BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 20371333)

  • 1. Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease.
    Cheng SC; Chang GG; Chou CY
    Biophys J; 2010 Apr; 98(7):1327-36. PubMed ID: 20371333
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease.
    Wu CG; Cheng SC; Chen SC; Li JY; Fang YH; Chen YH; Chou CY
    Acta Crystallogr D Biol Crystallogr; 2013 May; 69(Pt 5):747-55. PubMed ID: 23633583
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism for controlling the dimer-monomer switch and coupling dimerization to catalysis of the severe acute respiratory syndrome coronavirus 3C-like protease.
    Shi J; Sivaraman J; Song J
    J Virol; 2008 May; 82(9):4620-9. PubMed ID: 18305031
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.
    Tomar S; Johnston ML; St John SE; Osswald HL; Nyalapatla PR; Paul LN; Ghosh AK; Denison MR; Mesecar AD
    J Biol Chem; 2015 Aug; 290(32):19403-22. PubMed ID: 26055715
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations.
    Chen S; Hu T; Zhang J; Chen J; Chen K; Ding J; Jiang H; Shen X
    J Biol Chem; 2008 Jan; 283(1):554-564. PubMed ID: 17977841
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Only one protomer is active in the dimer of SARS 3C-like proteinase.
    Chen H; Wei P; Huang C; Tan L; Liu Y; Lai L
    J Biol Chem; 2006 May; 281(20):13894-8. PubMed ID: 16565086
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Critical Assessment of the Important Residues Involved in the Dimerization and Catalysis of MERS Coronavirus Main Protease.
    Ho BL; Cheng SC; Shi L; Wang TY; Ho KI; Chou CY
    PLoS One; 2015; 10(12):e0144865. PubMed ID: 26658006
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Residues on the dimer interface of SARS coronavirus 3C-like protease: dimer stability characterization and enzyme catalytic activity analysis.
    Chen S; Zhang J; Hu T; Chen K; Jiang H; Shen X
    J Biochem; 2008 Apr; 143(4):525-36. PubMed ID: 18182387
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dissection study on the severe acute respiratory syndrome 3C-like protease reveals the critical role of the extra domain in dimerization of the enzyme: defining the extra domain as a new target for design of highly specific protease inhibitors.
    Shi J; Wei Z; Song J
    J Biol Chem; 2004 Jun; 279(23):24765-73. PubMed ID: 15037623
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain.
    Shi J; Han N; Lim L; Lua S; Sivaraman J; Wang L; Mu Y; Song J
    PLoS Comput Biol; 2011 Feb; 7(2):e1001084. PubMed ID: 21390281
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutation of Asn28 disrupts the dimerization and enzymatic activity of SARS 3CL(pro) .
    Barrila J; Gabelli SB; Bacha U; Amzel LM; Freire E
    Biochemistry; 2010 May; 49(20):4308-17. PubMed ID: 20420403
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site.
    Lee J; Worrall LJ; Vuckovic M; Rosell FI; Gentile F; Ton AT; Caveney NA; Ban F; Cherkasov A; Paetzel M; Strynadka NCJ
    Nat Commun; 2020 Nov; 11(1):5877. PubMed ID: 33208735
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of the SARS coronavirus main proteinase as an active C2 crystallographic dimer.
    Xu T; Ooi A; Lee HC; Wilmouth R; Liu DX; Lescar J
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Nov; 61(Pt 11):964-6. PubMed ID: 16511208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Critical assessment of important regions in the subunit association and catalytic action of the severe acute respiratory syndrome coronavirus main protease.
    Hsu WC; Chang HC; Chou CY; Tsai PJ; Lin PI; Chang GG
    J Biol Chem; 2005 Jun; 280(24):22741-8. PubMed ID: 15831489
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insight into the activity of SARS main protease: Molecular dynamics study of dimeric and monomeric form of enzyme.
    Zheng K; Ma G; Zhou J; Zen M; Zhao W; Jiang Y; Yu Q; Feng J
    Proteins; 2007 Feb; 66(2):467-79. PubMed ID: 17083088
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure.
    Hu T; Zhang Y; Li L; Wang K; Chen S; Chen J; Ding J; Jiang H; Shen X
    Virology; 2009 Jun; 388(2):324-34. PubMed ID: 19409595
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease.
    Kovalevsky A; Aniana A; Coates L; Ghirlando R; Nashed NT; Louis JM
    J Mol Biol; 2024 Jul; 436(13):168616. PubMed ID: 38762033
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode.
    Chen S; Jonas F; Shen C; Hilgenfeld R
    Protein Cell; 2010 Jan; 1(1):59-74. PubMed ID: 21203998
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dynamically-driven enhancement of the catalytic machinery of the SARS 3C-like protease by the S284-T285-I286/A mutations on the extra domain.
    Lim L; Shi J; Mu Y; Song J
    PLoS One; 2014; 9(7):e101941. PubMed ID: 25036652
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Correlation between dissociation and catalysis of SARS-CoV main protease.
    Lin PY; Chou CY; Chang HC; Hsu WC; Chang GG
    Arch Biochem Biophys; 2008 Apr; 472(1):34-42. PubMed ID: 18275836
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.