BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

365 related articles for article (PubMed ID: 20367107)

  • 21. Metabolic bioactivation and drug-related adverse effects: current status and future directions from a pharmaceutical research perspective.
    Tang W; Lu AY
    Drug Metab Rev; 2010 May; 42(2):225-49. PubMed ID: 19939207
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Drugs and the liver.
    Papich MG; Davis LE
    Vet Clin North Am Small Anim Pract; 1985 Jan; 15(1):77-95. PubMed ID: 3872507
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Metabolic activation in drug-induced liver injury.
    Leung L; Kalgutkar AS; Obach RS
    Drug Metab Rev; 2012 Feb; 44(1):18-33. PubMed ID: 21939431
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Drugs and the liver: advances in metabolism, toxicity, and therapeutics.
    Buratti S; Lavine JE
    Curr Opin Pediatr; 2002 Oct; 14(5):601-7. PubMed ID: 12352255
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Drug-induced liver injury.
    Holt M; Ju C
    Handb Exp Pharmacol; 2010; (196):3-27. PubMed ID: 20020257
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Understanding the role of reactive metabolites in drug-induced hepatotoxicity: state of the science.
    Antoine DJ; Williams DP; Park BK
    Expert Opin Drug Metab Toxicol; 2008 Nov; 4(11):1415-27. PubMed ID: 18950283
    [TBL] [Abstract][Full Text] [Related]  

  • 27. High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury.
    Chen M; Borlak J; Tong W
    Hepatology; 2013 Jul; 58(1):388-96. PubMed ID: 23258593
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Reactive Metabolites: Current and Emerging Risk and Hazard Assessments.
    Thompson RA; Isin EM; Ogese MO; Mettetal JT; Williams DP
    Chem Res Toxicol; 2016 Apr; 29(4):505-33. PubMed ID: 26735163
    [TBL] [Abstract][Full Text] [Related]  

  • 29. An algorithm for monitoring and managing drug hepatotoxicity.
    Hofmann AF; Thistle JL
    Gastroenterology; 1974 Aug; 67(2):309-13. PubMed ID: 4847711
    [No Abstract]   [Full Text] [Related]  

  • 30. The use of hepatocytes to investigate drug toxicity.
    Gómez-Lechón MJ; Castell JV; Donato MT
    Methods Mol Biol; 2010; 640():389-415. PubMed ID: 20645064
    [TBL] [Abstract][Full Text] [Related]  

  • 31. [Hepatic toxicity of drugs].
    Adler M
    Rev Med Brux; 1994; 15(4):217-22. PubMed ID: 7938992
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Important role of proinflammatory cytokines/other endogenous substances in drug-induced hepatotoxicity: depression of drug metabolism during infections/inflammation states, and genetic polymorphisms of drug-metabolizing enzymes/cytokines may markedly contribute to this pathology.
    Prandota J
    Am J Ther; 2005; 12(3):254-61. PubMed ID: 15891270
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Are chemically reactive metabolites responsible for adverse reactions to drugs?
    Williams DP; Kitteringham NR; Naisbitt DJ; Pirmohamed M; Smith DA; Park BK
    Curr Drug Metab; 2002 Aug; 3(4):351-66. PubMed ID: 12093355
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [Drug- and toxin-induced hepatotoxicity].
    Grünhage F; Fischer HP; Sauerbruch T; Reichel C
    Z Gastroenterol; 2003 Jun; 41(6):565-78. PubMed ID: 12806543
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Drugs of abuse and addiction: A slippery slope toward liver injury.
    Roy DN; Goswami R
    Chem Biol Interact; 2016 Aug; 255():92-105. PubMed ID: 26409324
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Challenges and solutions to metabolites in safety testing: impact of the International Conference on Harmonization M3(R2) guidance.
    Yu H; Bischoff D; Tweedie D
    Expert Opin Drug Metab Toxicol; 2010 Dec; 6(12):1539-49. PubMed ID: 21067462
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The generation, detection, and effects of reactive drug metabolites.
    Stachulski AV; Baillie TA; Park BK; Obach RS; Dalvie DK; Williams DP; Srivastava A; Regan SL; Antoine DJ; Goldring CE; Chia AJ; Kitteringham NR; Randle LE; Callan H; Castrejon JL; Farrell J; Naisbitt DJ; Lennard MS
    Med Res Rev; 2013 Sep; 33(5):985-1080. PubMed ID: 23090860
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Drug-induced hepatotoxicity.
    Lee WM
    N Engl J Med; 2003 Jul; 349(5):474-85. PubMed ID: 12890847
    [No Abstract]   [Full Text] [Related]  

  • 39. [Liver lesions caused by drugs and environmental pollutants. Free radicals and reactive metabolites. I].
    Mariani L; Baratelli M
    Clin Ter; 1982 Nov; 103(3):237-65. PubMed ID: 7151380
    [No Abstract]   [Full Text] [Related]  

  • 40. Liver.
    Piñeiro-Carrero VM; Piñeiro EO
    Pediatrics; 2004 Apr; 113(4 Suppl):1097-106. PubMed ID: 15060205
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.