364 related articles for article (PubMed ID: 20367107)
1. Hepatotoxicity and hepatic metabolism of available drugs: current problems and possible solutions in preclinical stages.
Giri S; Nieber K; Bader A
Expert Opin Drug Metab Toxicol; 2010 Aug; 6(8):895-917. PubMed ID: 20367107
[TBL] [Abstract][Full Text] [Related]
2. In vitro evaluation of potential hepatotoxicity induced by drugs.
Gómez-Lechón MJ; Lahoz A; Gombau L; Castell JV; Donato MT
Curr Pharm Des; 2010 Jun; 16(17):1963-77. PubMed ID: 20236064
[TBL] [Abstract][Full Text] [Related]
3. Role of reactive metabolites in drug-induced hepatotoxicity.
Srivastava A; Maggs JL; Antoine DJ; Williams DP; Smith DA; Park BK
Handb Exp Pharmacol; 2010; (196):165-94. PubMed ID: 20020263
[TBL] [Abstract][Full Text] [Related]
4. The role of metabolic activation in drug-induced hepatotoxicity.
Park BK; Kitteringham NR; Maggs JL; Pirmohamed M; Williams DP
Annu Rev Pharmacol Toxicol; 2005; 45():177-202. PubMed ID: 15822174
[TBL] [Abstract][Full Text] [Related]
5. [Reactive metabolites of xenobiotics : their role in the hepatotoxicity of drugs].
Pessayre D; Benhamou JP
C R Seances Soc Biol Fil; 1979; 173(2):458-68. PubMed ID: 159767
[TBL] [Abstract][Full Text] [Related]
6. Drug-induced hepatotoxicity.
Lee WM
N Engl J Med; 1995 Oct; 333(17):1118-27. PubMed ID: 7565951
[No Abstract] [Full Text] [Related]
7. [Hepatic tolerance of atypical antipsychotic drugs].
Dumortier G; Cabaret W; Stamatiadis L; Saba G; Benadhira R; Rocamora JF; Aubriot-Delmas B; Glikman J; Januel D
Encephale; 2002; 28(6 Pt 1):542-51. PubMed ID: 12506267
[TBL] [Abstract][Full Text] [Related]
8. Role of metabolism in drug-induced idiosyncratic hepatotoxicity.
Walgren JL; Mitchell MD; Thompson DC
Crit Rev Toxicol; 2005; 35(4):325-61. PubMed ID: 15989140
[TBL] [Abstract][Full Text] [Related]
9. Drug reactive metabolite-induced hepatotoxicity: a comprehensive review.
Mahajan P; Palkar M; Pingili RB
Toxicol Mech Methods; 2024 Jul; 34(6):607-627. PubMed ID: 38504503
[TBL] [Abstract][Full Text] [Related]
10. Toxicophores: investigations in drug safety.
Williams DP
Toxicology; 2006 Sep; 226(1):1-11. PubMed ID: 16860917
[TBL] [Abstract][Full Text] [Related]
11. Review article: drug-induced hepatotoxicity.
Lee WM
Aliment Pharmacol Ther; 1993 Oct; 7(5):477-85. PubMed ID: 8280816
[TBL] [Abstract][Full Text] [Related]
12. Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Sakatis MZ; Reese MJ; Harrell AW; Taylor MA; Baines IA; Chen L; Bloomer JC; Yang EY; Ellens HM; Ambroso JL; Lovatt CA; Ayrton AD; Clarke SE
Chem Res Toxicol; 2012 Oct; 25(10):2067-82. PubMed ID: 22931300
[TBL] [Abstract][Full Text] [Related]
13. Drug metabolite profiling and elucidation of drug-induced hepatotoxicity.
Tang W
Expert Opin Drug Metab Toxicol; 2007 Jun; 3(3):407-20. PubMed ID: 17539747
[TBL] [Abstract][Full Text] [Related]
14. Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development.
Blomme EA; Yang Y; Waring JF
Toxicol Lett; 2009 Apr; 186(1):22-31. PubMed ID: 18996174
[TBL] [Abstract][Full Text] [Related]
15. Detection of nanolevel drug metabolites in an organotypic culture of primary human hepatocytes and porcine hepatocytes with special reference to a two-compartment model.
Acikgöz A; Giri S; Bader A
Int J Nanomedicine; 2012; 7():5859-72. PubMed ID: 23226017
[TBL] [Abstract][Full Text] [Related]
16. Hepatotoxicity by Drugs: The Most Common Implicated Agents.
Björnsson ES
Int J Mol Sci; 2016 Feb; 17(2):224. PubMed ID: 26861310
[TBL] [Abstract][Full Text] [Related]
17. Idiosyncratic drug hepatotoxicity.
Kaplowitz N
Nat Rev Drug Discov; 2005 Jun; 4(6):489-99. PubMed ID: 15931258
[TBL] [Abstract][Full Text] [Related]
18. [Hepatic cytoprotection (3). Mechanisms of protection against the hepatotoxicity of drugs].
Larrey D
Gastroenterol Clin Biol; 1989 Jun; 13(6-7):572-6. PubMed ID: 2666245
[No Abstract] [Full Text] [Related]
19. [Drug damage to the liver: role of reactive metabolites and pharmacokinetics].
Lauterburg BH
Schweiz Med Wochenschr; 1985 Sep; 115(38):1306-12. PubMed ID: 3933110
[TBL] [Abstract][Full Text] [Related]
20. Selection of new chemical entities with decreased potential for adverse drug reactions.
Park KB; Dalton-Brown E; Hirst C; Williams DP
Eur J Pharmacol; 2006 Nov; 549(1-3):1-8. PubMed ID: 16979156
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
