These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 20356846)

  • 21. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.
    Feltham RL; Moulin M; Vince JE; Mace PD; Wong WW; Anderton H; Day CL; Vaux DL; Silke J
    J Biol Chem; 2017 Aug; 292(34):14310. PubMed ID: 28842477
    [No Abstract]   [Full Text] [Related]  

  • 22. Pathological activation of canonical nuclear-factor κB by synergy of tumor necrosis factor α and TNF-like weak inducer of apoptosis in mouse acute colitis.
    Dohi T; Kawashima R; Kawamura YI; Otsubo T; Hagiwara T; Amatucci A; Michaelson J; Burkly LC
    Cytokine; 2014 Sep; 69(1):14-21. PubMed ID: 25022957
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.
    Zarnegar BJ; Wang Y; Mahoney DJ; Dempsey PW; Cheung HH; He J; Shiba T; Yang X; Yeh WC; Mak TW; Korneluk RG; Cheng G
    Nat Immunol; 2008 Dec; 9(12):1371-8. PubMed ID: 18997794
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.
    Vallabhapurapu S; Matsuzawa A; Zhang W; Tseng PH; Keats JJ; Wang H; Vignali DA; Bergsagel PL; Karin M
    Nat Immunol; 2008 Dec; 9(12):1364-70. PubMed ID: 18997792
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models.
    Benetatos CA; Mitsuuchi Y; Burns JM; Neiman EM; Condon SM; Yu G; Seipel ME; Kapoor GS; Laporte MG; Rippin SR; Deng Y; Hendi MS; Tirunahari PK; Lee YH; Haimowitz T; Alexander MD; Graham MA; Weng D; Shi Y; McKinlay MA; Chunduru SK
    Mol Cancer Ther; 2014 Apr; 13(4):867-79. PubMed ID: 24563541
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are increased after labour in foetal membranes and myometrium and are essential for TNF-α-induced expression of pro-labour mediators.
    Lappas M
    Am J Reprod Immunol; 2015 Apr; 73(4):313-29. PubMed ID: 25046208
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Proinflammatory cytokine tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) suppresses satellite cell self-renewal through inversely modulating Notch and NF-κB signaling pathways.
    Ogura Y; Mishra V; Hindi SM; Kuang S; Kumar A
    J Biol Chem; 2013 Dec; 288(49):35159-69. PubMed ID: 24151074
    [TBL] [Abstract][Full Text] [Related]  

  • 28. ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.
    Ward GA; Lewis EJ; Ahn JS; Johnson CN; Lyons JF; Martins V; Munck JM; Rich SJ; Smyth T; Thompson NT; Williams PA; Wilsher NE; Wallis NG; Chessari G
    Mol Cancer Ther; 2018 Jul; 17(7):1381-1391. PubMed ID: 29695633
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Tumor necrosis factor-α-induced apoptosis of gastric cancer MKN28 cells: accelerated degradation of the inhibitor of apoptosis family members.
    Kitagawa M; Shiozaki A; Ichikawa D; Nakashima S; Kosuga T; Konishi H; Komatsu S; Fujiwara H; Okamoto K; Otsuji E
    Arch Biochem Biophys; 2015 Jan; 566():43-8. PubMed ID: 25513960
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The Role of Ubiquitination in TWEAK-Stimulated Signaling.
    Vucic D
    Front Immunol; 2013 Dec; 4():472. PubMed ID: 24391645
    [TBL] [Abstract][Full Text] [Related]  

  • 31. TWEAK and cIAP1 regulate myoblast fusion through the noncanonical NF-κB signaling pathway.
    Enwere EK; Holbrook J; Lejmi-Mrad R; Vineham J; Timusk K; Sivaraj B; Isaac M; Uehling D; Al-awar R; LaCasse E; Korneluk RG
    Sci Signal; 2012 Oct; 5(246):ra75. PubMed ID: 23074266
    [TBL] [Abstract][Full Text] [Related]  

  • 32. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
    Vince JE; Wong WW; Khan N; Feltham R; Chau D; Ahmed AU; Benetatos CA; Chunduru SK; Condon SM; McKinlay M; Brink R; Leverkus M; Tergaonkar V; Schneider P; Callus BA; Koentgen F; Vaux DL; Silke J
    Cell; 2007 Nov; 131(4):682-93. PubMed ID: 18022363
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling.
    Wang YB; Tan B; Mu R; Chang Y; Wu M; Tu HQ; Zhang YC; Guo SS; Qin XH; Li T; Li WH; Li AL; Zhang XM; Li HY
    J Biol Chem; 2015 Apr; 290(16):10395-405. PubMed ID: 25681446
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Tumor Necrosis Factor (TNF) Receptor Expression Determines Keratinocyte Fate upon Stimulation with TNF-Like Weak Inducer of Apoptosis.
    Wang X; Cheng D; Hu G; Liang L; Tan F; Xiao T; Xiao S; Xia Y
    Mediators Inflamm; 2019; 2019():2945083. PubMed ID: 31885495
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes.
    Feoktistova M; Makarov R; Brenji S; Schneider AT; Hooiveld GJ; Luedde T; Leverkus M; Yazdi AS; Panayotova-Dimitrova D
    Cells; 2020 Feb; 9(2):. PubMed ID: 32028675
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis.
    Welsh K; Milutinovic S; Ardecky RJ; Gonzalez-Lopez M; Ganji SR; Teriete P; Finlay D; Riedl S; Matsuzawa S; Pinilla C; Houghten R; Vuori K; Reed JC; Cosford ND
    PLoS One; 2016; 11(9):e0161952. PubMed ID: 27617834
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways.
    Cheung HH; Plenchette S; Kern CJ; Mahoney DJ; Korneluk RG
    Mol Biol Cell; 2008 Jul; 19(7):2729-40. PubMed ID: 18434593
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein.
    Dogra C; Changotra H; Mohan S; Kumar A
    J Biol Chem; 2006 Apr; 281(15):10327-36. PubMed ID: 16461349
    [TBL] [Abstract][Full Text] [Related]  

  • 39. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.
    Varfolomeev E; Blankenship JW; Wayson SM; Fedorova AV; Kayagaki N; Garg P; Zobel K; Dynek JN; Elliott LO; Wallweber HJ; Flygare JA; Fairbrother WJ; Deshayes K; Dixit VM; Vucic D
    Cell; 2007 Nov; 131(4):669-81. PubMed ID: 18022362
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1).
    Blankenship JW; Varfolomeev E; Goncharov T; Fedorova AV; Kirkpatrick DS; Izrael-Tomasevic A; Phu L; Arnott D; Aghajan M; Zobel K; Bazan JF; Fairbrother WJ; Deshayes K; Vucic D
    Biochem J; 2009 Jan; 417(1):149-60. PubMed ID: 18939944
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.