365 related articles for article (PubMed ID: 20367107)
21. Metabolic bioactivation and drug-related adverse effects: current status and future directions from a pharmaceutical research perspective.
Tang W; Lu AY
Drug Metab Rev; 2010 May; 42(2):225-49. PubMed ID: 19939207
[TBL] [Abstract][Full Text] [Related]
22. Drugs and the liver.
Papich MG; Davis LE
Vet Clin North Am Small Anim Pract; 1985 Jan; 15(1):77-95. PubMed ID: 3872507
[TBL] [Abstract][Full Text] [Related]
23. Metabolic activation in drug-induced liver injury.
Leung L; Kalgutkar AS; Obach RS
Drug Metab Rev; 2012 Feb; 44(1):18-33. PubMed ID: 21939431
[TBL] [Abstract][Full Text] [Related]
24. Drugs and the liver: advances in metabolism, toxicity, and therapeutics.
Buratti S; Lavine JE
Curr Opin Pediatr; 2002 Oct; 14(5):601-7. PubMed ID: 12352255
[TBL] [Abstract][Full Text] [Related]
25. Drug-induced liver injury.
Holt M; Ju C
Handb Exp Pharmacol; 2010; (196):3-27. PubMed ID: 20020257
[TBL] [Abstract][Full Text] [Related]
26. Understanding the role of reactive metabolites in drug-induced hepatotoxicity: state of the science.
Antoine DJ; Williams DP; Park BK
Expert Opin Drug Metab Toxicol; 2008 Nov; 4(11):1415-27. PubMed ID: 18950283
[TBL] [Abstract][Full Text] [Related]
27. High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury.
Chen M; Borlak J; Tong W
Hepatology; 2013 Jul; 58(1):388-96. PubMed ID: 23258593
[TBL] [Abstract][Full Text] [Related]
28. Reactive Metabolites: Current and Emerging Risk and Hazard Assessments.
Thompson RA; Isin EM; Ogese MO; Mettetal JT; Williams DP
Chem Res Toxicol; 2016 Apr; 29(4):505-33. PubMed ID: 26735163
[TBL] [Abstract][Full Text] [Related]
29. An algorithm for monitoring and managing drug hepatotoxicity.
Hofmann AF; Thistle JL
Gastroenterology; 1974 Aug; 67(2):309-13. PubMed ID: 4847711
[No Abstract] [Full Text] [Related]
30. The use of hepatocytes to investigate drug toxicity.
Gómez-Lechón MJ; Castell JV; Donato MT
Methods Mol Biol; 2010; 640():389-415. PubMed ID: 20645064
[TBL] [Abstract][Full Text] [Related]
31. [Hepatic toxicity of drugs].
Adler M
Rev Med Brux; 1994; 15(4):217-22. PubMed ID: 7938992
[TBL] [Abstract][Full Text] [Related]
32. Important role of proinflammatory cytokines/other endogenous substances in drug-induced hepatotoxicity: depression of drug metabolism during infections/inflammation states, and genetic polymorphisms of drug-metabolizing enzymes/cytokines may markedly contribute to this pathology.
Prandota J
Am J Ther; 2005; 12(3):254-61. PubMed ID: 15891270
[TBL] [Abstract][Full Text] [Related]
33. Are chemically reactive metabolites responsible for adverse reactions to drugs?
Williams DP; Kitteringham NR; Naisbitt DJ; Pirmohamed M; Smith DA; Park BK
Curr Drug Metab; 2002 Aug; 3(4):351-66. PubMed ID: 12093355
[TBL] [Abstract][Full Text] [Related]
34. [Drug- and toxin-induced hepatotoxicity].
Grünhage F; Fischer HP; Sauerbruch T; Reichel C
Z Gastroenterol; 2003 Jun; 41(6):565-78. PubMed ID: 12806543
[TBL] [Abstract][Full Text] [Related]
35. Drugs of abuse and addiction: A slippery slope toward liver injury.
Roy DN; Goswami R
Chem Biol Interact; 2016 Aug; 255():92-105. PubMed ID: 26409324
[TBL] [Abstract][Full Text] [Related]
36. Challenges and solutions to metabolites in safety testing: impact of the International Conference on Harmonization M3(R2) guidance.
Yu H; Bischoff D; Tweedie D
Expert Opin Drug Metab Toxicol; 2010 Dec; 6(12):1539-49. PubMed ID: 21067462
[TBL] [Abstract][Full Text] [Related]
37. The generation, detection, and effects of reactive drug metabolites.
Stachulski AV; Baillie TA; Park BK; Obach RS; Dalvie DK; Williams DP; Srivastava A; Regan SL; Antoine DJ; Goldring CE; Chia AJ; Kitteringham NR; Randle LE; Callan H; Castrejon JL; Farrell J; Naisbitt DJ; Lennard MS
Med Res Rev; 2013 Sep; 33(5):985-1080. PubMed ID: 23090860
[TBL] [Abstract][Full Text] [Related]
38. Drug-induced hepatotoxicity.
Lee WM
N Engl J Med; 2003 Jul; 349(5):474-85. PubMed ID: 12890847
[No Abstract] [Full Text] [Related]
39. [Liver lesions caused by drugs and environmental pollutants. Free radicals and reactive metabolites. I].
Mariani L; Baratelli M
Clin Ter; 1982 Nov; 103(3):237-65. PubMed ID: 7151380
[No Abstract] [Full Text] [Related]
40. Liver.
Piñeiro-Carrero VM; Piñeiro EO
Pediatrics; 2004 Apr; 113(4 Suppl):1097-106. PubMed ID: 15060205
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]