostatin 1.
Kedei N; Lewin NE; Géczy T; Selezneva J; Braun DC; Chen J; Herrmann MA; Heldman MR; Lim L; Mannan P; Garfield SH; Poudel YB; Cummins TJ; Rudra A; Blumberg PM; Keck GE
ACS Chem Biol; 2013 Apr; 8(4):767-77. PubMed ID: 23369356
[TBL] [Abstract][Full Text] [Related]
14. Total synthesis of bryostatin 9.
Wender PA; Schrier AJ
J Am Chem Soc; 2011 Jun; 133(24):9228-31. PubMed ID: 21618969
[TBL] [Abstract][Full Text] [Related]
15. Bryostatins selectively regulate protein kinase C-mediated effects on GH4 cell proliferation.
Mackanos EA; Pettit GR; Ramsdell JS
J Biol Chem; 1991 Jun; 266(17):11205-12. PubMed ID: 1904062
[TBL] [Abstract][Full Text] [Related]
16. The bryostatins inhibit growth of B16/F10 melanoma cells in vitro through a protein kinase C-independent mechanism: dissociation of activities using 26-epi-bryostatin 1.
Szallasi Z; Du L; Levine R; Lewin NE; Nguyen PN; Williams MD; Pettit GR; Blumberg PM
Cancer Res; 1996 May; 56(9):2105-11. PubMed ID: 8616857
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of seco-B-ring bryostatin analogue WN-1 via C-C bond-forming hydrogenation: critical contribution of the B-ring in determining bryostatin-like and phorbol 12-myristate 13-acetate-like properties.
Andrews IP; Ketcham JM; Blumberg PM; Kedei N; Lewin NE; Peach ML; Krische MJ
J Am Chem Soc; 2014 Sep; 136(38):13209-16. PubMed ID: 25207655
[TBL] [Abstract][Full Text] [Related]
18. Total synthesis and initial biological evaluation of new B-ring-modified bryostatin analogs.
Wender PA; Horan JC; Verma VA
Org Lett; 2006 Nov; 8(23):5299-302. PubMed ID: 17078702
[TBL] [Abstract][Full Text] [Related]
19. Towards 20,20-difluorinated bryostatin: synthesis and biological evaluation of C17,C27-fragments.
Mears PR; Hoekman S; Rye CE; Bailey FP; Byrne DP; Eyers PA; Thomas EJ
Org Biomol Chem; 2019 Feb; 17(6):1487-1505. PubMed ID: 30681118
[TBL] [Abstract][Full Text] [Related]
20. The rational design of potential chemotherapeutic agents: synthesis of bryostatin analogues.
Wender PA; Hinkle KW; Koehler MF; Lippa B
Med Res Rev; 1999 Sep; 19(5):388-407. PubMed ID: 10502742
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
