BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 20358439)

  • 1. Multiple comparisons of repeated measured response: issues of assessment of prolongation of QT interval in thorough QT trials.
    Tsong Y; Zhong J
    J Biopharm Stat; 2010 May; 20(3):604-14. PubMed ID: 20358439
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multiple comparisons of repeatedly measured response: issues of validation testing in thorough QT/QTc clinical trials.
    Tsong Y; Yan LK; Zhong J; Nie L; Zhang J
    J Biopharm Stat; 2010 May; 20(3):654-64. PubMed ID: 20358443
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Statistical issues of QT prolongation assessment based on linear concentration modeling.
    Tsong Y; Shen M; Zhong J; Zhang J
    J Biopharm Stat; 2008; 18(3):564-84. PubMed ID: 18470764
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exposure-response modeling approach for assessing QT effect in "thorough" QT/QTc studies.
    Hosmane B; Locke C; Chiu YL
    J Biopharm Stat; 2010 May; 20(3):615-31. PubMed ID: 20358440
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sample size and power estimation in "thorough" QT/QTc studies with parallel group design.
    Hosmane B; Locke C; Chiu YL
    J Biopharm Stat; 2010 May; 20(3):578-86. PubMed ID: 20358437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sample size calculation for thorough QT/QTc study considering various factors related to multiple time points.
    Meng Z; Kringle R; Chen X; Zhao PL
    J Biopharm Stat; 2010 May; 20(3):563-77. PubMed ID: 20358436
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Statistical characterization of QT prolongation.
    Schall R; Ring A
    J Biopharm Stat; 2010 May; 20(3):543-62. PubMed ID: 20358435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sample size, power calculations, and their implications for the cost of thorough studies of drug induced QT interval prolongation.
    Malik M; Hnatkova K; Batchvarov V; Gang Y; Smetana P; Camm AJ
    Pacing Clin Electrophysiol; 2004 Dec; 27(12):1659-69. PubMed ID: 15613131
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Statistical consideration in testing for assay sensitivity in a "thorough" QT study.
    Sethuraman V; Wu S; Wang J
    J Biopharm Stat; 2010 May; 20(3):641-53. PubMed ID: 20358442
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Statistical characteristics of moxifloxacin-induced QTc effect.
    Yan LK; Zhang J; Ng MJ; Dang Q
    J Biopharm Stat; 2010 May; 20(3):497-507. PubMed ID: 20358432
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Use of the average baseline versus the time-matched baseline in parallel group thorough QT/QTc studies.
    Meng Z; Quan H; Fan L; Kringle R; Sun G
    J Biopharm Stat; 2010 May; 20(3):665-82. PubMed ID: 20358444
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Bayesian measurement error approach to QT interval correction and prolongation.
    Chen J; Zhao X
    J Biopharm Stat; 2010 May; 20(3):523-42. PubMed ID: 20358434
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mixed models for data from thorough QT studies: part 1. assessment of marginal QT prolongation.
    Schall R; Ring A
    Pharm Stat; 2011; 10(3):265-76. PubMed ID: 21574242
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sample size calculations for crossover thorough QT studies: satisfaction of regulatory threshold and assay sensitivity.
    Anand SP; Murray SC; Koch GG
    J Biopharm Stat; 2010 May; 20(3):587-603. PubMed ID: 20358438
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of levetiracetam on cardiac repolarization in healthy subjects: a single-dose, randomized, placebo- and active-controlled, four-way crossover study.
    Hulhoven R; Rosillon D; Bridson WE; Meeus MA; Salas E; Stockis A
    Clin Ther; 2008 Feb; 30(2):260-70. PubMed ID: 18343264
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Statistical issues including design and sample size calculation in thorough QT/QTc studies.
    Zhang J; Machado SG
    J Biopharm Stat; 2008; 18(3):451-67. PubMed ID: 18470755
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Testing for positive control activity in a thorough QTc study.
    Zhang J
    J Biopharm Stat; 2008; 18(3):517-28. PubMed ID: 18470760
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Validation testing in thorough QT/QTc clinical trials.
    Tsong Y; Zhong J; Chen WJ
    J Biopharm Stat; 2008; 18(3):529-41. PubMed ID: 18470761
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Further discussion on the design and analysis of thorough QTc clinical trials: guest editors' notes.
    Tsong Y; Zhang J
    J Biopharm Stat; 2010 May; 20(3):493-6. PubMed ID: 20358431
    [No Abstract]   [Full Text] [Related]  

  • 20. A comparison of several methods for analyzing data from thorough QT studies.
    Tian H; Qiao W; Natarajan J
    J Biopharm Stat; 2010 May; 20(3):632-40. PubMed ID: 20358441
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.